| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 29th, 2005 | 35 | No |
Popular Name: staurosporine staurosporine
Find On: PubMed — Wikipedia — Google
CAS Number: 62996-74-1
(+)-Staurosporine; Staurosporin
62996-74-1; C02079; STS; Staurosporine
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.89 | 8.49 | -39.52 | 3 | 7 | 1 | 74 | 467.549 | 2 | ↓ |
| Hi High (pH 8-9.5) | 3.89 | 8.85 | -16.32 | 2 | 7 | 0 | 69 | 466.541 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Mp [°C] | 270 | Acros Organics |
| UniProt Database Links | AFK_PHYPO; ALK_HUMAN; ALK_MOUSE; AP1_SCHPO; CDK1_HUMAN; CDK2_HUMAN; DUS18_BOVIN; DUS18_MOUSE; DUS18_PONAB; DUS18_RAT; HMN10_HUMAN; HMN1_HUMAN; HMN2_HUMAN; HMN3_HUMAN; HMN4_HUMAN; HMN5_HUMAN; HMN6_HUMAN; HMN7_HUMAN; HMN8_HUMAN; HMN9_HUMAN; MAPK2_CRILO; MAP | ChEBI |
| Patent Database Links | EP1201668; EP1507005; EP1568379; EP1738759; US2005026984; US2005261263; US2006194294; US2007191338; US2007243225; US2007244040; US2007248955; US2007254853; US2008139493; US2008275023; US2008279913; WO2005047526; WO2005085196; WO2005123676; WO2006048296; W | ChEBI |
| H phrase | H351: Suspected of causing cancer | Acros Organics |
| P phrase | P281: Use personal protective equipment as required | Acros Organics |
| Target | PKC | Selleck Chemicals |
| R phrase | R40: Limited evidence of a carcinogenic effect. | Acros Organics |
| S phrase | S36/37: Wear suitable protective clothing and gloves. | Acros Organics |
| Hazard | XN: Harmful | Acros Organics |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AAK1-1-E | Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| AAPK1-1-E | AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| AAPK2-1-E | AMP-activated Protein Kinase, Alpha-2 Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 12 | 0.32 | Binding ≤ 10μM |
| ABL1-1-E | Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic | Eukaryotes | 91 | 0.28 | Binding ≤ 10μM |
| ABL2-1-E | Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.27 | Binding ≤ 10μM |
| ACK1-1-E | Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 17 | 0.31 | Binding ≤ 10μM |
| ACV1B-1-E | Activin Receptor Type-1B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 680 | 0.25 | Binding ≤ 10μM |
| ACVR1-1-E | Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 470 | 0.25 | Binding ≤ 10μM |
| AKT1-2-E | RAC-alpha Serine/threonine-protein Kinase (cluster #2 Of 3), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| AKT2-2-E | Serine/threonine-protein Kinase AKT2 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| AKT3-2-E | Serine/threonine-protein Kinase AKT3 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| ALK-1-E | ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 32 | 0.30 | Binding ≤ 10μM |
| ANKK1-1-E | Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 270 | 0.26 | Binding ≤ 10μM |
| AURKA-1-E | Serine/threonine-protein Kinase Aurora-A (cluster #1 Of 3), Eukaryotic | Eukaryotes | 22 | 0.31 | Binding ≤ 10μM |
| AURKB-1-E | Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 19 | 0.31 | Binding ≤ 10μM |
| AURKC-1-E | Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic | Eukaryotes | 23 | 0.31 | Binding ≤ 10μM |
| AVR2B-1-E | Activin Receptor Type-2B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4600 | 0.21 | Binding ≤ 10μM |
| BLK-1-E | Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 15 | 0.31 | Binding ≤ 10μM |
| BMP2K-1-E | BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| BMR1A-1-E | Bone Morphogenetic Protein Receptor Type-1A (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3700 | 0.22 | Binding ≤ 10μM |
| BMX-1-E | Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic | Eukaryotes | 410 | 0.26 | Binding ≤ 10μM |
| BRSK1-1-E | BR Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 26 | 0.30 | Binding ≤ 10μM |
| BRSK2-1-E | BR Serine/threonine-protein Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| BTK-1-E | Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 710 | 0.25 | Binding ≤ 10μM |
| CCNB1-1-E | G2/mitotic-specific Cyclin B1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| CCNB2-1-E | G2/mitotic-specific Cyclin B2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| CCNB3-1-E | G2/mitotic-specific Cyclin B3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| CCNE1-1-E | G1/S-specific Cyclin E1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 20 | 0.31 | Binding ≤ 10μM |
| CCNE2-1-E | G1/S-specific Cyclin E2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 20 | 0.31 | Binding ≤ 10μM |
| CDK1-1-E | Cyclin-dependent Kinase 1 (cluster #1 Of 4), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| CDK14-1-E | Serine/threonine-protein Kinase PFTAIRE-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.27 | Binding ≤ 10μM |
| CDK16-1-E | Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 25 | 0.30 | Binding ≤ 10μM |
| CDK17-1-E | Serine/threonine-protein Kinase PCTAIRE-2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 96 | 0.28 | Binding ≤ 10μM |
| CDK18-1-E | Serine/threonine-protein Kinase PCTAIRE-3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 270 | 0.26 | Binding ≤ 10μM |
| CDK19-1-E | Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.27 | Binding ≤ 10μM |
| CDK2-1-E | Cyclin-dependent Kinase 2 (cluster #1 Of 5), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| CDK3-1-E | Cyclin-dependent Kinase 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| CDK4-2-E | Cyclin-dependent Kinase 4 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 18 | 0.31 | Binding ≤ 10μM |
| CDK5-1-E | Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 89 | 0.28 | Binding ≤ 10μM |
| CDK6-1-E | Cyclin-dependent Kinase 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 116 | 0.28 | Binding ≤ 10μM |
| CDK7-1-E | Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 45 | 0.29 | Binding ≤ 10μM |
| CDK8-1-E | Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 510 | 0.25 | Binding ≤ 10μM |
| CDK9-1-E | Cyclin-dependent Kinase 9 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| CHK1-1-E | Serine/threonine-protein Kinase Chk1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 10 | 0.32 | Binding ≤ 10μM |
| CHK2-1-E | Serine/threonine-protein Kinase Chk2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| CLK1-2-E | Dual Specificty Protein Kinase CLK1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 32 | 0.30 | Binding ≤ 10μM |
| CLK2-1-E | Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| CLK3-1-E | Dual Specificity Protein Kinase CLK3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 910 | 0.24 | Binding ≤ 10μM |
| CLK4-1-E | Dual Specificity Protein Kinase CLK4 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 10 | 0.32 | Binding ≤ 10μM |
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 12 | 0.32 | Binding ≤ 10μM |
| CSK-1-E | Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 440 | 0.25 | Binding ≤ 10μM |
| CSK21-1-E | Casein Kinase II Alpha (cluster #1 Of 3), Eukaryotic | Eukaryotes | 7620 | 0.20 | Binding ≤ 10μM |
| CSK22-1-E | Casein Kinase II Alpha (prime) (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| CSK2B-1-E | Casein Kinase II Beta (cluster #1 Of 3), Eukaryotic | Eukaryotes | 7000 | 0.21 | Binding ≤ 10μM |
| CTRO-1-E | Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 340 | 0.26 | Binding ≤ 10μM |
| DAPK1-1-E | Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| DAPK2-1-E | Death-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| DAPK3-1-E | Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1500 | 0.23 | Binding ≤ 10μM |
| DCLK1-1-E | Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 110 | 0.28 | Binding ≤ 10μM |
| DCLK2-1-E | Serine/threonine-protein Kinase DCLK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 73 | 0.29 | Binding ≤ 10μM |
| DCLK3-1-E | Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 17 | 0.31 | Binding ≤ 10μM |
| DDR1-1-E | Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 19 | 0.31 | Binding ≤ 10μM |
| DDR2-1-E | Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 42 | 0.30 | Binding ≤ 10μM |
| DMPK-1-E | Myotonin-protein Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| DYR1B-1-E | Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 28 | 0.30 | Binding ≤ 10μM |
| E2AK2-1-E | Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 100 | 0.28 | Binding ≤ 10μM |
| E2AK2-1-E | Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 360 | 0.26 | Binding ≤ 10μM |
| E2AK4-1-E | Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 16 | 0.31 | Binding ≤ 10μM |
| EGFR-1-E | Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic | Eukaryotes | 96 | 0.28 | Binding ≤ 10μM |
| EPHA1-1-E | Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.26 | Binding ≤ 10μM |
| EPHA2-1-E | Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 870 | 0.24 | Binding ≤ 10μM |
| EPHA3-1-E | Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 55 | 0.29 | Binding ≤ 10μM |
| EPHA4-1-E | Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 710 | 0.25 | Binding ≤ 10μM |
| EPHA5-1-E | Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 95 | 0.28 | Binding ≤ 10μM |
| EPHA6-1-E | Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 290 | 0.26 | Binding ≤ 10μM |
| EPHA7-1-E | Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 690 | 0.25 | Binding ≤ 10μM |
| EPHA8-1-E | Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.26 | Binding ≤ 10μM |
| EPHB1-1-E | Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 590 | 0.25 | Binding ≤ 10μM |
| EPHB2-1-E | Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2100 | 0.23 | Binding ≤ 10μM |
| EPHB4-1-E | Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 233 | 0.27 | Binding ≤ 10μM |
