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    • Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
    UCSF
    ZINC Item Suppliers, Protomers, & Similar Substances

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

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    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 5880 0.27 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.42 5.93 -31.88 2 8 0 87 366.377 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

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    Vendors

    And 13 More

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 490 0.35 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.21 7.8 -26.78 2 6 0 68 356.813 3 ↓
    Lo Low (pH 4.5-6) 2.84 6.43 -39.07 3 6 1 73 357.821 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-3-[4-(trifluoromethyl)phenyl]urea 1-(1,5-dimethyl-3-oxo-2-phenyl-p…

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    Vendors

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 100 0.35 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.43 8.15 -30.98 2 6 0 68 390.365 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1-(3-fluoro-4-methyl-phenyl)urea 3-(1,5-dimethyl-3-oxo-2-phenyl-p…

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    Vendors

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 980 0.32 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.07 7.74 -34.45 2 6 0 68 354.385 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(4-cyanophenyl)-3-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)urea 1-(4-cyanophenyl)-3-(3-keto-1,5-…

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    Vendors

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 3700 0.29 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.29 7.68 -28.81 2 7 0 92 347.378 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-3-[4-(methylthio)phenyl]urea 1-(3-keto-1,5-dimethyl-2-phenyl-…

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    And 1 More

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 170 0.36 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.96 -1.25 -28.98 2 6 0 68 368.462 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid 2-phenyl-2,3-dihydro-1H-imidazo[…

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    Vendors

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR1-2-E Formyl Peptide Receptor 1 (cluster #2 Of 2), Eukaryotic Eukaryotes 1 0.74 Functional ≤ 10μM
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 1 0.74 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.31 4.78 -54.68 1 5 -1 70 228.231 2 ↓
    Mid Mid (pH 6-8) 1.31 4.94 -47.41 2 5 0 71 229.239 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid 2-phenyl-2,3-dihydro-1H-imidazo[…

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    Vendors

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR1-2-E Formyl Peptide Receptor 1 (cluster #2 Of 2), Eukaryotic Eukaryotes 1 0.74 Functional ≤ 10μM
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 1 0.74 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.31 4.76 -54.64 1 5 -1 70 228.231 2 ↓
    Mid Mid (pH 6-8) 1.31 4.91 -47.37 2 5 0 71 229.239 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(2-Ethyl-benzoimidazol-1-yl)-piperidin-1-yl]-(5-methoxy-1H-indol-2-yl)-methanone [4-(2-Ethyl-benzoimidazol-1-yl)-…

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    Vendors

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 690 0.29 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 4.10 10.62 -17.93 1 6 0 63 402.498 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-3-(4-methoxyphenyl)-urea 1-(1,5-dimethyl-3-oxo-2-phenyl-p…

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    Vendors

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 2730 0.30 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.59 6.57 -28.35 2 7 0 77 352.394 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(4-bromophenyl)-3-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)urea 1-(4-bromophenyl)-3-(3-keto-1,5-…

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    Vendors

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 90 0.39 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.34 -1.65 -27.21 2 6 0 68 401.264 3 ↓

    Analogs

    8272528
    8272528

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(4-ethylphenyl)-3-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)urea 1-(4-ethylphenyl)-3-(3-keto-1,5-…

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    And 1 More

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 770 0.33 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.45 9.1 -28.66 2 6 0 68 350.422 4 ↓
    Mid Mid (pH 6-8) 3.07 5.1 -57.87 1 6 -1 74 349.414 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N'-(4-fluorophenyl)urea N-(1,5-dimethyl-2-phenyl-2,3-dih…

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    And 11 More

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    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 4850 0.30 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.69 7.35 -27.27 2 6 0 68 340.358 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: (5-Methoxy-1H-indol-2-yl)-[4-(2-methyl-benzoimidazol-1-yl)-piperidin-1-yl]-methanone (5-Methoxy-1H-indol-2-yl)-[4-(2-…

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    Vendors

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 1020 0.29 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.53 10.03 -18.46 1 6 0 63 388.471 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

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    And 7 More

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    FPR2-2-E Lipoxin A4 Receptor (cluster #2 Of 2), Eukaryotic Eukaryotes 1260 0.33 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.98 8.33 -28.9 2 6 0 68 336.395 3 ↓

    Parameters Provided:

    annotation.name = FPR2_HUMAN
anotation.type = F10
page.format = summary
page.num = 1
filter.purchasability = purchasable

    Structural Results Found: (before additional filtering)

    SQL Query Was

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    Permalink

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    Embed Link to Results

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