UCSF

Purine Nucleoside Phosphorylase, Human (262 Compounds)

Swissprot:
PNPH_HUMAN
Stitch:
PNPH_HUMAN
UniProt:
P00491
ChEMBL:
CHEMBL4338
Reactome:
REACT_2086
REACT_1923
PDB:
1M73 (DOCK)
1PF7 (DOCK)
1PWY (DOCK)
1RCT (DOCK)
1RFG (DOCK)
1RR6 (DOCK)
1RSZ (DOCK)
1RT9 (DOCK)
1ULA (DOCK)
1ULB (DOCK)
1V2H (DOCK)
1V3Q (DOCK)
1V41 (DOCK)
1V45 (DOCK)
1YRY (DOCK)
2A0W (DOCK)
2A0X (DOCK)
2A0Y (DOCK)
2OC4 (DOCK)
2OC9 (DOCK)
2ON6 (DOCK)
2Q7O (DOCK)
3BGS (DOCK)
3D1V (DOCK)
3GB9 (DOCK)
3GGS (DOCK)
3INY (DOCK)
3K8O (DOCK)
3K8Q (DOCK)
3PHB (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 262 5 2 3
Binding ≤ 1μM 230 3 1 2
Functional ≤ 10μM 8 2 0 1

Reactome Network (2)

Reactome ID Description Species
REACT_2086 Purine catabolism Homo sapiens
REACT_1923 Purine salvage Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PNPH_BOVIN P55859 CHEMBL2935 Purine Nucleoside Phosphorylase, Bovin 101 2 1 2
PNPH_MOUSE P23492 CHEMBL2215 Purine Nucleoside Phosphorylase, Mouse 5 0 0 0
PNPH_RAT P85973 CHEMBL2395 Purine-nucleoside Phosphorylase, Rat 28 3 2 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
PNPH_BOVIN P55859 CHEMBL2935 Purine Nucleoside Phosphorylase, Bovin 41
Q8T9Z7_PLAFA Q8T9Z7 CHEMBL5648 Purine Nucleoside Phosphorylase, Plafa 11
PNPH_RAT P85973 CHEMBL2395 Purine-nucleoside Phosphorylase, Rat 10
PNPH_MOUSE P23492 CHEMBL2215 Purine Nucleoside Phosphorylase, Mouse 3
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 3