| ERBB4-1-E | Receptor Protein-tyrosine Kinase ErbB-4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 282 | 0.26 | Binding ≤ 10μM |
| FAK1-1-E | Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 68 | 0.29 | Binding ≤ 10μM |
| FAK2-1-E | Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| FER-1-E | Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic | Eukaryotes | 30 | 0.30 | Binding ≤ 10μM |
| FES-1-E | Tyrosine-protein Kinase FES (cluster #1 Of 1), Eukaryotic | Eukaryotes | 23 | 0.31 | Binding ≤ 10μM |
| FGFR1-1-E | Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 90 | 0.28 | Binding ≤ 10μM |
| FGFR2-1-E | Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 420 | 0.26 | Binding ≤ 10μM |
| FGFR3-1-E | Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 88 | 0.28 | Binding ≤ 10μM |
| FGFR4-1-E | Fibroblast Growth Factor Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 420 | 0.26 | Binding ≤ 10μM |
| FGR-1-E | Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic | Eukaryotes | 30 | 0.30 | Binding ≤ 10μM |
| FLT3-1-E | Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| FRK-1-E | Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 45 | 0.29 | Binding ≤ 10μM |
| FYN-1-E | Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic | Eukaryotes | 83 | 0.28 | Binding ≤ 10μM |
| GAK-1-E | Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic | Eukaryotes | 68 | 0.29 | Binding ≤ 10μM |
| GSK3A-1-E | Glycogen Synthase Kinase-3 Alpha (cluster #1 Of 3), Eukaryotic | Eukaryotes | 140 | 0.27 | Binding ≤ 10μM |
| GSK3B-1-E | Glycogen Synthase Kinase-3 Beta (cluster #1 Of 7), Eukaryotic | Eukaryotes | 89 | 0.28 | Binding ≤ 10μM |
| HCK-1-E | Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 20 | 0.31 | Binding ≤ 10μM |
| HIPK1-1-E | Homeodomain-interacting Protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2639 | 0.22 | Binding ≤ 10μM |
| IGF1R-1-E | Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 35 | 0.30 | Binding ≤ 10μM |
| IKKA-2-E | Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit (cluster #2 Of 3), Eukaryotic | Eukaryotes | 39 | 0.30 | Binding ≤ 10μM |
| IKKB-1-E | Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 771 | 0.24 | Binding ≤ 10μM |
| IKKE-1-E | Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| INSR-1-E | Insulin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 200 | 0.27 | Binding ≤ 10μM |
| INSRR-1-E | Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic | Eukaryotes | 81 | 0.28 | Binding ≤ 10μM |
| IRAK3-1-E | Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 13 | 0.32 | Binding ≤ 10μM |
| IRAK4-1-E | Interleukin-1 Receptor-associated Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 34 | 0.30 | Binding ≤ 10μM |
| ITK-1-E | Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 19 | 0.31 | Binding ≤ 10μM |
| JAK2-1-E | Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| JAK3-1-E | Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| KAP2-1-E | CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 100 | 0.28 | Binding ≤ 10μM |
| KAPCA-1-E | CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 4), Eukaryotic | Eukaryotes | 27 | 0.30 | Binding ≤ 10μM |
| KAPCB-1-E | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit (cluster #1 Of 3), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| KAPCG-1-E | CAMP-dependent Protein Kinase, Gamma Catalytic Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 80 | 0.28 | Binding ≤ 10μM |
| KC1A-1-E | Casein Kinase I Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1400 | 0.23 | Binding ≤ 10μM |
| KC1AL-1-E | Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic | Eukaryotes | 250 | 0.26 | Binding ≤ 10μM |
| KC1D-1-E | Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1400 | 0.23 | Binding ≤ 10μM |
| KC1E-1-E | Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1400 | 0.23 | Binding ≤ 10μM |
| KC1G1-1-E | Casein Kinase I Gamma 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1400 | 0.23 | Binding ≤ 10μM |
| KC1G2-1-E | Casein Kinase I Gamma 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 780 | 0.24 | Binding ≤ 10μM |
| KCC1A-1-E | CaM Kinase I Alpha (cluster #1 Of 2), Eukaryotic | Eukaryotes | 40 | 0.30 | Binding ≤ 10μM |
| KCC1D-1-E | CaM Kinase I Delta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2 | 0.35 | Binding ≤ 10μM |
| KCC1G-1-E | CaM Kinase I Gamma (cluster #1 Of 2), Eukaryotic | Eukaryotes | 53 | 0.29 | Binding ≤ 10μM |
| KCC2A-1-E | CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| KCC2B-1-E | CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| KCC2D-1-E | CaM Kinase II Delta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| KCC2G-1-E | CaM Kinase II Gamma (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| KCC4-1-E | CaM Kinase IV (cluster #1 Of 1), Eukaryotic | Eukaryotes | 41 | 0.30 | Binding ≤ 10μM |
| KGP1-1-E | CGMP-dependent Protein Kinase 1 Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 32 | 0.30 | Binding ≤ 10μM |
| KGP2-1-E | CGMP-dependent Protein Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 16 | 0.31 | Binding ≤ 10μM |
| KIT-1-E | Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10 | 0.32 | Binding ≤ 10μM |
| KKCC1-1-E | CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| KKCC2-1-E | CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| KPB1-1-E | Phosphorylase Kinase Alpha M Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| KPB2-1-E | Phosphorylase Kinase Alpha L Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| KPBB-1-E | Phosphorylase Kinase Beta Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| KPCA-1-E | Protein Kinase C Alpha (cluster #1 Of 6), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KPCB-1-E | Protein Kinase C Beta (cluster #1 Of 4), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| KPCD-1-E | Protein Kinase C Delta (cluster #1 Of 4), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KPCD1-1-E | Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KPCD2-1-E | Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 72 | 0.29 | Binding ≤ 10μM |
| KPCD3-1-E | Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KPCE-1-E | Protein Kinase C Epsilon (cluster #1 Of 5), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KPCG-1-E | Protein Kinase C Gamma (cluster #1 Of 4), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| KPCI-1-E | Protein Kinase C Iota (cluster #1 Of 3), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KPCL-2-E | Protein Kinase C Eta (cluster #2 Of 4), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| KPCT-1-E | Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| KPCZ-1-E | Protein Kinase C Zeta (cluster #1 Of 5), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| KS6A1-1-E | Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| KS6A2-1-E | Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| KS6A3-1-E | Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 69 | 0.29 | Binding ≤ 10μM |
| KS6A4-1-E | Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| KS6A5-1-E | Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 890 | 0.24 | Binding ≤ 10μM |
| KS6A6-1-E | Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| KS6B1-1-E | Ribosomal Protein S6 Kinase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| KS6B2-1-E | Ribosomal Protein S6 Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| KSYK-1-E | Tyrosine-protein Kinase SYK (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| LATS1-1-E | Serine/threonine-protein Kinase LATS1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 42 | 0.30 | Binding ≤ 10μM |
| LATS2-1-E | Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 17 | 0.31 | Binding ≤ 10μM |
| LCK-1-E | Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| LIMK1-1-E | LIM Domain Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 690 | 0.25 | Binding ≤ 10μM |
| LIMK2-1-E | LIM Domain Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9200 | 0.20 | Binding ≤ 10μM |
| LTK-1-E | Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 37 | 0.30 | Binding ≤ 10μM |
| LYN-1-E | Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic | Eukaryotes | 40 | 0.30 | Binding ≤ 10μM |
| M3K10-1-E | Mitogen-activated Protein Kinase Kinase Kinase 10 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 52 | 0.29 | Binding ≤ 10μM |
| M3K11-1-E | Mitogen-activated Protein Kinase Kinase Kinase 11 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 20 | 0.31 | Binding ≤ 10μM |
| M3K14-1-E | Mitogen-activated Protein Kinase Kinase Kinase 14 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2300 | 0.23 | Binding ≤ 10μM |
| M3K4-1-E | Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2200 | 0.23 | Binding ≤ 10μM |
| M3K5-1-E | Mitogen-activated Protein Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 37 | 0.30 | Binding ≤ 10μM |
| M3K7-1-E | Mitogen-activated Protein Kinase Kinase Kinase 7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 35 | 0.30 | Binding ≤ 10μM |
| M3K9-1-E | Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10 | 0.32 | Binding ≤ 10μM |
| M4K1-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| M4K3-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| M4K4-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 24 | 0.30 | Binding ≤ 10μM |
| M4K5-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 26 | 0.30 | Binding ≤ 10μM |
| MAPK2-1-E | MAP Kinase-activated Protein Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 880 | 0.24 | Binding ≤ 10μM |
| MARK1-1-E | Serine/threonine-protein Kinase MARK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| MARK2-1-E | MAP/microtubule Affinity-regulating Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| MARK3-1-E | Serine/threonine-protein Kinase C-TAK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| MARK4-1-E | MAP/microtubule Affinity-regulating Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| MELK-1-E | Maternal Embryonic Leucine Zipper Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 33 | 0.30 | Binding ≤ 10μM |
