ZINC 12

Analogs

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Vendors

• Molport

  • MolPort-020-313-396

• Active BioPharma

  • 156
  • 113
  • 21

• AK Scientific

  • X7403

And 21 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ACV1B-1-E	Activin Receptor Type-1B (cluster #1 Of 1), Eukaryotic	Eukaryotes	3000	0.29	Binding ≤ 10μM
ADCK4-1-E	Uncharacterized AarF Domain-containing Protein Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3100	0.29	Binding ≤ 10μM
BRAF-1-E	Serine/threonine-protein Kinase B-raf (cluster #1 Of 1), Eukaryotic	Eukaryotes	710	0.32	Binding ≤ 10μM
CTRO-1-E	Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	420	0.33	Binding ≤ 10μM
DDR1-1-E	Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1000	0.31	Binding ≤ 10μM
DDR2-1-E	Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5000	0.27	Binding ≤ 10μM
EGFR-1-E	Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic	Eukaryotes	710	0.32	Binding ≤ 10μM
EPHA6-1-E	Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1200	0.31	Binding ≤ 10μM
EPHB2-1-E	Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7800	0.26	Binding ≤ 10μM
FRK-1-E	Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	4400	0.28	Binding ≤ 10μM
GAK-1-E	Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic	Eukaryotes	39	0.38	Binding ≤ 10μM
GSK3B-1-E	Glycogen Synthase Kinase-3 Beta (cluster #1 Of 7), Eukaryotic	Eukaryotes	1700	0.30	Binding ≤ 10μM
KC1AL-1-E	Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic	Eukaryotes	1700	0.30	Binding ≤ 10μM
KC1D-1-E	Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	37	0.39	Binding ≤ 10μM
KC1E-1-E	Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic	Eukaryotes	220	0.35	Binding ≤ 10μM
KS6A1-1-E	Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	320	0.34	Binding ≤ 10μM
KS6A6-1-E	Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.34	Binding ≤ 10μM
LCK-1-E	Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic	Eukaryotes	7800	0.26	Binding ≤ 10μM
M4K4-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3700	0.28	Binding ≤ 10μM
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	1200	0.31	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	95	0.36	Binding ≤ 10μM
MK10-2-E	C-Jun N-terminal Kinase 3 (cluster #2 Of 2), Eukaryotic	Eukaryotes	90	0.37	Binding ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	78	0.37	Binding ≤ 10μM
MK12-1-E	MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic	Eukaryotes	56	0.38	Binding ≤ 10μM
MK13-1-E	MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	56	0.38	Binding ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	72	0.37	Binding ≤ 10μM
MLTK-1-E	Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4400	0.28	Binding ≤ 10μM
MP2K2-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	9600	0.26	Binding ≤ 10μM
MRCKA-1-E	Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic	Eukaryotes	6200	0.27	Binding ≤ 10μM
MRCKB-1-E	Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	2700	0.29	Binding ≤ 10μM
MRCKG-1-E	Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	400	0.33	Binding ≤ 10μM
NLK-1-E	Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	25	0.39	Binding ≤ 10μM
PGH1-1-E	Cyclooxygenase-1 (cluster #1 Of 6), Eukaryotic	Eukaryotes	2000	0.30	Binding ≤ 10μM
PTK6-1-E	Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	9000	0.26	Binding ≤ 10μM
Q5SC61-1-E	Mitogen-activated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	100	0.36	Binding ≤ 10μM
RAF1-1-E	Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic	Eukaryotes	980	0.31	Binding ≤ 10μM
RIPK2-1-E	Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	24	0.40	Binding ≤ 10μM
SLK-1-E	Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	4600	0.28	Binding ≤ 10μM
SRC-1-E	Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic	Eukaryotes	5300	0.27	Binding ≤ 10μM
ST32B-1-E	Serine/threonine-protein Kinase 32B (cluster #1 Of 1), Eukaryotic	Eukaryotes	2100	0.29	Binding ≤ 10μM
STK36-1-E	Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic	Eukaryotes	860	0.31	Binding ≤ 10μM
TGFR1-1-E	TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic	Eukaryotes	7100	0.27	Binding ≤ 10μM
TGFR2-1-E	TGF-beta Receptor Type II (cluster #1 Of 1), Eukaryotic	Eukaryotes	1800	0.30	Binding ≤ 10μM
TNI3K-1-E	Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic	Eukaryotes	3500	0.28	Binding ≤ 10μM
TNIK-1-E	TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic	Eukaryotes	820	0.32	Binding ≤ 10μM
TTK-1-E	Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic	Eukaryotes	2500	0.29	Binding ≤ 10μM
TXK-1-E	Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic	Eukaryotes	4500	0.28	Binding ≤ 10μM
LOX5-1-E	Arachidonate 5-lipoxygenase (cluster #1 Of 7), Eukaryotic	Eukaryotes	80	0.37	Functional ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
MK12-1-E	MAP Kinase P38 Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
MK13-1-E	MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
TNFA-1-E	TNF-alpha (cluster #1 Of 2), Eukaryotic	Eukaryotes	70	0.37	Functional ≤ 10μM
Z100081-1-O	PBMC (Peripheral Blood Mononuclear Cells) (cluster #1 Of 4), Other	Other	80	0.37	Functional ≤ 10μM
Z102116-1-O	Toxoplasma Gondii RH (cluster #1 Of 2), Other	Other	8500	0.26	Functional ≤ 10μM
Z50472-1-O	Toxoplasma Gondii (cluster #1 Of 4), Other	Other	2500	0.29	Functional ≤ 10μM
Z50587-1-O	Homo Sapiens (cluster #1 Of 9), Other	Other	940	0.31	Functional ≤ 10μM
Z80523-1-O	SW1353 (cluster #1 Of 2), Other	Other	50	0.38	Functional ≤ 10μM
Z80548-1-O	THP-1 (Acute Monocytic Leukemia Cells) (cluster #1 Of 5), Other	Other	72	0.37	Functional ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.10	8.8	-21.46	1	4	0	59	377.444	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.10	9.25	-46.75	2	4	1	60	378.452	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.10	9.24	-46.38	2	4	1	60	378.452	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Molport

