| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Functional ≤ 10μM | 107 | 2 | 1 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_25222 | MyD88 dependent cascade initiated on endosome | Homo sapiens |
| REACT_9020 | Toll Like Receptor 7/8 (TLR7/8) Cascade | Homo sapiens |
| REACT_25024 | TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | Homo sapiens |
| REACT_25120 | TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | Homo sapiens |
| REACT_118632 | Trafficking and processing of endosomal TLR | Homo sapiens |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| TLR2_HUMAN | O60603 | CHEMBL4163 | Toll-like Receptor 2, Human | 2 | 0 | 0 | 0 |
| TLR4_HUMAN | O00206 | CHEMBL5255 | Toll-like Receptor 4, Human | 8 | 1 | 0 | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| Z100081 | Z100081 | CHEMBL613107 | PBMC (Peripheral Blood Mononuclear Cells) | 3 |
| Z50643 | Z50643 | CHEMBL379 | Hepatitis C Virus | 2 |