| MERTK-1-E | Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| MET-1-E | Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.27 | Binding ≤ 10μM |
| MINK1-1-E | Misshapen-like Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| MK01-1-E | Mitogen-activated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7300 | 0.21 | Binding ≤ 10μM |
| MK03-1-E | MAP Kinase ERK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8400 | 0.20 | Binding ≤ 10μM |
| MK07-1-E | Mitogen-activated Protein Kinase 7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1600 | 0.23 | Binding ≤ 10μM |
| MK08-1-E | Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic | Eukaryotes | 520 | 0.25 | Binding ≤ 10μM |
| MK09-1-E | C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1100 | 0.24 | Binding ≤ 10μM |
| MK10-1-E | C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 340 | 0.26 | Binding ≤ 10μM |
| MK11-1-E | MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.24 | Binding ≤ 10μM |
| MK12-1-E | MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic | Eukaryotes | 92 | 0.28 | Binding ≤ 10μM |
| MK13-1-E | MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.24 | Binding ≤ 10μM |
| MK14-1-E | MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.24 | Binding ≤ 10μM |
| MK15-1-E | Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 35 | 0.30 | Binding ≤ 10μM |
| MKNK1-1-E | MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 170 | 0.27 | Binding ≤ 10μM |
| MKNK2-1-E | MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 22 | 0.31 | Binding ≤ 10μM |
| MP2K1-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic | Eukaryotes | 670 | 0.25 | Binding ≤ 10μM |
| MP2K2-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 28 | 0.30 | Binding ≤ 10μM |
| MP2K3-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.33 | Binding ≤ 10μM |
| MP2K4-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 70 | 0.29 | Binding ≤ 10μM |
| MP2K6-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| MRCKA-1-E | Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic | Eukaryotes | 57 | 0.29 | Binding ≤ 10μM |
| MRCKB-1-E | Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 42 | 0.30 | Binding ≤ 10μM |
| MRCKG-1-E | Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic | Eukaryotes | 37 | 0.30 | Binding ≤ 10μM |
| MST4-1-E | Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 140 | 0.27 | Binding ≤ 10μM |
| MUSK-1-E | Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 86 | 0.28 | Binding ≤ 10μM |
| MYLK-1-E | Myosin Light Chain Kinase, Smooth Muscle (cluster #1 Of 1), Eukaryotic | Eukaryotes | 40 | 0.30 | Binding ≤ 10μM |
| MYLK2-1-E | Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 61 | 0.29 | Binding ≤ 10μM |
| MYLK4-1-E | Myosin Light Chain Kinase Family Member 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 470 | 0.25 | Binding ≤ 10μM |
| MYO3A-1-E | Myosin IIIA (cluster #1 Of 1), Eukaryotic | Eukaryotes | 500 | 0.25 | Binding ≤ 10μM |
| MYO3B-1-E | Myosin-IIIB (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.26 | Binding ≤ 10μM |
| NEK1-1-E | Serine/threonine-protein Kinase Nek1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 860 | 0.24 | Binding ≤ 10μM |
| NEK2-1-E | Serine/threonine-protein Kinase NEK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 750 | 0.24 | Binding ≤ 10μM |
| NEK5-1-E | Serine/threonine-protein Kinase Nek5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 810 | 0.24 | Binding ≤ 10μM |
| NEK7-1-E | Serine/threonine-protein Kinase NEK7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4500 | 0.21 | Binding ≤ 10μM |
| NEK9-1-E | Serine/threonine-protein Kinase NEK9 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6700 | 0.21 | Binding ≤ 10μM |
| NLK-1-E | Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 220 | 0.27 | Binding ≤ 10μM |
| NTRK1-1-E | Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| NTRK2-1-E | Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| NTRK3-1-E | NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 17 | 0.31 | Binding ≤ 10μM |
| NUAK1-1-E | NUAK Family SNF1-like Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.34 | Binding ≤ 10μM |
| NUAK2-1-E | NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| P90584-2-E | Protein Kinase Pfmrk (cluster #2 Of 2), Eukaryotic | Eukaryotes | 4000 | 0.22 | Binding ≤ 10μM |
| PAK1-1-E | Serine/threonine-protein Kinase PAK 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.35 | Binding ≤ 10μM |
| PAK2-1-E | Serine/threonine-protein Kinase PAK 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| PAK3-1-E | Serine/threonine-protein Kinase PAK 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| PAK4-1-E | Serine/threonine-protein Kinase PAK 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| PAK6-1-E | Serine/threonine-protein Kinase PAK6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| PAK7-1-E | Serine/threonine-protein Kinase PAK7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| PDPK1-1-E | 3-phosphoinositide Dependent Protein Kinase-1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2 | 0.35 | Binding ≤ 10μM |
| PGFRA-1-E | Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2 | 0.35 | Binding ≤ 10μM |
| PGFRB-1-E | Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| PHKG1-1-E | Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| PHKG2-1-E | Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| PI42B-1-E | Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 77 | 0.28 | Binding ≤ 10μM |
| PI51A-1-E | Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 43 | 0.29 | Binding ≤ 10μM |
| PIM1-1-E | Serine/threonine-protein Kinase PIM1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8 | 0.32 | Binding ≤ 10μM |
| PIM2-1-E | Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| PIM3-1-E | Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| PKN1-1-E | Protein Kinase N1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| PKN2-1-E | Protein Kinase N2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| PLK1-1-E | Serine/threonine-protein Kinase PLK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.27 | Binding ≤ 10μM |
| PLK2-1-E | Serine/threonine-protein Kinase PLK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 197 | 0.27 | Binding ≤ 10μM |
| PLK3-1-E | Serine/threonine-protein Kinase PLK3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 910 | 0.24 | Binding ≤ 10μM |
| PLK4-1-E | Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| PRKX-1-E | Serine/threonine-protein Kinase PRKX (cluster #1 Of 1), Eukaryotic | Eukaryotes | 13 | 0.32 | Binding ≤ 10μM |
| PTK6-1-E | Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2300 | 0.23 | Binding ≤ 10μM |
| Q95J97-1-E | CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 80 | 0.28 | Binding ≤ 10μM |
| RAF1-1-E | Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| RET-1-E | Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic | Eukaryotes | 28 | 0.30 | Binding ≤ 10μM |
| RIOK1-1-E | Serine/threonine-protein Kinase RIO1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 130 | 0.28 | Binding ≤ 10μM |
| RIOK3-1-E | Serine/threonine-protein Kinase RIO3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 76 | 0.28 | Binding ≤ 10μM |
| RIPK2-1-E | Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5200 | 0.21 | Binding ≤ 10μM |
| ROCK1-1-E | Rho-associated Protein Kinase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| ROS1-1-E | Proto-oncogene Tyrosine-protein Kinase ROS (cluster #1 Of 1), Eukaryotic | Eukaryotes | 30 | 0.30 | Binding ≤ 10μM |
| SIK1-1-E | Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.35 | Binding ≤ 10μM |
| SIK2-1-E | Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| SLK-1-E | Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| SRC-1-E | Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic | Eukaryotes | 86 | 0.28 | Binding ≤ 10μM |
| SRMS-1-E | Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic | Eukaryotes | 740 | 0.25 | Binding ≤ 10μM |
| SRPK1-1-E | Serine/threonine-protein Kinase SRPK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| SRPK2-1-E | Serine/threonine-protein Kinase SRPK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 67 | 0.29 | Binding ≤ 10μM |
| ST17A-1-E | Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic | Eukaryotes | 23 | 0.31 | Binding ≤ 10μM |
| ST17B-1-E | Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 26 | 0.30 | Binding ≤ 10μM |
| ST32B-1-E | Serine/threonine-protein Kinase 32B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 98 | 0.28 | Binding ≤ 10μM |
| ST32C-1-E | Serine/threonine-protein Kinase 32C (cluster #1 Of 1), Eukaryotic | Eukaryotes | 310 | 0.26 | Binding ≤ 10μM |
| ST38L-1-E | Serine/threonine-protein Kinase 38-like (cluster #1 Of 2), Eukaryotic | Eukaryotes | 77 | 0.28 | Binding ≤ 10μM |
| STK10-1-E | Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| STK11-1-E | Serine/threonine-protein Kinase 11 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 61 | 0.29 | Binding ≤ 10μM |
| STK16-1-E | Serine/threonine-protein Kinase 16 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 270 | 0.26 | Binding ≤ 10μM |
| STK24-1-E | Serine/threonine-protein Kinase 24 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 120 | 0.28 | Binding ≤ 10μM |
| STK25-1-E | Serine/threonine-protein Kinase 25 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 110 | 0.28 | Binding ≤ 10μM |
| STK3-1-E | Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| STK33-1-E | Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.35 | Binding ≤ 10μM |