  • MolPort-020-313-396
  • MolPort-000-006-291

• Active BioPharma

  • 156
  • 113
  • 21

And 35 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ACV1B-1-E	Activin Receptor Type-1B (cluster #1 Of 1), Eukaryotic	Eukaryotes	3000	0.29	Binding ≤ 10μM
ADCK4-1-E	Uncharacterized AarF Domain-containing Protein Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3100	0.29	Binding ≤ 10μM
BRAF-1-E	Serine/threonine-protein Kinase B-raf (cluster #1 Of 1), Eukaryotic	Eukaryotes	710	0.32	Binding ≤ 10μM
CTRO-1-E	Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	420	0.33	Binding ≤ 10μM
DDR1-1-E	Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1000	0.31	Binding ≤ 10μM
DDR2-1-E	Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5000	0.27	Binding ≤ 10μM
EGFR-1-E	Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic	Eukaryotes	710	0.32	Binding ≤ 10μM
EPHA6-1-E	Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1200	0.31	Binding ≤ 10μM
EPHB2-1-E	Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7800	0.26	Binding ≤ 10μM
FRK-1-E	Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	4400	0.28	Binding ≤ 10μM
GAK-1-E	Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic	Eukaryotes	39	0.38	Binding ≤ 10μM
GSK3B-1-E	Glycogen Synthase Kinase-3 Beta (cluster #1 Of 7), Eukaryotic	Eukaryotes	1700	0.30	Binding ≤ 10μM
KC1AL-1-E	Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic	Eukaryotes	1700	0.30	Binding ≤ 10μM
KC1D-1-E	Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	37	0.39	Binding ≤ 10μM
KC1E-1-E	Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic	Eukaryotes	220	0.35	Binding ≤ 10μM
KS6A1-1-E	Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	320	0.34	Binding ≤ 10μM
KS6A6-1-E	Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.34	Binding ≤ 10μM
LCK-1-E	Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic	Eukaryotes	7800	0.26	Binding ≤ 10μM
M4K4-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3700	0.28	Binding ≤ 10μM
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	1200	0.31	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	95	0.36	Binding ≤ 10μM
MK10-2-E	C-Jun N-terminal Kinase 3 (cluster #2 Of 2), Eukaryotic	Eukaryotes	90	0.37	Binding ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	78	0.37	Binding ≤ 10μM
MK12-1-E	MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic	Eukaryotes	56	0.38	Binding ≤ 10μM
MK13-1-E	MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	56	0.38	Binding ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	72	0.37	Binding ≤ 10μM
MLTK-1-E	Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4400	0.28	Binding ≤ 10μM
MP2K2-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	9600	0.26	Binding ≤ 10μM
MRCKA-1-E	Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic	Eukaryotes	6200	0.27	Binding ≤ 10μM
MRCKB-1-E	Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	2700	0.29	Binding ≤ 10μM
MRCKG-1-E	Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	400	0.33	Binding ≤ 10μM
NLK-1-E	Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	25	0.39	Binding ≤ 10μM
PGH1-1-E	Cyclooxygenase-1 (cluster #1 Of 6), Eukaryotic	Eukaryotes	2000	0.30	Binding ≤ 10μM
PTK6-1-E	Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	9000	0.26	Binding ≤ 10μM
Q5SC61-1-E	Mitogen-activated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	100	0.36	Binding ≤ 10μM
RAF1-1-E	Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic	Eukaryotes	980	0.31	Binding ≤ 10μM
RIPK2-1-E	Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	24	0.40	Binding ≤ 10μM
SLK-1-E	Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	4600	0.28	Binding ≤ 10μM
SRC-1-E	Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic	Eukaryotes	5300	0.27	Binding ≤ 10μM
ST32B-1-E	Serine/threonine-protein Kinase 32B (cluster #1 Of 1), Eukaryotic	Eukaryotes	2100	0.29	Binding ≤ 10μM
STK36-1-E	Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic	Eukaryotes	860	0.31	Binding ≤ 10μM
TGFR1-1-E	TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic	Eukaryotes	7100	0.27	Binding ≤ 10μM
TGFR2-1-E	TGF-beta Receptor Type II (cluster #1 Of 1), Eukaryotic	Eukaryotes	1800	0.30	Binding ≤ 10μM
TNI3K-1-E	Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic	Eukaryotes	3500	0.28	Binding ≤ 10μM
TNIK-1-E	TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic	Eukaryotes	820	0.32	Binding ≤ 10μM
TTK-1-E	Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic	Eukaryotes	2500	0.29	Binding ≤ 10μM
TXK-1-E	Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic	Eukaryotes	4500	0.28	Binding ≤ 10μM
LOX5-1-E	Arachidonate 5-lipoxygenase (cluster #1 Of 7), Eukaryotic	Eukaryotes	80	0.37	Functional ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
MK12-1-E	MAP Kinase P38 Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
MK13-1-E	MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	940	0.31	Functional ≤ 10μM
TNFA-1-E	TNF-alpha (cluster #1 Of 2), Eukaryotic	Eukaryotes	70	0.37	Functional ≤ 10μM
Z100081-1-O	PBMC (Peripheral Blood Mononuclear Cells) (cluster #1 Of 4), Other	Other	80	0.37	Functional ≤ 10μM
Z102116-1-O	Toxoplasma Gondii RH (cluster #1 Of 2), Other	Other	8500	0.26	Functional ≤ 10μM
Z50472-1-O	Toxoplasma Gondii (cluster #1 Of 4), Other	Other	2500	0.29	Functional ≤ 10μM
Z50587-1-O	Homo Sapiens (cluster #1 Of 9), Other	Other	940	0.31	Functional ≤ 10μM
Z80523-1-O	SW1353 (cluster #1 Of 2), Other	Other	50	0.38	Functional ≤ 10μM
Z80548-1-O	THP-1 (Acute Monocytic Leukemia Cells) (cluster #1 Of 5), Other	Other	72	0.37	Functional ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.10	8.81	-16.64	1	4	0	59	377.444	4	↓ MOL2 SDF SMILES Flexibase
Ref Reference (pH 7)	3.10	8.8	-16.98	1	4	0	59	377.444	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.10	9.25	-46.22	2	4	1	60	378.452	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• American Custom Chemicals Corp.

  • CHM0293107

• Chembo Pharma

  • KB-76269

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	9	0.45	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	17	0.44	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	16	0.44	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.48	5.14	-12.21	3	7	0	96	343.431	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• American Custom Chemicals Corp.

