UCSF

Mitogen-activated Protein Kinase Kinase Kinase 1, Human (1 Compounds)

Swissprot:
M3K1_HUMAN
Stitch:
M3K1_HUMAN
UniProt:
Q13233
ChEMBL:
CHEMBL3956
Reactome:
REACT_163701
REACT_27215
REACT_6788
REACT_25024
REACT_24969
PDB:
MAP3K1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 0
Binding ≤ 1μM 0 0 0 0
Functional ≤ 10μM 1 0 0 0

Reactome Network (5)

Reactome ID Description Species
REACT_163701 FCERI mediated MAPK activation Homo sapiens
REACT_27215 MyD88 cascade initiated on plasma membrane Homo sapiens
REACT_6788 MyD88:Mal cascade initiated on plasma membrane Homo sapiens
REACT_25024 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Homo sapiens
REACT_24969 TRAF6 mediated NF-kB activation Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 19 5 4 4
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 43 9 5 6
M3K13_HUMAN O43283 CHEMBL1163124 Mitogen-activated Protein Kinase Kinase Kinase 13, Human 1 1 1 1
M3K14_HUMAN Q99558 CHEMBL5888 Mitogen-activated Protein Kinase Kinase Kinase 14, Human 2 1 1 1
M3K15_HUMAN Q6ZN16 CHEMBL1163127 Mitogen-activated Protein Kinase Kinase Kinase 15, Human 1 1 1 1
M3K2_HUMAN Q9Y2U5 CHEMBL5914 Mitogen-activated Protein Kinase Kinase Kinase 2, Human 1 1 1 1
M3K3_HUMAN Q99759 CHEMBL5970 Mitogen-activated Protein Kinase Kinase Kinase 3, Human 1 1 1 1
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 8 8 6 7
M3K5_HUMAN Q99683 CHEMBL5285 Mitogen-activated Protein Kinase Kinase Kinase 5, Human 9 5 4 1
M3K6_HUMAN O95382 CHEMBL1163123 Mitogen-activated Protein Kinase Kinase Kinase 6, Human 0 0 0 0
M3K7_HUMAN O43318 CHEMBL5776 Mitogen-activated Protein Kinase Kinase Kinase 7, Human 20 5 4 4
M3K8_HUMAN P41279 CHEMBL4899 Mitogen-activated Protein Kinase Kinase Kinase 8, Human 172 3 0 0
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 47 12 6 8

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 1
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 1