| STK36-1-E | Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6700 | 0.21 | Binding ≤ 10μM |
| STK4-1-E | Serine/threonine-protein Kinase MST1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| SYK-1-E | Lysyl-tRNA Synthetase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9 | 0.32 | Binding ≤ 10μM |
| TAB1-1-E | Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 35 | 0.30 | Binding ≤ 10μM |
| TBA1A-1-E | Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic | Eukaryotes | 770 | 0.24 | Binding ≤ 10μM |
| TEC-1-E | Tyrosine-protein Kinase TEC (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1300 | 0.24 | Binding ≤ 10μM |
| TESK1-1-E | Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 320 | 0.26 | Binding ≤ 10μM |
| TGFR1-1-E | TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 0.23 | Binding ≤ 10μM |
| TIE1-1-E | Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 65 | 0.29 | Binding ≤ 10μM |
| TIE2-1-E | Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 52 | 0.29 | Binding ≤ 10μM |
| TLK1-1-E | Serine/threonine-protein Kinase Tousled-like 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 27 | 0.30 | Binding ≤ 10μM |
| TLK2-1-E | Serine/threonine-protein Kinase Tousled-like 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 16 | 0.31 | Binding ≤ 10μM |
| TNI3K-1-E | Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.24 | Binding ≤ 10μM |
| TNIK-1-E | TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6 | 0.33 | Binding ≤ 10μM |
| TNK1-1-E | Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| TSSK1-1-E | Testis-specific Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 24 | 0.30 | Binding ≤ 10μM |
| TTK-1-E | Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic | Eukaryotes | 61 | 0.29 | Binding ≤ 10μM |
| TXK-1-E | Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 230 | 0.27 | Binding ≤ 10μM |
| TYK2-1-E | Tyrosine-protein Kinase TYK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 56 | 0.29 | Binding ≤ 10μM |
| TYRO3-1-E | Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 49 | 0.29 | Binding ≤ 10μM |
| UFO-1-E | Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7 | 0.33 | Binding ≤ 10μM |
| ULK3-1-E | Serine/threonine-protein Kinase ULK3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3 | 0.34 | Binding ≤ 10μM |
| VGFR1-1-E | Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 14 | 0.31 | Binding ≤ 10μM |
| VGFR2-1-E | Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 88 | 0.28 | Binding ≤ 10μM |
| VGFR3-1-E | Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 14 | 0.31 | Binding ≤ 10μM |
| WEE1-1-E | Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1600 | 0.23 | Binding ≤ 10μM |
| YES-1-E | Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic | Eukaryotes | 52 | 0.29 | Binding ≤ 10μM |
| ZAP70-1-E | Tyrosine-protein Kinase ZAP-70 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 53 | 0.29 | Binding ≤ 10μM |
| AKT1-1-E | Serine/threonine-protein Kinase AKT (cluster #1 Of 1), Eukaryotic | Eukaryotes | 460 | 0.25 | Functional ≤ 10μM |
| KPCB-1-E | Protein Kinase C Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 77 | 0.28 | Functional ≤ 10μM |
| Z104294-1-O | Cyclin-dependent Kinase 5/CDK5 Activator 1 (cluster #1 Of 2), Other | Other | 10 | 0.32 | Binding ≤ 10μM |
| Z104295-1-O | Cyclin-dependent Kinase 4/cyclin D1 (cluster #1 Of 2), Other | Other | 59 | 0.29 | Binding ≤ 10μM |
| Z100081-2-O | PBMC (Peripheral Blood Mononuclear Cells) (cluster #2 Of 4), Other | Other | 16 | 0.31 | Functional ≤ 10μM |
| Z100201-1-O | Splenocytes (Spleen Cells) (cluster #1 Of 1), Other | Other | 400 | 0.26 | Functional ≤ 10μM |
| Z50425-3-O | Plasmodium Falciparum (cluster #3 Of 22), Other | Other | 190 | 0.27 | Functional ≤ 10μM |
| Z50512-1-O | Cavia Porcellus (cluster #1 Of 7), Other | Other | 7500 | 0.20 | Functional ≤ 10μM |
| Z80120-1-O | DLD-1 (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other | Other | 9 | 0.32 | Functional ≤ 10μM |
| Z80166-1-O | HT-29 (Colon Adenocarcinoma Cells) (cluster #1 Of 12), Other | Other | 3 | 0.34 | Functional ≤ 10μM |
| Z80211-1-O | LoVo (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other | Other | 1 | 0.36 | Functional ≤ 10μM |
| Z80224-1-O | MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other | Other | 50 | 0.29 | Functional ≤ 10μM |
| Z80800-1-O | MIA PaCa-2 (Pancreatic Carcinoma Cells) (cluster #1 Of 2), Other | Other | 370 | 0.26 | Functional ≤ 10μM |
| Z80928-1-O | HCT-116 (Colon Carcinoma Cells) (cluster #1 Of 9), Other | Other | 6 | 0.33 | Functional ≤ 10μM |
| Z80936-1-O | HEK293 (Embryonic Kidney Fibroblasts) (cluster #1 Of 4), Other | Other | 77 | 0.28 | Functional ≤ 10μM |
| Z81057-1-O | HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other | Other | 4 | 0.34 | Functional ≤ 10μM |
| Z81072-1-O | Jurkat (Acute Leukemic T-cells) (cluster #1 Of 10), Other | Other | 71 | 0.29 | Functional ≤ 10μM |
| Z81247-1-O | HeLa (Cervical Adenocarcinoma Cells) (cluster #1 Of 9), Other | Other | 0 | 0.00 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PDPK1_HUMAN | O15530 | 3-phosphoinositide Dependent Protein Kinase-1, Human | 1.7 | 0.35 | Binding ≤ 1μM |
| ACVR1_HUMAN | Q04771 | Activin Receptor Type-1, Human | 470 | 0.25 | Binding ≤ 1μM |
| ACV1B_HUMAN | P36896 | Activin Receptor Type-1B, Human | 680 | 0.25 | Binding ≤ 1μM |
| AAK1_HUMAN | Q2M2I8 | Adaptor-associated Kinase, Human | 1.2 | 0.36 | Binding ≤ 1μM |
| ALK_HUMAN | Q9UM73 | ALK Tyrosine Kinase Receptor, Human | 32 | 0.30 | Binding ≤ 1μM |
| AAPK1_HUMAN | Q13131 | AMP-activated Protein Kinase, Alpha-1 Subunit, Human | 3.7 | 0.34 | Binding ≤ 1μM |
| AAPK2_HUMAN | P54646 | AMP-activated Protein Kinase, Alpha-2 Subunit, Human | 12 | 0.32 | Binding ≤ 1μM |
| ANKK1_HUMAN | Q8NFD2 | Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human | 270 | 0.26 | Binding ≤ 1μM |
| BMP2K_HUMAN | Q9NSY1 | BMP-2-inducible Protein Kinase, Human | 3.7 | 0.34 | Binding ≤ 1μM |
| BRSK1_HUMAN | Q8TDC3 | BR Serine/threonine-protein Kinase 1, Human | 26 | 0.30 | Binding ≤ 1μM |
| BRSK2_HUMAN | Q8IWQ3 | BR Serine/threonine-protein Kinase 2, Human | 3.5 | 0.34 | Binding ≤ 1μM |
| MK08_HUMAN | P45983 | C-Jun N-terminal Kinase 1, Human | 220 | 0.27 | Binding ≤ 1μM |
| MK10_HUMAN | P53779 | C-Jun N-terminal Kinase 3, Human | 110 | 0.28 | Binding ≤ 1μM |
| KCC1A_HUMAN | Q14012 | CaM Kinase I Alpha, Human | 27 | 0.30 | Binding ≤ 1μM |
| KCC1D_HUMAN | Q8IU85 | CaM Kinase I Delta, Human | 1.1 | 0.36 | Binding ≤ 1μM |
| KCC1G_HUMAN | Q96NX5 | CaM Kinase I Gamma, Human | 23 | 0.31 | Binding ≤ 1μM |
| KCC2A_MOUSE | P11798 | CaM Kinase II Alpha, Mouse | 6 | 0.33 | Binding ≤ 1μM |
| KCC2A_RAT | P11275 | CaM Kinase II Alpha, Rat | 2 | 0.35 | Binding ≤ 1μM |
| KCC2A_HUMAN | Q9UQM7 | CaM Kinase II Alpha, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KCC2B_HUMAN | Q13554 | CaM Kinase II Beta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KCC2B_MOUSE | P28652 | CaM Kinase II Beta, Mouse | 6 | 0.33 | Binding ≤ 1μM |
| KCC2D_HUMAN | Q13557 | CaM Kinase II Delta, Human | 0.32 | 0.38 | Binding ≤ 1μM |
| KCC2G_HUMAN | Q13555 | CaM Kinase II Gamma, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| KCC2G_MOUSE | Q923T9 | CaM Kinase II Gamma, Mouse | 6 | 0.33 | Binding ≤ 1μM |
| KCC4_HUMAN | Q16566 | CaM Kinase IV, Human | 4 | 0.34 | Binding ≤ 1μM |
| KKCC1_HUMAN | Q8N5S9 | CaM-kinase Kinase Alpha, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KKCC2_HUMAN | Q96RR4 | CaM-kinase Kinase Beta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| Q95J97_RABIT | Q95J97 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit | 80 | 0.28 | Binding ≤ 1μM |
| KAPCA_HUMAN | P17612 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human | 0.9 | 0.36 | Binding ≤ 1μM |
| KAPCA_BOVIN | P00517 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin | 100 | 0.28 | Binding ≤ 1μM |
| KAPCA_RAT | P27791 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat | 120 | 0.28 | Binding ≤ 1μM |
| KAPCA_MOUSE | P05132 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse | 4 | 0.34 | Binding ≤ 1μM |
| KAPCB_BOVIN | P05131 | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin | 100 | 0.28 | Binding ≤ 1μM |
| KAPCB_HUMAN | P22694 | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human | 0.9 | 0.36 | Binding ≤ 1μM |
| KAPCB_MOUSE | P68181 | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse | 4 | 0.34 | Binding ≤ 1μM |
| KAP2_BOVIN | P00515 | CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin | 100 | 0.28 | Binding ≤ 1μM |
| KAPCG_HUMAN | P22612 | CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human | 0.9 | 0.36 | Binding ≤ 1μM |
| KC1E_HUMAN | P49674 | Casein Kinase I Epsilon, Human | 690 | 0.25 | Binding ≤ 1μM |
| KC1G2_HUMAN | P78368 | Casein Kinase I Gamma 2, Human | 780 | 0.24 | Binding ≤ 1μM |
| KC1AL_HUMAN | Q8N752 | Casein Kinase I Isoform Alpha-like, Human | 250 | 0.26 | Binding ≤ 1μM |
| CSK21_HUMAN | P68400 | Casein Kinase II Alpha, Human | 36 | 0.30 | Binding ≤ 1μM |
| CSK22_HUMAN | P19784 | Casein Kinase II Alpha (prime), Human | 6.5 | 0.33 | Binding ≤ 1μM |
| CDK19_HUMAN | Q9BWU1 | Cell Division Cycle 2-like Protein Kinase 6, Human | 190 | 0.27 | Binding ≤ 1μM |
| CDK8_HUMAN | P49336 | Cell Division Protein Kinase 8, Human | 510 | 0.25 | Binding ≤ 1μM |
| KGP1_BOVIN | P00516 | CGMP-dependent Protein Kinase 1 Alpha, Bovin | 18 | 0.31 | Binding ≤ 1μM |
| KGP1_HUMAN | Q13976 | CGMP-dependent Protein Kinase 1 Beta, Human | 32 | 0.30 | Binding ≤ 1μM |
| KGP2_HUMAN | Q13237 | CGMP-dependent Protein Kinase 2, Human | 16 | 0.31 | Binding ≤ 1μM |
| CTRO_HUMAN | O14578 | Citron Rho-interacting Kinase, Human | 340 | 0.26 | Binding ≤ 1μM |
| CDK1_HUMAN | P06493 | Cyclin-dependent Kinase 1, Human | 0.4 | 0.38 | Binding ≤ 1μM |