  • CHM0293107

• Chembo Pharma

  • KB-76269

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	9	0.45	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	17	0.44	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	16	0.44	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.48	5.14	-12.28	3	7	0	96	343.431	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Toronto Research Chemicals

  • P167502
  • P167500

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
KC1E-1-E	Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic	Eukaryotes	260	0.32	Binding ≤ 10μM
KS6A3-1-E	Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	300	0.31	Binding ≤ 10μM
KS6A4-1-E	Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	150	0.33	Binding ≤ 10μM
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	190	0.32	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	16	0.38	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	19	0.37	Binding ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	120	0.33	Binding ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	14	0.38	Binding ≤ 10μM
NLK-1-E	Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	170	0.33	Binding ≤ 10μM
Z50597-1-O	Rattus Norvegicus (cluster #1 Of 12), Other	Other	50	0.35	Functional ≤ 10μM
Z80548-1-O	THP-1 (Acute Monocytic Leukemia Cells) (cluster #1 Of 5), Other	Other	25	0.37	Functional ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.17	5.26	-18.08	3	8	0	110	406.389	8	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• American Custom Chemicals Corp.

  • CHM0293108

• Chembo Pharma

  • KB-76270

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	3	0.41	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	6	0.40	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	5	0.40	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	10.7	-10.1	2	7	0	79	392.507	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.77	10.82	-37.48	3	7	1	80	393.515	6	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Molport

  • MolPort-002-883-541

• KeyOrganics

  • 9R-0253

• Mcule

  • MCULE-6411096648

• Ambinter

  • Amb2441282

• Mcule Make-on-demand

  • MCULE-6411096648

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	10000	0.30	Binding ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	6310	0.32	Binding ≤ 10μM
MK14-2-E	MAP Kinase P38 Alpha (cluster #2 Of 3), Eukaryotic	Eukaryotes	631	0.38	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	6.65	-16.85	2	5	0	75	308.337	5	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• AK Scientific

  • SYN1101

• Chembo Pharma

  • KB-80225
  • KB-80224

• Molport BB

  • MolPort-028-720-426

• Ryan Scientific BB

  • 048-08229

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ADCK3-1-E	Chaperone Activity Of Bc1 Complex-like, Mitochondrial (cluster #1 Of 1), Eukaryotic	Eukaryotes	320	0.32	Binding ≤ 10μM
DDR1-1-E	Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	270	0.33	Binding ≤ 10μM
GAK-1-E	Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic	Eukaryotes	680	0.31	Binding ≤ 10μM
KS6A3-1-E	Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	150	0.34	Binding ≤ 10μM
KS6A4-1-E	Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	73	0.36	Binding ≤ 10μM
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	29	0.38	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	9	0.40	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3	0.43	Binding ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	29	0.38	Binding ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	10	0.40	Binding ≤ 10μM
NLK-1-E	Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.41	Binding ≤ 10μM
STK36-1-E	Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic	Eukaryotes	330	0.32	Binding ≤ 10μM
Z50597-1-O	Rattus Norvegicus (cluster #1 Of 12), Other	Other	30	0.38	Functional ≤ 10μM
Z80548-1-O	THP-1 (Acute Monocytic Leukemia Cells) (cluster #1 Of 5), Other	Other	47	0.37	Functional ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	9.87	-13.02	1	7	0	78	388.374	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Vitas-M

  • STL089661

• eMolecules

  • 9868497

• Molport

  • MolPort-003-183-608

• ChemBridge

  • 5940634

• Enamine

  • Z27655988

And 7 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	2100	0.33	Binding ≤ 10μM
MK10-2-E	C-Jun N-terminal Kinase 3 (cluster #2 Of 2), Eukaryotic	Eukaryotes	1700	0.34	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.38	2.09	-10.93	1	4	0	55	319.36	5	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• UORSY Make-on-demand

  • PB169741868

• AKOS (make-on-demand)

  • AKOS001207770

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	2000	0.35	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	6900	0.31	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.48	8.07	-10.3	1	4	0	55	343.326	6	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Mcule

  • MCULE-7266220057

• UORSY

  • PB109169894

• Mcule Make-on-demand

  • MCULE-7266220057

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	600	0.38	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3900	0.33	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	9.3	-11.07	1	4	0	55	325.389	5	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• eMolecules

  • 18914628

• Enamine

  • Z109088640

• Mcule

  • MCULE-8142698091

• Ambinter

  • Amb7842184

• Mcule Make-on-demand

  • MCULE-8142698091

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	400	0.39	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1500	0.35	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.74	9.19	-11.09	1	4	0	55	325.389	5	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• eMolecules

  • 5808531

• Molport

  • MolPort-002-899-047

• Maybridge

  • GK01981

• Mcule

  • MCULE-1255934042

• UORSY

  • PB109166130

And 4 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	1800	0.45	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	2200	0.44	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.48	-0.06	-9.91	1	4	0	55	281.358	5	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Enamine BB Make on Demand

  • BBV-27049446

• UORSY BB Make-on-demand

  • BBV-27049446

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	6600	0.38	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	5.13	-10.98	1	5	0	68	276.317	5	↓ MOL2 SDF SMILES Flexibase

Analogs

12325075

Draw Identity 99% 90% 80% 70%

Vendors

• Specs

  • AP-970/42896749

• Vitas-M

  • STK344452

• eMolecules

  • 1570714

• Molport

  • MolPort-002-278-961

• ChemBridge

  • 7912510

And 6 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	360	0.38	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1100	0.35	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.97	9.63	-36.05	2	5	1	50	413.723	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.97	7.42	-4.14	1	5	0	49	412.715	4	↓ MOL2 SDF SMILES Flexibase