| CDK1_MOUSE | P11440 | Cyclin-dependent Kinase 1, Mouse | 8 | 0.32 | Binding ≤ 1μM |
| CDK2_HUMAN | P24941 | Cyclin-dependent Kinase 2, Human | 0.36 | 0.38 | Binding ≤ 1μM |
| CDK3_HUMAN | Q00526 | Cyclin-dependent Kinase 3, Human | 30 | 0.30 | Binding ≤ 1μM |
| CDK4_HUMAN | P11802 | Cyclin-dependent Kinase 4, Human | 18.3 | 0.31 | Binding ≤ 1μM |
| Z104295 | Z104295 | Cyclin-dependent Kinase 4/cyclin D1 | 59 | 0.29 | Binding ≤ 1μM |
| CDK5_HUMAN | Q00535 | Cyclin-dependent Kinase 5, Human | 3.8 | 0.34 | Binding ≤ 1μM |
| Z104294 | Z104294 | Cyclin-dependent Kinase 5/CDK5 Activator 1 | 10 | 0.32 | Binding ≤ 1μM |
| CDK6_HUMAN | Q00534 | Cyclin-dependent Kinase 6, Human | 116 | 0.28 | Binding ≤ 1μM |
| CDK7_HUMAN | P50613 | Cyclin-dependent Kinase 7, Human | 45 | 0.29 | Binding ≤ 1μM |
| CDK9_HUMAN | P50750 | Cyclin-dependent Kinase 9, Human | 100 | 0.28 | Binding ≤ 1μM |
| DAPK1_HUMAN | P53355 | Death-associated Protein Kinase 1, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| DAPK2_HUMAN | Q9UIK4 | Death-associated Protein Kinase 2, Human | 1.6 | 0.35 | Binding ≤ 1μM |
| DAPK3_HUMAN | O43293 | Death-associated Protein Kinase 3, Human | 1 | 0.36 | Binding ≤ 1μM |
| DDR2_HUMAN | Q16832 | Discoidin Domain-containing Receptor 2, Human | 42 | 0.30 | Binding ≤ 1μM |
| MP2K1_HUMAN | Q02750 | Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human | 1000 | 0.24 | Binding ≤ 1μM |
| MP2K2_HUMAN | P36507 | Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human | 28 | 0.30 | Binding ≤ 1μM |
| MP2K3_HUMAN | P46734 | Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human | 5 | 0.33 | Binding ≤ 1μM |
| MP2K4_HUMAN | P45985 | Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human | 1 | 0.36 | Binding ≤ 1μM |
| MP2K6_HUMAN | P52564 | Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human | 1 | 0.36 | Binding ≤ 1μM |
| CLK2_HUMAN | P49760 | Dual Specificity Protein Kinase CLK2, Human | 12 | 0.32 | Binding ≤ 1μM |
| CLK3_HUMAN | P49761 | Dual Specificity Protein Kinase CLK3, Human | 910 | 0.24 | Binding ≤ 1μM |
| CLK4_HUMAN | Q9HAZ1 | Dual Specificity Protein Kinase CLK4, Human | 15 | 0.31 | Binding ≤ 1μM |
| TTK_HUMAN | P33981 | Dual Specificity Protein Kinase TTK, Human | 100 | 0.28 | Binding ≤ 1μM |
| TESK1_HUMAN | Q15569 | Dual Specificity Testis-specific Protein Kinase 1, Human | 320 | 0.26 | Binding ≤ 1μM |
| DYR1B_HUMAN | Q9Y463 | Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human | 28 | 0.30 | Binding ≤ 1μM |
| CLK1_HUMAN | P49759 | Dual Specificty Protein Kinase CLK1, Human | 27 | 0.30 | Binding ≤ 1μM |
| EPHA1_HUMAN | P21709 | Ephrin Type-A Receptor 1, Human | 300 | 0.26 | Binding ≤ 1μM |
| EPHA2_HUMAN | P29317 | Ephrin Type-A Receptor 2, Human | 870 | 0.24 | Binding ≤ 1μM |
| EPHA3_HUMAN | P29320 | Ephrin Type-A Receptor 3, Human | 27 | 0.30 | Binding ≤ 1μM |
| EPHA4_HUMAN | P54764 | Ephrin Type-A Receptor 4, Human | 290 | 0.26 | Binding ≤ 1μM |
| EPHA5_HUMAN | P54756 | Ephrin Type-A Receptor 5, Human | 150 | 0.27 | Binding ≤ 1μM |
| EPHA6_HUMAN | Q9UF33 | Ephrin Type-A Receptor 6, Human | 240 | 0.26 | Binding ≤ 1μM |
| EPHA7_HUMAN | Q15375 | Ephrin Type-A Receptor 7, Human | 630 | 0.25 | Binding ≤ 1μM |
| EPHA8_HUMAN | P29322 | Ephrin Type-A Receptor 8, Human | 190 | 0.27 | Binding ≤ 1μM |
| EPHB1_HUMAN | P54762 | Ephrin Type-B Receptor 1, Human | 240 | 0.26 | Binding ≤ 1μM |
| EPHB4_HUMAN | P54760 | Ephrin Type-B Receptor 4, Human | 233 | 0.27 | Binding ≤ 1μM |
| EGFR_HUMAN | P00533 | Epidermal Growth Factor Receptor ErbB1, Human | 100 | 0.28 | Binding ≤ 1μM |
| DDR1_HUMAN | Q08345 | Epithelial Discoidin Domain-containing Receptor 1, Human | 19 | 0.31 | Binding ≤ 1μM |
| E2AK4_HUMAN | Q9P2K8 | Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human | 16 | 0.31 | Binding ≤ 1μM |
| FGFR1_HUMAN | P11362 | Fibroblast Growth Factor Receptor 1, Human | 420 | 0.26 | Binding ≤ 1μM |
| FGFR2_HUMAN | P21802 | Fibroblast Growth Factor Receptor 2, Human | 100 | 0.28 | Binding ≤ 1μM |
| FGFR3_HUMAN | P22607 | Fibroblast Growth Factor Receptor 3, Human | 110 | 0.28 | Binding ≤ 1μM |
| FGFR4_HUMAN | P22455 | Fibroblast Growth Factor Receptor 4, Human | 250 | 0.26 | Binding ≤ 1μM |
| FAK1_HUMAN | Q05397 | Focal Adhesion Kinase 1, Human | 64 | 0.29 | Binding ≤ 1μM |
| CCNE1_HUMAN | P24864 | G1/S-specific Cyclin E1, Human | 12 | 0.32 | Binding ≤ 1μM |
| CCNE2_HUMAN | O96020 | G1/S-specific Cyclin E2, Human | 12 | 0.32 | Binding ≤ 1μM |
| CCNB1_HUMAN | P14635 | G2/mitotic-specific Cyclin B1, Human | 12 | 0.32 | Binding ≤ 1μM |
| CCNB2_HUMAN | O95067 | G2/mitotic-specific Cyclin B2, Human | 12 | 0.32 | Binding ≤ 1μM |
| CCNB3_HUMAN | Q8WWL7 | G2/mitotic-specific Cyclin B3, Human | 12 | 0.32 | Binding ≤ 1μM |
| GSK3A_HUMAN | P49840 | Glycogen Synthase Kinase-3 Alpha, Human | 12 | 0.32 | Binding ≤ 1μM |
| GSK3B_HUMAN | P49841 | Glycogen Synthase Kinase-3 Beta, Human | 12 | 0.32 | Binding ≤ 1μM |
| MET_HUMAN | P08581 | Hepatocyte Growth Factor Receptor, Human | 103 | 0.28 | Binding ≤ 1μM |
| IKKA_HUMAN | O15111 | Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human | 233 | 0.27 | Binding ≤ 1μM |
| IKKB_HUMAN | O14920 | Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human | 250 | 0.26 | Binding ≤ 1μM |
| IKKE_HUMAN | Q14164 | Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human | 5.1 | 0.33 | Binding ≤ 1μM |
| INSR_HUMAN | P06213 | Insulin Receptor, Human | 110 | 0.28 | Binding ≤ 1μM |
| INSR_MOUSE | P15208 | Insulin Receptor, Mouse | 200 | 0.27 | Binding ≤ 1μM |
| INSRR_HUMAN | P14616 | Insulin Receptor-related Protein, Human | 81 | 0.28 | Binding ≤ 1μM |
| IGF1R_HUMAN | P08069 | Insulin-like Growth Factor I Receptor, Human | 200 | 0.27 | Binding ≤ 1μM |
| E2AK2_HUMAN | P19525 | Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human | 360 | 0.26 | Binding ≤ 1μM |
| IRAK3_HUMAN | Q9Y616 | Interleukin-1 Receptor-associated Kinase 3, Human | 13 | 0.32 | Binding ≤ 1μM |
| IRAK4_HUMAN | Q9NWZ3 | Interleukin-1 Receptor-associated Kinase 4, Human | 34 | 0.30 | Binding ≤ 1μM |
| LTK_HUMAN | P29376 | Leukocyte Tyrosine Kinase Receptor, Human | 37 | 0.30 | Binding ≤ 1μM |
| LIMK1_HUMAN | P53667 | LIM Domain Kinase 1, Human | 480 | 0.25 | Binding ≤ 1μM |
| SYK_HUMAN | Q15046 | Lysyl-tRNA Synthetase, Human | 9 | 0.32 | Binding ≤ 1μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 12 | 0.32 | Binding ≤ 1μM |
| MK01_HUMAN | P28482 | MAP Kinase ERK2, Human | 1 | 0.36 | Binding ≤ 1μM |
| MK14_HUMAN | Q16539 | MAP Kinase P38 Alpha, Human | 1000 | 0.24 | Binding ≤ 1μM |
| MK11_HUMAN | Q15759 | MAP Kinase P38 Beta, Human | 1000 | 0.24 | Binding ≤ 1μM |
| MK13_HUMAN | O15264 | MAP Kinase P38 Delta, Human | 1000 | 0.24 | Binding ≤ 1μM |
| MK12_HUMAN | P53778 | MAP Kinase P38 Gamma, Human | 1000 | 0.24 | Binding ≤ 1μM |
| MKNK2_HUMAN | Q9HBH9 | MAP Kinase Signal-integrating Kinase 2, Human | 17 | 0.31 | Binding ≤ 1μM |
| MAPK2_HUMAN | P49137 | MAP Kinase-activated Protein Kinase 2, Human | 110 | 0.28 | Binding ≤ 1μM |
| MKNK1_HUMAN | Q9BUB5 | MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human | 170 | 0.27 | Binding ≤ 1μM |
| MARK2_HUMAN | Q7KZI7 | MAP/microtubule Affinity-regulating Kinase 2, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| MARK4_HUMAN | Q96L34 | MAP/microtubule Affinity-regulating Kinase 4, Human | 5.4 | 0.33 | Binding ≤ 1μM |
| MELK_HUMAN | Q14680 | Maternal Embryonic Leucine Zipper Kinase, Human | 33 | 0.30 | Binding ≤ 1μM |
| MINK1_HUMAN | Q8N4C8 | Misshapen-like Kinase 1, Human | 0.49 | 0.37 | Binding ≤ 1μM |
| MK15_HUMAN | Q8TD08 | Mitogen-activated Protein Kinase 15, Human | 35 | 0.30 | Binding ≤ 1μM |
| M3K10_HUMAN | Q02779 | Mitogen-activated Protein Kinase Kinase Kinase 10, Human | 52 | 0.29 | Binding ≤ 1μM |
| M3K11_HUMAN | Q16584 | Mitogen-activated Protein Kinase Kinase Kinase 11, Human | 20 | 0.31 | Binding ≤ 1μM |
| M3K5_HUMAN | Q99683 | Mitogen-activated Protein Kinase Kinase Kinase 5, Human | 1000 | 0.24 | Binding ≤ 1μM |
| M3K7_HUMAN | O43318 | Mitogen-activated Protein Kinase Kinase Kinase 7, Human | 35 | 0.30 | Binding ≤ 1μM |
| TAB1_HUMAN | Q15750 | Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1, Human | 35 | 0.30 | Binding ≤ 1μM |
| M3K9_HUMAN | P80192 | Mitogen-activated Protein Kinase Kinase Kinase 9, Human | 10 | 0.32 | Binding ≤ 1μM |
| M4K1_HUMAN | Q92918 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human | 4.3 | 0.33 | Binding ≤ 1μM |
| M4K3_HUMAN | Q8IVH8 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human | 8.2 | 0.32 | Binding ≤ 1μM |
| M4K4_HUMAN | O95819 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human | 24 | 0.30 | Binding ≤ 1μM |
| M4K5_HUMAN | Q9Y4K4 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human | 18 | 0.31 | Binding ≤ 1μM |
| MUSK_HUMAN | O15146 | Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human | 86 | 0.28 | Binding ≤ 1μM |
| MYO3A_HUMAN | Q8NEV4 | Myosin IIIA, Human | 500 | 0.25 | Binding ≤ 1μM |
| MYLK2_HUMAN | Q9H1R3 | Myosin Light Chain Kinase 2, Human | 110 | 0.28 | Binding ≤ 1μM |
| MYLK4_HUMAN | Q86YV6 | Myosin Light Chain Kinase Family Member 4, Human | 470 | 0.25 | Binding ≤ 1μM |
| MYLK_CHICK | P11799 | Myosin Light Chain Kinase, Smooth Muscle, Chick | 10 | 0.32 | Binding ≤ 1μM |
| MYLK_HUMAN | Q15746 | Myosin Light Chain Kinase, Smooth Muscle, Human | 10 | 0.32 | Binding ≤ 1μM |
| MYO3B_HUMAN | Q8WXR4 | Myosin-IIIB, Human | 300 | 0.26 | Binding ≤ 1μM |
| DMPK_HUMAN | Q09013 | Myotonin-protein Kinase, Human | 3.5 | 0.34 | Binding ≤ 1μM |
| NTRK1_HUMAN | P04629 | Nerve Growth Factor Receptor Trk-A, Human | 1.7 | 0.35 | Binding ≤ 1μM |
| NTRK2_HUMAN | Q16620 | Neurotrophic Tyrosine Kinase Receptor Type 2, Human | 3.8 | 0.34 | Binding ≤ 1μM |
| TNK1_HUMAN | Q13470 | Non-receptor Tyrosine-protein Kinase TNK1, Human | 2.5 | 0.34 | Binding ≤ 1μM |
| NTRK3_HUMAN | Q16288 | NT-3 Growth Factor Receptor, Human | 17 | 0.31 | Binding ≤ 1μM |
| NUAK1_HUMAN | O60285 | NUAK Family SNF1-like Kinase 1, Human | 4.4 | 0.33 | Binding ≤ 1μM |
| NUAK2_HUMAN | Q9H093 | NUAK Family SNF1-like Kinase 2, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| PI51A_HUMAN | Q99755 | Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human | 43 | 0.29 | Binding ≤ 1μM |
| PI42B_HUMAN | P78356 | Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human | 77 | 0.28 | Binding ≤ 1μM |
| KPB2_HUMAN | P46019 | Phosphorylase Kinase Alpha L Subunit, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| KPB1_HUMAN | P46020 | Phosphorylase Kinase Alpha M Subunit, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| KPBB_HUMAN | Q93100 | Phosphorylase Kinase Beta Subunit, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| PHKG1_HUMAN | Q16816 | Phosphorylase Kinase Gamma Subunit 1, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| PHKG2_HUMAN | P15735 | Phosphorylase Kinase Gamma Subunit 2, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| PGFRA_HUMAN | P16234 | Platelet-derived Growth Factor Receptor Alpha, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| PGFRA_MOUSE | P26618 | Platelet-derived Growth Factor Receptor Alpha, Mouse | 2 | 0.35 | Binding ≤ 1μM |
| PGFRB_HUMAN | P09619 | Platelet-derived Growth Factor Receptor Beta, Human | 1.8 | 0.35 | Binding ≤ 1μM |
| PGFRB_MOUSE | P05622 | Platelet-derived Growth Factor Receptor Beta, Mouse | 2 | 0.35 | Binding ≤ 1μM |
| KPCA_HUMAN | P17252 | Protein Kinase C Alpha, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCA_RAT | P05696 | Protein Kinase C Alpha, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCB_HUMAN | P05771 | Protein Kinase C Beta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCB_RAT | P68403 | Protein Kinase C Beta, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCD_RAT | P09215 | Protein Kinase C Delta, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCD_HUMAN | Q05655 | Protein Kinase C Delta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCE_RAT | P09216 | Protein Kinase C Epsilon, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCE_HUMAN | Q02156 | Protein Kinase C Epsilon, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCL_HUMAN | P24723 | Protein Kinase C Eta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCL_RAT | Q64617 | Protein Kinase C Eta, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCG_RAT | P63319 | Protein Kinase C Gamma, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCG_HUMAN | P05129 | Protein Kinase C Gamma, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCI_HUMAN | P41743 | Protein Kinase C Iota, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCD1_HUMAN | Q15139 | Protein Kinase C Mu, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCD3_HUMAN | O94806 | Protein Kinase C Nu, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCT_HUMAN | Q04759 | Protein Kinase C Theta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCT_RAT | Q9WTQ0 | Protein Kinase C Theta, Rat | 10 | 0.32 | Binding ≤ 1μM |
| KPCZ_HUMAN | Q05513 | Protein Kinase C Zeta, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KPCZ_RAT | P09217 | Protein Kinase C Zeta, Rat | 10 | 0.32 | Binding ≤ 1μM |
| PKN1_HUMAN | Q16512 | Protein Kinase N1, Human | 1.3 | 0.36 | Binding ≤ 1μM |
| PKN2_HUMAN | Q16513 | Protein Kinase N2, Human | 2.5 | 0.34 | Binding ≤ 1μM |
| FAK2_HUMAN | Q14289 | Protein Tyrosine Kinase 2 Beta, Human | 3.5 | 0.34 | Binding ≤ 1μM |
| MERTK_HUMAN | Q12866 | Proto-oncogene Tyrosine-protein Kinase MER, Human | 6.4 | 0.33 | Binding ≤ 1μM |
| ROS1_HUMAN | P08922 | Proto-oncogene Tyrosine-protein Kinase ROS, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| ERBB4_HUMAN | Q15303 | Receptor Protein-tyrosine Kinase ErbB-4, Human | 282 | 0.26 | Binding ≤ 1μM |
| ROCK1_HUMAN | Q13464 | Rho-associated Protein Kinase 1, Human | 1.1 | 0.36 | Binding ≤ 1μM |
| KS6B1_HUMAN | P23443 | Ribosomal Protein S6 Kinase 1, Human | 5 | 0.33 | Binding ≤ 1μM |
| KS6B2_HUMAN | Q9UBS0 | Ribosomal Protein S6 Kinase 2, Human | 5 | 0.33 | Binding ≤ 1μM |
| KS6A1_HUMAN | Q15418 | Ribosomal Protein S6 Kinase Alpha 1, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| KS6A2_HUMAN | Q15349 | Ribosomal Protein S6 Kinase Alpha 2, Human | 10 | 0.32 | Binding ≤ 1μM |
| KS6A3_HUMAN | P51812 | Ribosomal Protein S6 Kinase Alpha 3, Human | 5 | 0.33 | Binding ≤ 1μM |
| KS6A4_HUMAN | O75676 | Ribosomal Protein S6 Kinase Alpha 4, Human | 120 | 0.28 | Binding ≤ 1μM |
| KS6A5_HUMAN | O75582 | Ribosomal Protein S6 Kinase Alpha 5, Human | 20 | 0.31 | Binding ≤ 1μM |
| KS6A6_HUMAN | Q9UK32 | Ribosomal Protein S6 Kinase Alpha 6, Human | 18 | 0.31 | Binding ≤ 1μM |
| NLK_HUMAN | Q9UBE8 | Serine/threonine Protein Kinase NLK, Human | 220 | 0.27 | Binding ≤ 1μM |
| STK10_HUMAN | O94804 | Serine/threonine-protein Kinase 10, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| STK11_HUMAN | Q15831 | Serine/threonine-protein Kinase 11, Human | 61 | 0.29 | Binding ≤ 1μM |
| STK16_HUMAN | O75716 | Serine/threonine-protein Kinase 16, Human | 200 | 0.27 | Binding ≤ 1μM |
| ST17A_HUMAN | Q9UEE5 | Serine/threonine-protein Kinase 17A, Human | 14 | 0.31 | Binding ≤ 1μM |
| ST17B_HUMAN | O94768 | Serine/threonine-protein Kinase 17B, Human | 21 | 0.31 | Binding ≤ 1μM |
| SLK_HUMAN | Q9H2G2 | Serine/threonine-protein Kinase 2, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| STK24_HUMAN | Q9Y6E0 | Serine/threonine-protein Kinase 24, Human | 120 | 0.28 | Binding ≤ 1μM |
| STK25_HUMAN | O00506 | Serine/threonine-protein Kinase 25, Human | 110 | 0.28 | Binding ≤ 1μM |
| ST32B_HUMAN | Q9NY57 | Serine/threonine-protein Kinase 32B, Human | 98 | 0.28 | Binding ≤ 1μM |
| ST32C_HUMAN | Q86UX6 | Serine/threonine-protein Kinase 32C, Human | 310 | 0.26 | Binding ≤ 1μM |
| STK33_HUMAN | Q9BYT3 | Serine/threonine-protein Kinase 33, Human | 1.8 | 0.35 | Binding ≤ 1μM |
| ST38L_HUMAN | Q9Y2H1 | Serine/threonine-protein Kinase 38-like, Human | 28 | 0.30 | Binding ≤ 1μM |
| AKT1_HUMAN | P31749 | Serine/threonine-protein Kinase AKT, Human | 1.5 | 0.35 | Binding ≤ 1μM |
| AKT2_HUMAN | P31751 | Serine/threonine-protein Kinase AKT2, Human | 44 | 0.29 | Binding ≤ 1μM |
| AKT3_HUMAN | Q9Y243 | Serine/threonine-protein Kinase AKT3, Human | 0.64 | 0.37 | Binding ≤ 1μM |
| AURKA_HUMAN | O14965 | Serine/threonine-protein Kinase Aurora-A, Human | 110 | 0.28 | Binding ≤ 1μM |
| AURKB_HUMAN | Q96GD4 | Serine/threonine-protein Kinase Aurora-B, Human | 19 | 0.31 | Binding ≤ 1μM |
| AURKC_HUMAN | Q9UQB9 | Serine/threonine-protein Kinase Aurora-C, Human | 11 | 0.32 | Binding ≤ 1μM |
| MARK3_HUMAN | P27448 | Serine/threonine-protein Kinase C-TAK1, Human | 3 | 0.34 | Binding ≤ 1μM |
| CHK1_HUMAN | O14757 | Serine/threonine-protein Kinase Chk1, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| CHK2_HUMAN | O96017 | Serine/threonine-protein Kinase Chk2, Human | 27 | 0.30 | Binding ≤ 1μM |
| KPCD2_HUMAN | Q9BZL6 | Serine/threonine-protein Kinase D2, Human | 72 | 0.29 | Binding ≤ 1μM |
| DCLK1_HUMAN | O15075 | Serine/threonine-protein Kinase DCLK1, Human | 110 | 0.28 | Binding ≤ 1μM |
| DCLK2_HUMAN | Q8N568 | Serine/threonine-protein Kinase DCLK2, Human | 73 | 0.29 | Binding ≤ 1μM |
| DCLK3_HUMAN | Q9C098 | Serine/threonine-protein Kinase DCLK3, Human | 17 | 0.31 | Binding ≤ 1μM |
| GAK_HUMAN | O14976 | Serine/threonine-protein Kinase GAK, Human | 17 | 0.31 | Binding ≤ 1μM |
| LATS1_HUMAN | O95835 | Serine/threonine-protein Kinase LATS1, Human | 42 | 0.30 | Binding ≤ 1μM |
| LATS2_HUMAN | Q9NRM7 | Serine/threonine-protein Kinase LATS2, Human | 17 | 0.31 | Binding ≤ 1μM |
| MARK1_HUMAN | Q9P0L2 | Serine/threonine-protein Kinase MARK1, Human | 4 | 0.34 | Binding ≤ 1μM |
| MRCKB_HUMAN | Q9Y5S2 | Serine/threonine-protein Kinase MRCK Beta, Human | 42 | 0.30 | Binding ≤ 1μM |
| MRCKG_HUMAN | Q6DT37 | Serine/threonine-protein Kinase MRCK Gamma, Human | 37 | 0.30 | Binding ≤ 1μM |
| MRCKA_HUMAN | Q5VT25 | Serine/threonine-protein Kinase MRCK-A, Human | 57 | 0.29 | Binding ≤ 1μM |
| STK4_HUMAN | Q13043 | Serine/threonine-protein Kinase MST1, Human | 0.19 | 0.39 | Binding ≤ 1μM |
| STK3_HUMAN | Q13188 | Serine/threonine-protein Kinase MST2, Human | 0.18 | 0.39 | Binding ≤ 1μM |
| STK3_MOUSE | Q9JI10 | Serine/threonine-protein Kinase MST2, Mouse | 0.15 | 0.39 | Binding ≤ 1μM |
| MST4_HUMAN | Q9P289 | Serine/threonine-protein Kinase MST4, Human | 140 | 0.27 | Binding ≤ 1μM |
| NEK1_HUMAN | Q96PY6 | Serine/threonine-protein Kinase Nek1, Human | 860 | 0.24 | Binding ≤ 1μM |
| NEK2_HUMAN | P51955 | Serine/threonine-protein Kinase NEK2, Human | 740 | 0.25 | Binding ≤ 1μM |
| NEK5_HUMAN | Q6P3R8 | Serine/threonine-protein Kinase Nek5, Human | 810 | 0.24 | Binding ≤ 1μM |
| PAK1_HUMAN | Q13153 | Serine/threonine-protein Kinase PAK 1, Human | 0.57 | 0.37 | Binding ≤ 1μM |
| PAK2_HUMAN | Q13177 | Serine/threonine-protein Kinase PAK 2, Human | 1 | 0.36 | Binding ≤ 1μM |
| PAK3_HUMAN | O75914 | Serine/threonine-protein Kinase PAK 3, Human | 0.5 | 0.37 | Binding ≤ 1μM |
| PAK4_HUMAN | O96013 | Serine/threonine-protein Kinase PAK 4, Human | 6.3 | 0.33 | Binding ≤ 1μM |
| PAK6_HUMAN | Q9NQU5 | Serine/threonine-protein Kinase PAK6, Human | 0.4 | 0.38 | Binding ≤ 1μM |
| PAK7_HUMAN | Q9P286 | Serine/threonine-protein Kinase PAK7, Human | 1.2 | 0.36 | Binding ≤ 1μM |
| CDK16_HUMAN | Q00536 | Serine/threonine-protein Kinase PCTAIRE-1, Human | 24 | 0.30 | Binding ≤ 1μM |
| CDK17_HUMAN | Q00537 | Serine/threonine-protein Kinase PCTAIRE-2, Human | 96 | 0.28 | Binding ≤ 1μM |
| CDK18_HUMAN | Q07002 | Serine/threonine-protein Kinase PCTAIRE-3, Human | 270 | 0.26 | Binding ≤ 1μM |
| CDK14_HUMAN | O94921 | Serine/threonine-protein Kinase PFTAIRE-1, Human | 160 | 0.27 | Binding ≤ 1μM |