Analogs

4095791

12501465

Draw Identity 99% 90% 80% 70%

Vendors

• Acros Organics

  • 32853

• Angene Building Blocks

  • AGN-PC-0T6SZQ

• Boerchem Pharmatech BB

  • BC649925

• Selleck Chemicals

  • S1421

• Tocris

  • 1570

And 3 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
AAK1-1-E	Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
AAPK1-1-E	AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
AAPK2-1-E	AMP-activated Protein Kinase, Alpha-2 Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	12	0.32	Binding ≤ 10μM
ABL1-1-E	Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic	Eukaryotes	91	0.28	Binding ≤ 10μM
ABL2-1-E	Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	160	0.27	Binding ≤ 10μM
ACK1-1-E	Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	17	0.31	Binding ≤ 10μM
ACV1B-1-E	Activin Receptor Type-1B (cluster #1 Of 1), Eukaryotic	Eukaryotes	680	0.25	Binding ≤ 10μM
ACVR1-1-E	Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	470	0.25	Binding ≤ 10μM
AKT1-2-E	RAC-alpha Serine/threonine-protein Kinase (cluster #2 Of 3), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
AKT2-2-E	Serine/threonine-protein Kinase AKT2 (cluster #2 Of 2), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
AKT3-2-E	Serine/threonine-protein Kinase AKT3 (cluster #2 Of 2), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
ALK-1-E	ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	32	0.30	Binding ≤ 10μM
ANKK1-1-E	Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	270	0.26	Binding ≤ 10μM
AURKA-1-E	Serine/threonine-protein Kinase Aurora-A (cluster #1 Of 3), Eukaryotic	Eukaryotes	22	0.31	Binding ≤ 10μM
AURKB-1-E	Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic	Eukaryotes	19	0.31	Binding ≤ 10μM
AURKC-1-E	Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic	Eukaryotes	23	0.31	Binding ≤ 10μM
AVR2B-1-E	Activin Receptor Type-2B (cluster #1 Of 1), Eukaryotic	Eukaryotes	4600	0.21	Binding ≤ 10μM
BLK-1-E	Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	15	0.31	Binding ≤ 10μM
BMP2K-1-E	BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
BMR1A-1-E	Bone Morphogenetic Protein Receptor Type-1A (cluster #1 Of 1), Eukaryotic	Eukaryotes	3700	0.22	Binding ≤ 10μM
BMX-1-E	Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic	Eukaryotes	410	0.26	Binding ≤ 10μM
BRSK1-1-E	BR Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	26	0.30	Binding ≤ 10μM
BRSK2-1-E	BR Serine/threonine-protein Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
BTK-1-E	Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic	Eukaryotes	710	0.25	Binding ≤ 10μM
CCNB1-1-E	G2/mitotic-specific Cyclin B1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
CCNB2-1-E	G2/mitotic-specific Cyclin B2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
CCNB3-1-E	G2/mitotic-specific Cyclin B3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
CCNE1-1-E	G1/S-specific Cyclin E1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	20	0.31	Binding ≤ 10μM
CCNE2-1-E	G1/S-specific Cyclin E2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	20	0.31	Binding ≤ 10μM
CDK1-1-E	Cyclin-dependent Kinase 1 (cluster #1 Of 4), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
CDK14-1-E	Serine/threonine-protein Kinase PFTAIRE-1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	160	0.27	Binding ≤ 10μM
CDK16-1-E	Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	25	0.30	Binding ≤ 10μM
CDK17-1-E	Serine/threonine-protein Kinase PCTAIRE-2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	96	0.28	Binding ≤ 10μM
CDK18-1-E	Serine/threonine-protein Kinase PCTAIRE-3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	270	0.26	Binding ≤ 10μM
CDK19-1-E	Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	190	0.27	Binding ≤ 10μM
CDK2-1-E	Cyclin-dependent Kinase 2 (cluster #1 Of 5), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
CDK3-1-E	Cyclin-dependent Kinase 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
CDK4-2-E	Cyclin-dependent Kinase 4 (cluster #2 Of 3), Eukaryotic	Eukaryotes	18	0.31	Binding ≤ 10μM
CDK5-1-E	Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	89	0.28	Binding ≤ 10μM
CDK6-1-E	Cyclin-dependent Kinase 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	116	0.28	Binding ≤ 10μM
CDK7-1-E	Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	45	0.29	Binding ≤ 10μM
CDK8-1-E	Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic	Eukaryotes	510	0.25	Binding ≤ 10μM
CDK9-1-E	Cyclin-dependent Kinase 9 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
CHK1-1-E	Serine/threonine-protein Kinase Chk1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	10	0.32	Binding ≤ 10μM
CHK2-1-E	Serine/threonine-protein Kinase Chk2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
CLK1-2-E	Dual Specificty Protein Kinase CLK1 (cluster #2 Of 2), Eukaryotic	Eukaryotes	32	0.30	Binding ≤ 10μM
CLK2-1-E	Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
CLK3-1-E	Dual Specificity Protein Kinase CLK3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	910	0.24	Binding ≤ 10μM
CLK4-1-E	Dual Specificity Protein Kinase CLK4 (cluster #1 Of 2), Eukaryotic	Eukaryotes	10	0.32	Binding ≤ 10μM
CSF1R-1-E	Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	12	0.32	Binding ≤ 10μM
CSK-1-E	Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic	Eukaryotes	440	0.25	Binding ≤ 10μM
CSK21-1-E	Casein Kinase II Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	7620	0.20	Binding ≤ 10μM
CSK22-1-E	Casein Kinase II Alpha (prime) (cluster #1 Of 2), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
CSK2B-1-E	Casein Kinase II Beta (cluster #1 Of 3), Eukaryotic	Eukaryotes	7000	0.21	Binding ≤ 10μM
CTRO-1-E	Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	340	0.26	Binding ≤ 10μM
DAPK1-1-E	Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
DAPK2-1-E	Death-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
DAPK3-1-E	Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1500	0.23	Binding ≤ 10μM
DCLK1-1-E	Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	110	0.28	Binding ≤ 10μM
DCLK2-1-E	Serine/threonine-protein Kinase DCLK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	73	0.29	Binding ≤ 10μM
DCLK3-1-E	Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	17	0.31	Binding ≤ 10μM
DDR1-1-E	Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	19	0.31	Binding ≤ 10μM
DDR2-1-E	Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	42	0.30	Binding ≤ 10μM
DMPK-1-E	Myotonin-protein Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
DYR1B-1-E	Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic	Eukaryotes	28	0.30	Binding ≤ 10μM
E2AK2-1-E	Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	100	0.28	Binding ≤ 10μM
E2AK2-1-E	Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	360	0.26	Binding ≤ 10μM
E2AK4-1-E	Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	16	0.31	Binding ≤ 10μM
EGFR-1-E	Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic	Eukaryotes	96	0.28	Binding ≤ 10μM
EPHA1-1-E	Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	300	0.26	Binding ≤ 10μM
EPHA2-1-E	Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	870	0.24	Binding ≤ 10μM
EPHA3-1-E	Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	55	0.29	Binding ≤ 10μM
EPHA4-1-E	Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	710	0.25	Binding ≤ 10μM
EPHA5-1-E	Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	95	0.28	Binding ≤ 10μM
EPHA6-1-E	Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	290	0.26	Binding ≤ 10μM
EPHA7-1-E	Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	690	0.25	Binding ≤ 10μM
EPHA8-1-E	Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic	Eukaryotes	300	0.26	Binding ≤ 10μM