| PIM1_HUMAN | P11309 | Serine/threonine-protein Kinase PIM1, Human | 1.4 | 0.35 | Binding ≤ 1μM |
| PIM2_HUMAN | Q9P1W9 | Serine/threonine-protein Kinase PIM2, Human | 1.9 | 0.35 | Binding ≤ 1μM |
| PIM3_HUMAN | Q86V86 | Serine/threonine-protein Kinase PIM3, Human | 0.51 | 0.37 | Binding ≤ 1μM |
| PLK1_HUMAN | P53350 | Serine/threonine-protein Kinase PLK1, Human | 190 | 0.27 | Binding ≤ 1μM |
| PLK2_HUMAN | Q9NYY3 | Serine/threonine-protein Kinase PLK2, Human | 197 | 0.27 | Binding ≤ 1μM |
| PLK3_HUMAN | Q9H4B4 | Serine/threonine-protein Kinase PLK3, Human | 910 | 0.24 | Binding ≤ 1μM |
| PLK4_HUMAN | O00444 | Serine/threonine-protein Kinase PLK4, Human | 0.75 | 0.36 | Binding ≤ 1μM |
| PRKX_HUMAN | P51817 | Serine/threonine-protein Kinase PRKX, Human | 13 | 0.32 | Binding ≤ 1μM |
| RAF1_HUMAN | P04049 | Serine/threonine-protein Kinase RAF, Human | 140 | 0.27 | Binding ≤ 1μM |
| RIOK1_HUMAN | Q9BRS2 | Serine/threonine-protein Kinase RIO1, Human | 130 | 0.28 | Binding ≤ 1μM |
| RIOK3_HUMAN | O14730 | Serine/threonine-protein Kinase RIO3, Human | 76 | 0.28 | Binding ≤ 1μM |
| SIK1_HUMAN | P57059 | Serine/threonine-protein Kinase SIK1, Human | 2.2 | 0.35 | Binding ≤ 1μM |
| SIK2_HUMAN | Q9H0K1 | Serine/threonine-protein Kinase SIK2, Human | 1.1 | 0.36 | Binding ≤ 1μM |
| SRPK1_HUMAN | Q96SB4 | Serine/threonine-protein Kinase SRPK1, Human | 5.5 | 0.33 | Binding ≤ 1μM |
| SRPK2_HUMAN | P78362 | Serine/threonine-protein Kinase SRPK2, Human | 67 | 0.29 | Binding ≤ 1μM |
| TNI3K_HUMAN | Q59H18 | Serine/threonine-protein Kinase TNNI3K, Human | 1000 | 0.24 | Binding ≤ 1μM |
| TLK1_HUMAN | Q9UKI8 | Serine/threonine-protein Kinase Tousled-like 1, Human | 27 | 0.30 | Binding ≤ 1μM |
| TLK2_HUMAN | Q86UE8 | Serine/threonine-protein Kinase Tousled-like 2, Human | 16 | 0.31 | Binding ≤ 1μM |
| KIT_HUMAN | P10721 | Stem Cell Growth Factor Receptor, Human | 0.64 | 0.37 | Binding ≤ 1μM |
| TSSK1_HUMAN | Q9BXA7 | Testis-specific Serine/threonine-protein Kinase 1, Human | 24 | 0.30 | Binding ≤ 1μM |
| TNIK_HUMAN | Q9UKE5 | TRAF2- And NCK-interacting Kinase, Human | 4.7 | 0.33 | Binding ≤ 1μM |
| TBA1A_RAT | P68370 | Tubulin Alpha-1 Chain, Rat | 770 | 0.24 | Binding ≤ 1μM |
| ACK1_HUMAN | Q07912 | Tyrosine Kinase Non-receptor Protein 2, Human | 16 | 0.31 | Binding ≤ 1μM |
| ABL1_HUMAN | P00519 | Tyrosine-protein Kinase ABL, Human | 100 | 0.28 | Binding ≤ 1μM |
| ABL2_HUMAN | P42684 | Tyrosine-protein Kinase ABL2, Human | 100 | 0.28 | Binding ≤ 1μM |
| BLK_MOUSE | P16277 | Tyrosine-protein Kinase BLK, Mouse | 400 | 0.26 | Binding ≤ 1μM |
| BLK_HUMAN | P51451 | Tyrosine-protein Kinase BLK, Human | 15 | 0.31 | Binding ≤ 1μM |
| BMX_HUMAN | P51813 | Tyrosine-protein Kinase BMX, Human | 170 | 0.27 | Binding ≤ 1μM |
| BTK_HUMAN | Q06187 | Tyrosine-protein Kinase BTK, Human | 210 | 0.27 | Binding ≤ 1μM |
| CSK_HUMAN | P41240 | Tyrosine-protein Kinase CSK, Human | 330 | 0.26 | Binding ≤ 1μM |
| FER_HUMAN | P16591 | Tyrosine-protein Kinase FER, Human | 24 | 0.30 | Binding ≤ 1μM |
| FES_HUMAN | P07332 | Tyrosine-protein Kinase FES, Human | 23 | 0.31 | Binding ≤ 1μM |
| FGR_HUMAN | P09769 | Tyrosine-protein Kinase FGR, Human | 17 | 0.31 | Binding ≤ 1μM |
| FRK_HUMAN | P42685 | Tyrosine-protein Kinase FRK, Human | 260 | 0.26 | Binding ≤ 1μM |
| FYN_HUMAN | P06241 | Tyrosine-protein Kinase FYN, Human | 15 | 0.31 | Binding ≤ 1μM |
| HCK_HUMAN | P08631 | Tyrosine-protein Kinase HCK, Human | 12 | 0.32 | Binding ≤ 1μM |
| ITK_HUMAN | Q08881 | Tyrosine-protein Kinase ITK/TSK, Human | 19 | 0.31 | Binding ≤ 1μM |
| JAK2_HUMAN | O60674 | Tyrosine-protein Kinase JAK2, Human | 11 | 0.32 | Binding ≤ 1μM |
| JAK3_HUMAN | P52333 | Tyrosine-protein Kinase JAK3, Human | 0.15 | 0.39 | Binding ≤ 1μM |
| LCK_HUMAN | P06239 | Tyrosine-protein Kinase LCK, Human | 1.5 | 0.35 | Binding ≤ 1μM |
| LYN_HUMAN | P07948 | Tyrosine-protein Kinase Lyn, Human | 0.49 | 0.37 | Binding ≤ 1μM |
| FLT3_HUMAN | P36888 | Tyrosine-protein Kinase Receptor FLT3, Human | 1 | 0.36 | Binding ≤ 1μM |
| RET_HUMAN | P07949 | Tyrosine-protein Kinase Receptor RET, Human | 0.46 | 0.37 | Binding ≤ 1μM |
| TIE1_HUMAN | P35590 | Tyrosine-protein Kinase Receptor Tie-1, Human | 65 | 0.29 | Binding ≤ 1μM |
| TYRO3_HUMAN | Q06418 | Tyrosine-protein Kinase Receptor TYRO3, Human | 280 | 0.26 | Binding ≤ 1μM |
| UFO_HUMAN | P30530 | Tyrosine-protein Kinase Receptor UFO, Human | 6.8 | 0.33 | Binding ≤ 1μM |
| SRC_HUMAN | P12931 | Tyrosine-protein Kinase SRC, Human | 1 | 0.36 | Binding ≤ 1μM |
| SRMS_HUMAN | Q9H3Y6 | Tyrosine-protein Kinase Srms, Human | 740 | 0.25 | Binding ≤ 1μM |
| KSYK_HUMAN | P43405 | Tyrosine-protein Kinase SYK, Human | 0.1 | 0.40 | Binding ≤ 1μM |
| TIE2_HUMAN | Q02763 | Tyrosine-protein Kinase TIE-2, Human | 140 | 0.27 | Binding ≤ 1μM |
| TXK_HUMAN | P42681 | Tyrosine-protein Kinase TXK, Human | 230 | 0.27 | Binding ≤ 1μM |
| TYK2_HUMAN | P29597 | Tyrosine-protein Kinase TYK2, Human | 56 | 0.29 | Binding ≤ 1μM |
| YES_HUMAN | P07947 | Tyrosine-protein Kinase YES, Human | 49 | 0.29 | Binding ≤ 1μM |
| ZAP70_HUMAN | P43403 | Tyrosine-protein Kinase ZAP-70, Human | 44 | 0.29 | Binding ≤ 1μM |
| ULK3_MOUSE | Q3U3Q1 | ULK3 Kinase, Mouse | 3 | 0.34 | Binding ≤ 1μM |
| VGFR1_MOUSE | P35969 | Vascular Endothelial Growth Factor Receptor 1, Mouse | 14 | 0.31 | Binding ≤ 1μM |
| VGFR1_HUMAN | P17948 | Vascular Endothelial Growth Factor Receptor 1, Human | 150 | 0.27 | Binding ≤ 1μM |
| VGFR2_HUMAN | P35968 | Vascular Endothelial Growth Factor Receptor 2, Human | 1.2 | 0.36 | Binding ≤ 1μM |
| VGFR2_MOUSE | P35918 | Vascular Endothelial Growth Factor Receptor 2, Mouse | 14 | 0.31 | Binding ≤ 1μM |
| VGFR3_MOUSE | P35917 | Vascular Endothelial Growth Factor Receptor 3, Mouse | 14 | 0.31 | Binding ≤ 1μM |
| VGFR3_HUMAN | P35916 | Vascular Endothelial Growth Factor Receptor 3, Human | 1.9 | 0.35 | Binding ≤ 1μM |
| PDPK1_HUMAN | O15530 | 3-phosphoinositide Dependent Protein Kinase-1, Human | 1.7 | 0.35 | Binding ≤ 10μM |
| ACVR1_HUMAN | Q04771 | Activin Receptor Type-1, Human | 470 | 0.25 | Binding ≤ 10μM |
| ACV1B_HUMAN | P36896 | Activin Receptor Type-1B, Human | 680 | 0.25 | Binding ≤ 10μM |
| AVR2B_HUMAN | Q13705 | Activin Receptor Type-2B, Human | 4600 | 0.21 | Binding ≤ 10μM |
| AAK1_HUMAN | Q2M2I8 | Adaptor-associated Kinase, Human | 1.2 | 0.36 | Binding ≤ 10μM |
| ALK_HUMAN | Q9UM73 | ALK Tyrosine Kinase Receptor, Human | 32 | 0.30 | Binding ≤ 10μM |
| AAPK1_HUMAN | Q13131 | AMP-activated Protein Kinase, Alpha-1 Subunit, Human | 3.7 | 0.34 | Binding ≤ 10μM |
| AAPK2_HUMAN | P54646 | AMP-activated Protein Kinase, Alpha-2 Subunit, Human | 12 | 0.32 | Binding ≤ 10μM |
| ANKK1_HUMAN | Q8NFD2 | Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human | 270 | 0.26 | Binding ≤ 10μM |
| BMP2K_HUMAN | Q9NSY1 | BMP-2-inducible Protein Kinase, Human | 3.7 | 0.34 | Binding ≤ 10μM |
| BMR1A_HUMAN | P36894 | Bone Morphogenetic Protein Receptor Type-1A, Human | 3700 | 0.22 | Binding ≤ 10μM |
| BRSK1_HUMAN | Q8TDC3 | BR Serine/threonine-protein Kinase 1, Human | 26 | 0.30 | Binding ≤ 10μM |
| BRSK2_HUMAN | Q8IWQ3 | BR Serine/threonine-protein Kinase 2, Human | 3.5 | 0.34 | Binding ≤ 10μM |
| MK08_HUMAN | P45983 | C-Jun N-terminal Kinase 1, Human | 220 | 0.27 | Binding ≤ 10μM |
| MK09_HUMAN | P45984 | C-Jun N-terminal Kinase 2, Human | 1100 | 0.24 | Binding ≤ 10μM |
| MK10_HUMAN | P53779 | C-Jun N-terminal Kinase 3, Human | 110 | 0.28 | Binding ≤ 10μM |
| KCC1A_HUMAN | Q14012 | CaM Kinase I Alpha, Human | 27 | 0.30 | Binding ≤ 10μM |
| KCC1D_HUMAN | Q8IU85 | CaM Kinase I Delta, Human | 1.1 | 0.36 | Binding ≤ 10μM |
| KCC1G_HUMAN | Q96NX5 | CaM Kinase I Gamma, Human | 23 | 0.31 | Binding ≤ 10μM |
| KCC2A_RAT | P11275 | CaM Kinase II Alpha, Rat | 2 | 0.35 | Binding ≤ 10μM |
| KCC2A_HUMAN | Q9UQM7 | CaM Kinase II Alpha, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KCC2A_MOUSE | P11798 | CaM Kinase II Alpha, Mouse | 6 | 0.33 | Binding ≤ 10μM |
| KCC2B_HUMAN | Q13554 | CaM Kinase II Beta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KCC2B_MOUSE | P28652 | CaM Kinase II Beta, Mouse | 6 | 0.33 | Binding ≤ 10μM |
| KCC2D_HUMAN | Q13557 | CaM Kinase II Delta, Human | 0.32 | 0.38 | Binding ≤ 10μM |
| KCC2G_HUMAN | Q13555 | CaM Kinase II Gamma, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| KCC2G_MOUSE | Q923T9 | CaM Kinase II Gamma, Mouse | 6 | 0.33 | Binding ≤ 10μM |
| KCC4_HUMAN | Q16566 | CaM Kinase IV, Human | 4 | 0.34 | Binding ≤ 10μM |
| KKCC1_HUMAN | Q8N5S9 | CaM-kinase Kinase Alpha, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KKCC2_HUMAN | Q96RR4 | CaM-kinase Kinase Beta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KAPCA_BOVIN | P00517 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin | 100 | 0.28 | Binding ≤ 10μM |
| KAPCA_RAT | P27791 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat | 120 | 0.28 | Binding ≤ 10μM |
| KAPCA_MOUSE | P05132 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse | 4 | 0.34 | Binding ≤ 10μM |
| Q95J97_RABIT | Q95J97 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit | 80 | 0.28 | Binding ≤ 10μM |
| KAPCA_HUMAN | P17612 | CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human | 0.9 | 0.36 | Binding ≤ 10μM |
| KAPCB_MOUSE | P68181 | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse | 4 | 0.34 | Binding ≤ 10μM |
| KAPCB_BOVIN | P05131 | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin | 100 | 0.28 | Binding ≤ 10μM |
| KAPCB_HUMAN | P22694 | CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human | 0.9 | 0.36 | Binding ≤ 10μM |
| KAP2_BOVIN | P00515 | CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin | 100 | 0.28 | Binding ≤ 10μM |
| KAPCG_HUMAN | P22612 | CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human | 0.9 | 0.36 | Binding ≤ 10μM |
| KC1A_HUMAN | P48729 | Casein Kinase I Alpha, Human | 1400 | 0.23 | Binding ≤ 10μM |