EPHB1-1-E	Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	590	0.25	Binding ≤ 10μM
EPHB2-1-E	Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2100	0.23	Binding ≤ 10μM
EPHB4-1-E	Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	233	0.27	Binding ≤ 10μM
ERBB4-1-E	Receptor Protein-tyrosine Kinase ErbB-4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	282	0.26	Binding ≤ 10μM
FAK1-1-E	Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	68	0.29	Binding ≤ 10μM
FAK2-1-E	Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
FER-1-E	Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic	Eukaryotes	30	0.30	Binding ≤ 10μM
FES-1-E	Tyrosine-protein Kinase FES (cluster #1 Of 1), Eukaryotic	Eukaryotes	23	0.31	Binding ≤ 10μM
FGFR1-1-E	Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	90	0.28	Binding ≤ 10μM
FGFR2-1-E	Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	420	0.26	Binding ≤ 10μM
FGFR3-1-E	Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	88	0.28	Binding ≤ 10μM
FGFR4-1-E	Fibroblast Growth Factor Receptor 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	420	0.26	Binding ≤ 10μM
FGR-1-E	Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic	Eukaryotes	30	0.30	Binding ≤ 10μM
FLT3-1-E	Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
FRK-1-E	Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	45	0.29	Binding ≤ 10μM
FYN-1-E	Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic	Eukaryotes	83	0.28	Binding ≤ 10μM
GAK-1-E	Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic	Eukaryotes	68	0.29	Binding ≤ 10μM
GSK3A-1-E	Glycogen Synthase Kinase-3 Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	140	0.27	Binding ≤ 10μM
GSK3B-1-E	Glycogen Synthase Kinase-3 Beta (cluster #1 Of 7), Eukaryotic	Eukaryotes	89	0.28	Binding ≤ 10μM
HCK-1-E	Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic	Eukaryotes	20	0.31	Binding ≤ 10μM
HIPK1-1-E	Homeodomain-interacting Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2639	0.22	Binding ≤ 10μM
IGF1R-1-E	Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	35	0.30	Binding ≤ 10μM
IKKA-2-E	Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit (cluster #2 Of 3), Eukaryotic	Eukaryotes	39	0.30	Binding ≤ 10μM
IKKB-1-E	Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	771	0.24	Binding ≤ 10μM
IKKE-1-E	Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
INSR-1-E	Insulin Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	200	0.27	Binding ≤ 10μM
INSRR-1-E	Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic	Eukaryotes	81	0.28	Binding ≤ 10μM
IRAK3-1-E	Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	13	0.32	Binding ≤ 10μM
IRAK4-1-E	Interleukin-1 Receptor-associated Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	34	0.30	Binding ≤ 10μM
ITK-1-E	Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic	Eukaryotes	19	0.31	Binding ≤ 10μM
JAK2-1-E	Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
JAK3-1-E	Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
KAP2-1-E	CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	100	0.28	Binding ≤ 10μM
KAPCA-1-E	CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 4), Eukaryotic	Eukaryotes	27	0.30	Binding ≤ 10μM
KAPCB-1-E	CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
KAPCG-1-E	CAMP-dependent Protein Kinase, Gamma Catalytic Subunit (cluster #1 Of 2), Eukaryotic	Eukaryotes	80	0.28	Binding ≤ 10μM
KC1A-1-E	Casein Kinase I Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	1400	0.23	Binding ≤ 10μM
KC1AL-1-E	Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.26	Binding ≤ 10μM
KC1D-1-E	Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	1400	0.23	Binding ≤ 10μM
KC1E-1-E	Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic	Eukaryotes	1400	0.23	Binding ≤ 10μM
KC1G1-1-E	Casein Kinase I Gamma 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1400	0.23	Binding ≤ 10μM
KC1G2-1-E	Casein Kinase I Gamma 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	780	0.24	Binding ≤ 10μM
KCC1A-1-E	CaM Kinase I Alpha (cluster #1 Of 2), Eukaryotic	Eukaryotes	40	0.30	Binding ≤ 10μM
KCC1D-1-E	CaM Kinase I Delta (cluster #1 Of 2), Eukaryotic	Eukaryotes	2	0.35	Binding ≤ 10μM
KCC1G-1-E	CaM Kinase I Gamma (cluster #1 Of 2), Eukaryotic	Eukaryotes	53	0.29	Binding ≤ 10μM
KCC2A-1-E	CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
KCC2B-1-E	CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
KCC2D-1-E	CaM Kinase II Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
KCC2G-1-E	CaM Kinase II Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
KCC4-1-E	CaM Kinase IV (cluster #1 Of 1), Eukaryotic	Eukaryotes	41	0.30	Binding ≤ 10μM
KGP1-1-E	CGMP-dependent Protein Kinase 1 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	32	0.30	Binding ≤ 10μM
KGP2-1-E	CGMP-dependent Protein Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	16	0.31	Binding ≤ 10μM
KIT-1-E	Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	10	0.32	Binding ≤ 10μM
KKCC1-1-E	CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
KKCC2-1-E	CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
KPB1-1-E	Phosphorylase Kinase Alpha M Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
KPB2-1-E	Phosphorylase Kinase Alpha L Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
KPBB-1-E	Phosphorylase Kinase Beta Subunit (cluster #1 Of 2), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
KPCA-1-E	Protein Kinase C Alpha (cluster #1 Of 6), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KPCB-1-E	Protein Kinase C Beta (cluster #1 Of 4), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
KPCD-1-E	Protein Kinase C Delta (cluster #1 Of 4), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KPCD1-1-E	Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KPCD2-1-E	Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	72	0.29	Binding ≤ 10μM
KPCD3-1-E	Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KPCE-1-E	Protein Kinase C Epsilon (cluster #1 Of 5), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KPCG-1-E	Protein Kinase C Gamma (cluster #1 Of 4), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
KPCI-1-E	Protein Kinase C Iota (cluster #1 Of 3), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KPCL-2-E	Protein Kinase C Eta (cluster #2 Of 4), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
KPCT-1-E	Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
KPCZ-1-E	Protein Kinase C Zeta (cluster #1 Of 5), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
KS6A1-1-E	Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
KS6A2-1-E	Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
KS6A3-1-E	Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	69	0.29	Binding ≤ 10μM
KS6A4-1-E	Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
KS6A5-1-E	Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic	Eukaryotes	890	0.24	Binding ≤ 10μM
KS6A6-1-E	Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
KS6B1-1-E	Ribosomal Protein S6 Kinase 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
KS6B2-1-E	Ribosomal Protein S6 Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
KSYK-1-E	Tyrosine-protein Kinase SYK (cluster #1 Of 2), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
LATS1-1-E	Serine/threonine-protein Kinase LATS1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	42	0.30	Binding ≤ 10μM
LATS2-1-E	Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	17	0.31	Binding ≤ 10μM
LCK-1-E	Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
LIMK1-1-E	LIM Domain Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	690	0.25	Binding ≤ 10μM
LIMK2-1-E	LIM Domain Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	9200	0.20	Binding ≤ 10μM
LTK-1-E	Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	37	0.30	Binding ≤ 10μM
LYN-1-E	Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic	Eukaryotes	40	0.30	Binding ≤ 10μM
M3K10-1-E	Mitogen-activated Protein Kinase Kinase Kinase 10 (cluster #1 Of 1), Eukaryotic	Eukaryotes	52	0.29	Binding ≤ 10μM
M3K11-1-E	Mitogen-activated Protein Kinase Kinase Kinase 11 (cluster #1 Of 1), Eukaryotic	Eukaryotes	20	0.31	Binding ≤ 10μM
M3K14-1-E	Mitogen-activated Protein Kinase Kinase Kinase 14 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2300	0.23	Binding ≤ 10μM
M3K4-1-E	Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2200	0.23	Binding ≤ 10μM
M3K5-1-E	Mitogen-activated Protein Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	37	0.30	Binding ≤ 10μM
M3K7-1-E	Mitogen-activated Protein Kinase Kinase Kinase 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	35	0.30	Binding ≤ 10μM
M3K9-1-E	Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic	Eukaryotes	10	0.32	Binding ≤ 10μM
M4K1-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
M4K3-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
M4K4-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic	Eukaryotes	24	0.30	Binding ≤ 10μM
M4K5-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	26	0.30	Binding ≤ 10μM
MAPK2-1-E	MAP Kinase-activated Protein Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	880	0.24	Binding ≤ 10μM
MARK1-1-E	Serine/threonine-protein Kinase MARK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
MARK2-1-E	MAP/microtubule Affinity-regulating Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
MARK3-1-E	Serine/threonine-protein Kinase C-TAK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
MARK4-1-E	MAP/microtubule Affinity-regulating Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
MELK-1-E	Maternal Embryonic Leucine Zipper Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	33	0.30	Binding ≤ 10μM
MERTK-1-E	Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
MET-1-E	Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	190	0.27	Binding ≤ 10μM
MINK1-1-E	Misshapen-like Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
MK01-1-E	Mitogen-activated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7300	0.21	Binding ≤ 10μM
MK03-1-E	MAP Kinase ERK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	8400	0.20	Binding ≤ 10μM
MK07-1-E	Mitogen-activated Protein Kinase 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1600	0.23	Binding ≤ 10μM
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	520	0.25	Binding ≤ 10μM
MK09-1-E	C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic	Eukaryotes	1100	0.24	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	340	0.26	Binding ≤ 10μM
MK11-1-E	MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	1000	0.24	Binding ≤ 10μM
MK12-1-E	MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic	Eukaryotes	92	0.28	Binding ≤ 10μM
MK13-1-E	MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic	Eukaryotes	1000	0.24	Binding ≤ 10μM
MK14-1-E	MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic	Eukaryotes	1000	0.24	Binding ≤ 10μM
MK15-1-E	Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic	Eukaryotes	35	0.30	Binding ≤ 10μM
MKNK1-1-E	MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	170	0.27	Binding ≤ 10μM
MKNK2-1-E	MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	22	0.31	Binding ≤ 10μM
MP2K1-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic	Eukaryotes	670	0.25	Binding ≤ 10μM
MP2K2-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	28	0.30	Binding ≤ 10μM
MP2K3-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.33	Binding ≤ 10μM
MP2K4-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	70	0.29	Binding ≤ 10μM
MP2K6-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
MRCKA-1-E	Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic	Eukaryotes	57	0.29	Binding ≤ 10μM
MRCKB-1-E	Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	42	0.30	Binding ≤ 10μM
MRCKG-1-E	Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	37	0.30	Binding ≤ 10μM
MST4-1-E	Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	140	0.27	Binding ≤ 10μM
MUSK-1-E	Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	86	0.28	Binding ≤ 10μM
MYLK-1-E	Myosin Light Chain Kinase, Smooth Muscle (cluster #1 Of 1), Eukaryotic	Eukaryotes	40	0.30	Binding ≤ 10μM
MYLK2-1-E	Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	61	0.29	Binding ≤ 10μM
MYLK4-1-E	Myosin Light Chain Kinase Family Member 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	470	0.25	Binding ≤ 10μM
MYO3A-1-E	Myosin IIIA (cluster #1 Of 1), Eukaryotic	Eukaryotes	500	0.25	Binding ≤ 10μM
MYO3B-1-E	Myosin-IIIB (cluster #1 Of 1), Eukaryotic	Eukaryotes	300	0.26	Binding ≤ 10μM
NEK1-1-E	Serine/threonine-protein Kinase Nek1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	860	0.24	Binding ≤ 10μM
NEK2-1-E	Serine/threonine-protein Kinase NEK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	750	0.24	Binding ≤ 10μM
NEK5-1-E	Serine/threonine-protein Kinase Nek5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	810	0.24	Binding ≤ 10μM
NEK7-1-E	Serine/threonine-protein Kinase NEK7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4500	0.21	Binding ≤ 10μM
NEK9-1-E	Serine/threonine-protein Kinase NEK9 (cluster #1 Of 1), Eukaryotic	Eukaryotes	6700	0.21	Binding ≤ 10μM
NLK-1-E	Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	220	0.27	Binding ≤ 10μM
NTRK1-1-E	Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
NTRK2-1-E	Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
NTRK3-1-E	NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	17	0.31	Binding ≤ 10μM
NUAK1-1-E	NUAK Family SNF1-like Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.34	Binding ≤ 10μM
NUAK2-1-E	NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
P90584-2-E	Protein Kinase Pfmrk (cluster #2 Of 2), Eukaryotic	Eukaryotes	4000	0.22	Binding ≤ 10μM
PAK1-1-E	Serine/threonine-protein Kinase PAK 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2	0.35	Binding ≤ 10μM
PAK2-1-E	Serine/threonine-protein Kinase PAK 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PAK3-1-E	Serine/threonine-protein Kinase PAK 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
PAK4-1-E	Serine/threonine-protein Kinase PAK 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
PAK6-1-E	Serine/threonine-protein Kinase PAK6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
PAK7-1-E	Serine/threonine-protein Kinase PAK7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PDPK1-1-E	3-phosphoinositide Dependent Protein Kinase-1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	2	0.35	Binding ≤ 10μM
PGFRA-1-E	Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic	Eukaryotes	2	0.35	Binding ≤ 10μM
PGFRB-1-E	Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PHKG1-1-E	Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PHKG2-1-E	Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PI42B-1-E	Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	77	0.28	Binding ≤ 10μM
PI51A-1-E	Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	43	0.29	Binding ≤ 10μM
PIM1-1-E	Serine/threonine-protein Kinase PIM1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	8	0.32	Binding ≤ 10μM
PIM2-1-E	Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
PIM3-1-E	Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
PKN1-1-E	Protein Kinase N1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
PKN2-1-E	Protein Kinase N2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PLK1-1-E	Serine/threonine-protein Kinase PLK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	190	0.27	Binding ≤ 10μM
PLK2-1-E	Serine/threonine-protein Kinase PLK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	197	0.27	Binding ≤ 10μM
PLK3-1-E	Serine/threonine-protein Kinase PLK3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	910	0.24	Binding ≤ 10μM
PLK4-1-E	Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
PRKX-1-E	Serine/threonine-protein Kinase PRKX (cluster #1 Of 1), Eukaryotic	Eukaryotes	13	0.32	Binding ≤ 10μM
PTK6-1-E	Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	2300	0.23	Binding ≤ 10μM
Q95J97-1-E	CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	80	0.28	Binding ≤ 10μM
RAF1-1-E	Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
RET-1-E	Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic	Eukaryotes	28	0.30	Binding ≤ 10μM
RIOK1-1-E	Serine/threonine-protein Kinase RIO1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	130	0.28	Binding ≤ 10μM
RIOK3-1-E	Serine/threonine-protein Kinase RIO3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	76	0.28	Binding ≤ 10μM
RIPK2-1-E	Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5200	0.21	Binding ≤ 10μM
ROCK1-1-E	Rho-associated Protein Kinase 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
ROS1-1-E	Proto-oncogene Tyrosine-protein Kinase ROS (cluster #1 Of 1), Eukaryotic	Eukaryotes	30	0.30	Binding ≤ 10μM
SIK1-1-E	Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2	0.35	Binding ≤ 10μM
SIK2-1-E	Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.36	Binding ≤ 10μM
SLK-1-E	Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
SRC-1-E	Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic	Eukaryotes	86	0.28	Binding ≤ 10μM
SRMS-1-E	Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic	Eukaryotes	740	0.25	Binding ≤ 10μM
SRPK1-1-E	Serine/threonine-protein Kinase SRPK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
SRPK2-1-E	Serine/threonine-protein Kinase SRPK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	67	0.29	Binding ≤ 10μM
ST17A-1-E	Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic	Eukaryotes	23	0.31	Binding ≤ 10μM
ST17B-1-E	Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic	Eukaryotes	26	0.30	Binding ≤ 10μM
ST32B-1-E	Serine/threonine-protein Kinase 32B (cluster #1 Of 1), Eukaryotic	Eukaryotes	98	0.28	Binding ≤ 10μM
ST32C-1-E	Serine/threonine-protein Kinase 32C (cluster #1 Of 1), Eukaryotic	Eukaryotes	310	0.26	Binding ≤ 10μM
ST38L-1-E	Serine/threonine-protein Kinase 38-like (cluster #1 Of 2), Eukaryotic	Eukaryotes	77	0.28	Binding ≤ 10μM
STK10-1-E	Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
STK11-1-E	Serine/threonine-protein Kinase 11 (cluster #1 Of 1), Eukaryotic	Eukaryotes	61	0.29	Binding ≤ 10μM
STK16-1-E	Serine/threonine-protein Kinase 16 (cluster #1 Of 1), Eukaryotic	Eukaryotes	270	0.26	Binding ≤ 10μM
STK24-1-E	Serine/threonine-protein Kinase 24 (cluster #1 Of 1), Eukaryotic	Eukaryotes	120	0.28	Binding ≤ 10μM
STK25-1-E	Serine/threonine-protein Kinase 25 (cluster #1 Of 1), Eukaryotic	Eukaryotes	110	0.28	Binding ≤ 10μM
STK3-1-E	Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
STK33-1-E	Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic	Eukaryotes	2	0.35	Binding ≤ 10μM
STK36-1-E	Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic	Eukaryotes	6700	0.21	Binding ≤ 10μM
STK4-1-E	Serine/threonine-protein Kinase MST1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
SYK-1-E	Lysyl-tRNA Synthetase (cluster #1 Of 1), Eukaryotic	Eukaryotes	9	0.32	Binding ≤ 10μM
TAB1-1-E	Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	35	0.30	Binding ≤ 10μM
TBA1A-1-E	Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic	Eukaryotes	770	0.24	Binding ≤ 10μM
TEC-1-E	Tyrosine-protein Kinase TEC (cluster #1 Of 1), Eukaryotic	Eukaryotes	1300	0.24	Binding ≤ 10μM
TESK1-1-E	Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	320	0.26	Binding ≤ 10μM
TGFR1-1-E	TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic	Eukaryotes	2000	0.23	Binding ≤ 10μM
TIE1-1-E	Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	65	0.29	Binding ≤ 10μM
TIE2-1-E	Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	52	0.29	Binding ≤ 10μM
TLK1-1-E	Serine/threonine-protein Kinase Tousled-like 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	27	0.30	Binding ≤ 10μM
TLK2-1-E	Serine/threonine-protein Kinase Tousled-like 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	16	0.31	Binding ≤ 10μM
TNI3K-1-E	Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic	Eukaryotes	1000	0.24	Binding ≤ 10μM
TNIK-1-E	TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.33	Binding ≤ 10μM
TNK1-1-E	Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
TSSK1-1-E	Testis-specific Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	24	0.30	Binding ≤ 10μM
TTK-1-E	Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic	Eukaryotes	61	0.29	Binding ≤ 10μM
TXK-1-E	Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic	Eukaryotes	230	0.27	Binding ≤ 10μM
TYK2-1-E	Tyrosine-protein Kinase TYK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	56	0.29	Binding ≤ 10μM
TYRO3-1-E	Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	49	0.29	Binding ≤ 10μM
UFO-1-E	Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.33	Binding ≤ 10μM
ULK3-1-E	Serine/threonine-protein Kinase ULK3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
VGFR1-1-E	Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	14	0.31	Binding ≤ 10μM
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	88	0.28	Binding ≤ 10μM
VGFR3-1-E	Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	14	0.31	Binding ≤ 10μM
WEE1-1-E	Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1600	0.23	Binding ≤ 10μM
YES-1-E	Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic	Eukaryotes	52	0.29	Binding ≤ 10μM
ZAP70-1-E	Tyrosine-protein Kinase ZAP-70 (cluster #1 Of 1), Eukaryotic	Eukaryotes	53	0.29	Binding ≤ 10μM
AKT1-1-E	Serine/threonine-protein Kinase AKT (cluster #1 Of 1), Eukaryotic	Eukaryotes	460	0.25	Functional ≤ 10μM
KPCB-1-E	Protein Kinase C Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	77	0.28	Functional ≤ 10μM
Z104294-1-O	Cyclin-dependent Kinase 5/CDK5 Activator 1 (cluster #1 Of 2), Other	Other	10	0.32	Binding ≤ 10μM
Z104295-1-O	Cyclin-dependent Kinase 4/cyclin D1 (cluster #1 Of 2), Other	Other	59	0.29	Binding ≤ 10μM
Z100081-2-O	PBMC (Peripheral Blood Mononuclear Cells) (cluster #2 Of 4), Other	Other	16	0.31	Functional ≤ 10μM
Z100201-1-O	Splenocytes (Spleen Cells) (cluster #1 Of 1), Other	Other	400	0.26	Functional ≤ 10μM
Z50425-3-O	Plasmodium Falciparum (cluster #3 Of 22), Other	Other	190	0.27	Functional ≤ 10μM
Z50512-1-O	Cavia Porcellus (cluster #1 Of 7), Other	Other	7500	0.20	Functional ≤ 10μM
Z80120-1-O	DLD-1 (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other	Other	9	0.32	Functional ≤ 10μM
Z80166-1-O	HT-29 (Colon Adenocarcinoma Cells) (cluster #1 Of 12), Other	Other	3	0.34	Functional ≤ 10μM
Z80211-1-O	LoVo (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other	Other	1	0.36	Functional ≤ 10μM
Z80224-1-O	MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other	Other	50	0.29	Functional ≤ 10μM
Z80800-1-O	MIA PaCa-2 (Pancreatic Carcinoma Cells) (cluster #1 Of 2), Other	Other	370	0.26	Functional ≤ 10μM
Z80928-1-O	HCT-116 (Colon Carcinoma Cells) (cluster #1 Of 9), Other	Other	6	0.33	Functional ≤ 10μM
Z80936-1-O	HEK293 (Embryonic Kidney Fibroblasts) (cluster #1 Of 4), Other	Other	77	0.28	Functional ≤ 10μM
Z81057-1-O	HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other	Other	4	0.34	Functional ≤ 10μM
Z81072-1-O	Jurkat (Acute Leukemic T-cells) (cluster #1 Of 10), Other	Other	71	0.29	Functional ≤ 10μM
Z81247-1-O	HeLa (Cervical Adenocarcinoma Cells) (cluster #1 Of 9), Other	Other	0	0.00	Functional ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	8.49	-39.52	3	7	1	74	467.549	2	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.89	8.85	-16.32	2	7	0	69	466.541	2	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• eMolecules

  • 29604795

• Molport

  • MolPort-003-431-339

• Enamine

  • Z29084246

• Mcule

  • MCULE-9520203849

• Life Chemicals BB Make-on-Demand

  • F2245-0229

And 2 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	3200	0.45	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.35	-3.53	-11.19	3	4	0	72	266.347	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

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Vendors

• Vitas-M

  • STK464275

• eMolecules

  • 2266103

• Molport

  • MolPort-001-614-817

• Alinda

  • IVK/4006042

• Life Chemicals

  • F1358-1003

And 6 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	1400	0.43	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	-2.8	-11.05	3	4	0	72	294.763	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• eMolecules

  • 12046018

• Molport

  • MolPort-003-158-228

• Life Chemicals

  • F2726-0893

• Mcule

  • MCULE-4294321193

• Ambinter

  • Amb5431544

And 1 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	5100	0.39	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.61	-1.91	-11.69	3	4	0	72	278.308	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Life Chemicals (Virtual)

  • F1358-0901

• Life Chemicals BB Make-on-Demand

  • F1358-0901

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	5400	0.39	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	3.88	-12.79	3	4	0	72	274.345	4	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Enamine

  • Z29084306

• Mcule

  • MCULE-4023024682

• Ambinter

  • Amb2287870

• Enamine BB Make on Demand

  • BBV-32462404

• Mcule Make-on-demand

  • MCULE-4023024682

And 1 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	9400	0.34	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	3.26	-16.69	4	5	0	88	299.355	4	↓ MOL2 SDF SMILES Flexibase

Analogs

624282

Draw Identity 99% 90% 80% 70%

Vendors

• Vitas-M

  • STK729606

• eMolecules

  • 17664146

• IBScreen

  • STOCK6S-65301

• Mcule

  • MCULE-4078471463

• Pharmeks

  • PHAR216122

And 6 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	360	0.39	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1200	0.36	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.59	-1.66	-36.64	2	5	1	50	399.696	3	↓ MOL2 SDF SMILES Flexibase

Analogs

Draw Identity 99% 90% 80% 70%

Vendors

• Vitas-M

  • STK319791

• eMolecules

  • 13582141

• Molport

  • MolPort-003-001-355

• ChemBridge

  • 9116398

• IBScreen

  • STOCK6S-33994

And 6 More

Activity (Go SEA)

Clustered Target Annotations

Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MK08-1-E	Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic	Eukaryotes	600	0.35	Binding ≤ 10μM
MK10-1-E	C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	810	0.34	Binding ≤ 10μM

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Ų)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.96	-2.41	-10.46	1	6	0	65	426.698	3	↓ MOL2 SDF SMILES Flexibase