| KC1A_MOUSE | Q8BK63 | Casein Kinase I Alpha, Mouse | 1400 | 0.23 | Binding ≤ 10μM |
| KC1D_HUMAN | P48730 | Casein Kinase I Delta, Human | 1400 | 0.23 | Binding ≤ 10μM |
| KC1D_MOUSE | Q9DC28 | Casein Kinase I Delta, Mouse | 1400 | 0.23 | Binding ≤ 10μM |
| KC1E_HUMAN | P49674 | Casein Kinase I Epsilon, Human | 1400 | 0.23 | Binding ≤ 10μM |
| KC1E_MOUSE | Q9JMK2 | Casein Kinase I Epsilon, Mouse | 1400 | 0.23 | Binding ≤ 10μM |
| KC1G1_HUMAN | Q9HCP0 | Casein Kinase I Gamma 1, Human | 1400 | 0.23 | Binding ≤ 10μM |
| KC1G1_MOUSE | Q8BTH8 | Casein Kinase I Gamma 1, Mouse | 1400 | 0.23 | Binding ≤ 10μM |
| KC1G2_HUMAN | P78368 | Casein Kinase I Gamma 2, Human | 1400 | 0.23 | Binding ≤ 10μM |
| KC1AL_HUMAN | Q8N752 | Casein Kinase I Isoform Alpha-like, Human | 250 | 0.26 | Binding ≤ 10μM |
| CSK21_HUMAN | P68400 | Casein Kinase II Alpha, Human | 3400 | 0.22 | Binding ≤ 10μM |
| CSK21_RAT | P19139 | Casein Kinase II Alpha, Rat | 7000 | 0.21 | Binding ≤ 10μM |
| CSK22_HUMAN | P19784 | Casein Kinase II Alpha (prime), Human | 3400 | 0.22 | Binding ≤ 10μM |
| CSK2B_RAT | P67874 | Casein Kinase II Beta, Rat | 7000 | 0.21 | Binding ≤ 10μM |
| CSK2B_HUMAN | P67870 | Casein Kinase II Beta, Human | 3400 | 0.22 | Binding ≤ 10μM |
| CDK19_HUMAN | Q9BWU1 | Cell Division Cycle 2-like Protein Kinase 6, Human | 190 | 0.27 | Binding ≤ 10μM |
| CDK8_HUMAN | P49336 | Cell Division Protein Kinase 8, Human | 510 | 0.25 | Binding ≤ 10μM |
| KGP1_BOVIN | P00516 | CGMP-dependent Protein Kinase 1 Alpha, Bovin | 18 | 0.31 | Binding ≤ 10μM |
| KGP1_HUMAN | Q13976 | CGMP-dependent Protein Kinase 1 Beta, Human | 32 | 0.30 | Binding ≤ 10μM |
| KGP2_HUMAN | Q13237 | CGMP-dependent Protein Kinase 2, Human | 16 | 0.31 | Binding ≤ 10μM |
| CTRO_HUMAN | O14578 | Citron Rho-interacting Kinase, Human | 340 | 0.26 | Binding ≤ 10μM |
| CDK1_HUMAN | P06493 | Cyclin-dependent Kinase 1, Human | 0.4 | 0.38 | Binding ≤ 10μM |
| CDK1_MOUSE | P11440 | Cyclin-dependent Kinase 1, Mouse | 8 | 0.32 | Binding ≤ 10μM |
| CDK2_HUMAN | P24941 | Cyclin-dependent Kinase 2, Human | 0.36 | 0.38 | Binding ≤ 10μM |
| CDK3_HUMAN | Q00526 | Cyclin-dependent Kinase 3, Human | 30 | 0.30 | Binding ≤ 10μM |
| CDK4_HUMAN | P11802 | Cyclin-dependent Kinase 4, Human | 18.3 | 0.31 | Binding ≤ 10μM |
| Z104295 | Z104295 | Cyclin-dependent Kinase 4/cyclin D1 | 59 | 0.29 | Binding ≤ 10μM |
| CDK5_HUMAN | Q00535 | Cyclin-dependent Kinase 5, Human | 3.8 | 0.34 | Binding ≤ 10μM |
| Z104294 | Z104294 | Cyclin-dependent Kinase 5/CDK5 Activator 1 | 10 | 0.32 | Binding ≤ 10μM |
| CDK6_HUMAN | Q00534 | Cyclin-dependent Kinase 6, Human | 116 | 0.28 | Binding ≤ 10μM |
| CDK7_HUMAN | P50613 | Cyclin-dependent Kinase 7, Human | 45 | 0.29 | Binding ≤ 10μM |
| CDK9_HUMAN | P50750 | Cyclin-dependent Kinase 9, Human | 100 | 0.28 | Binding ≤ 10μM |
| DAPK1_HUMAN | P53355 | Death-associated Protein Kinase 1, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| DAPK2_HUMAN | Q9UIK4 | Death-associated Protein Kinase 2, Human | 1.6 | 0.35 | Binding ≤ 10μM |
| DAPK3_HUMAN | O43293 | Death-associated Protein Kinase 3, Human | 1 | 0.36 | Binding ≤ 10μM |
| DDR2_HUMAN | Q16832 | Discoidin Domain-containing Receptor 2, Human | 42 | 0.30 | Binding ≤ 10μM |
| MP2K1_HUMAN | Q02750 | Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human | 1000 | 0.24 | Binding ≤ 10μM |
| MP2K2_HUMAN | P36507 | Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human | 28 | 0.30 | Binding ≤ 10μM |
| MP2K3_HUMAN | P46734 | Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human | 5 | 0.33 | Binding ≤ 10μM |
| MP2K4_HUMAN | P45985 | Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human | 1 | 0.36 | Binding ≤ 10μM |
| MP2K6_HUMAN | P52564 | Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human | 1 | 0.36 | Binding ≤ 10μM |
| CLK2_HUMAN | P49760 | Dual Specificity Protein Kinase CLK2, Human | 12 | 0.32 | Binding ≤ 10μM |
| CLK3_HUMAN | P49761 | Dual Specificity Protein Kinase CLK3, Human | 3500 | 0.22 | Binding ≤ 10μM |
| CLK4_HUMAN | Q9HAZ1 | Dual Specificity Protein Kinase CLK4, Human | 15 | 0.31 | Binding ≤ 10μM |
| TTK_HUMAN | P33981 | Dual Specificity Protein Kinase TTK, Human | 100 | 0.28 | Binding ≤ 10μM |
| TESK1_HUMAN | Q15569 | Dual Specificity Testis-specific Protein Kinase 1, Human | 320 | 0.26 | Binding ≤ 10μM |
| DYR1B_HUMAN | Q9Y463 | Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human | 28 | 0.30 | Binding ≤ 10μM |
| CLK1_HUMAN | P49759 | Dual Specificty Protein Kinase CLK1, Human | 27 | 0.30 | Binding ≤ 10μM |
| EPHA1_HUMAN | P21709 | Ephrin Type-A Receptor 1, Human | 300 | 0.26 | Binding ≤ 10μM |
| EPHA2_HUMAN | P29317 | Ephrin Type-A Receptor 2, Human | 1200 | 0.24 | Binding ≤ 10μM |
| EPHA3_HUMAN | P29320 | Ephrin Type-A Receptor 3, Human | 27 | 0.30 | Binding ≤ 10μM |
| EPHA4_HUMAN | P54764 | Ephrin Type-A Receptor 4, Human | 290 | 0.26 | Binding ≤ 10μM |
| EPHA5_HUMAN | P54756 | Ephrin Type-A Receptor 5, Human | 150 | 0.27 | Binding ≤ 10μM |
| EPHA6_HUMAN | Q9UF33 | Ephrin Type-A Receptor 6, Human | 240 | 0.26 | Binding ≤ 10μM |
| EPHA7_HUMAN | Q15375 | Ephrin Type-A Receptor 7, Human | 630 | 0.25 | Binding ≤ 10μM |
| EPHA8_HUMAN | P29322 | Ephrin Type-A Receptor 8, Human | 190 | 0.27 | Binding ≤ 10μM |
| EPHB1_HUMAN | P54762 | Ephrin Type-B Receptor 1, Human | 240 | 0.26 | Binding ≤ 10μM |
| EPHB2_HUMAN | P29323 | Ephrin Type-B Receptor 2, Human | 2100 | 0.23 | Binding ≤ 10μM |
| EPHB4_HUMAN | P54760 | Ephrin Type-B Receptor 4, Human | 233 | 0.27 | Binding ≤ 10μM |
| EGFR_HUMAN | P00533 | Epidermal Growth Factor Receptor ErbB1, Human | 100 | 0.28 | Binding ≤ 10μM |
| DDR1_HUMAN | Q08345 | Epithelial Discoidin Domain-containing Receptor 1, Human | 19 | 0.31 | Binding ≤ 10μM |
| E2AK4_HUMAN | Q9P2K8 | Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human | 16 | 0.31 | Binding ≤ 10μM |
| FGFR1_HUMAN | P11362 | Fibroblast Growth Factor Receptor 1, Human | 420 | 0.26 | Binding ≤ 10μM |
| FGFR2_HUMAN | P21802 | Fibroblast Growth Factor Receptor 2, Human | 100 | 0.28 | Binding ≤ 10μM |
| FGFR3_HUMAN | P22607 | Fibroblast Growth Factor Receptor 3, Human | 110 | 0.28 | Binding ≤ 10μM |
| FGFR4_HUMAN | P22455 | Fibroblast Growth Factor Receptor 4, Human | 250 | 0.26 | Binding ≤ 10μM |
| FAK1_HUMAN | Q05397 | Focal Adhesion Kinase 1, Human | 64 | 0.29 | Binding ≤ 10μM |
| CCNE1_HUMAN | P24864 | G1/S-specific Cyclin E1, Human | 12 | 0.32 | Binding ≤ 10μM |
| CCNE2_HUMAN | O96020 | G1/S-specific Cyclin E2, Human | 12 | 0.32 | Binding ≤ 10μM |
| CCNB1_HUMAN | P14635 | G2/mitotic-specific Cyclin B1, Human | 12 | 0.32 | Binding ≤ 10μM |
| CCNB2_HUMAN | O95067 | G2/mitotic-specific Cyclin B2, Human | 12 | 0.32 | Binding ≤ 10μM |
| CCNB3_HUMAN | Q8WWL7 | G2/mitotic-specific Cyclin B3, Human | 12 | 0.32 | Binding ≤ 10μM |
| GSK3A_HUMAN | P49840 | Glycogen Synthase Kinase-3 Alpha, Human | 12 | 0.32 | Binding ≤ 10μM |
| GSK3B_HUMAN | P49841 | Glycogen Synthase Kinase-3 Beta, Human | 12 | 0.32 | Binding ≤ 10μM |
| MET_HUMAN | P08581 | Hepatocyte Growth Factor Receptor, Human | 103 | 0.28 | Binding ≤ 10μM |
| HIPK1_HUMAN | Q86Z02 | Homeodomain-interacting Protein Kinase 1, Human | 2639 | 0.22 | Binding ≤ 10μM |
| IKKA_HUMAN | O15111 | Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human | 233 | 0.27 | Binding ≤ 10μM |
| IKKB_HUMAN | O14920 | Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human | 1410 | 0.23 | Binding ≤ 10μM |
| IKKE_HUMAN | Q14164 | Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human | 5.1 | 0.33 | Binding ≤ 10μM |
| INSR_HUMAN | P06213 | Insulin Receptor, Human | 110 | 0.28 | Binding ≤ 10μM |
| INSR_MOUSE | P15208 | Insulin Receptor, Mouse | 200 | 0.27 | Binding ≤ 10μM |
| INSRR_HUMAN | P14616 | Insulin Receptor-related Protein, Human | 81 | 0.28 | Binding ≤ 10μM |
| IGF1R_HUMAN | P08069 | Insulin-like Growth Factor I Receptor, Human | 1325 | 0.24 | Binding ≤ 10μM |
| E2AK2_HUMAN | P19525 | Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human | 360 | 0.26 | Binding ≤ 10μM |
| IRAK3_HUMAN | Q9Y616 | Interleukin-1 Receptor-associated Kinase 3, Human | 13 | 0.32 | Binding ≤ 10μM |
| IRAK4_HUMAN | Q9NWZ3 | Interleukin-1 Receptor-associated Kinase 4, Human | 34 | 0.30 | Binding ≤ 10μM |
| LTK_HUMAN | P29376 | Leukocyte Tyrosine Kinase Receptor, Human | 37 | 0.30 | Binding ≤ 10μM |
| LIMK1_HUMAN | P53667 | LIM Domain Kinase 1, Human | 480 | 0.25 | Binding ≤ 10μM |
| LIMK2_HUMAN | P53671 | LIM Domain Kinase 2, Human | 9200 | 0.20 | Binding ≤ 10μM |
| SYK_HUMAN | Q15046 | Lysyl-tRNA Synthetase, Human | 9 | 0.32 | Binding ≤ 10μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 12 | 0.32 | Binding ≤ 10μM |
| MK03_HUMAN | P27361 | MAP Kinase ERK1, Human | 1310 | 0.24 | Binding ≤ 10μM |
| MK01_HUMAN | P28482 | MAP Kinase ERK2, Human | 1 | 0.36 | Binding ≤ 10μM |
| MK14_HUMAN | Q16539 | MAP Kinase P38 Alpha, Human | 1000 | 0.24 | Binding ≤ 10μM |
| MK11_HUMAN | Q15759 | MAP Kinase P38 Beta, Human | 1000 | 0.24 | Binding ≤ 10μM |
| MK13_HUMAN | O15264 | MAP Kinase P38 Delta, Human | 1000 | 0.24 | Binding ≤ 10μM |
| MK12_HUMAN | P53778 | MAP Kinase P38 Gamma, Human | 1000 | 0.24 | Binding ≤ 10μM |
| MKNK2_HUMAN | Q9HBH9 | MAP Kinase Signal-integrating Kinase 2, Human | 17 | 0.31 | Binding ≤ 10μM |
| MAPK2_HUMAN | P49137 | MAP Kinase-activated Protein Kinase 2, Human | 110 | 0.28 | Binding ≤ 10μM |
| MKNK1_HUMAN | Q9BUB5 | MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human | 170 | 0.27 | Binding ≤ 10μM |
| MARK2_HUMAN | Q7KZI7 | MAP/microtubule Affinity-regulating Kinase 2, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| MARK4_HUMAN | Q96L34 | MAP/microtubule Affinity-regulating Kinase 4, Human | 5.4 | 0.33 | Binding ≤ 10μM |
| MELK_HUMAN | Q14680 | Maternal Embryonic Leucine Zipper Kinase, Human | 33 | 0.30 | Binding ≤ 10μM |
| MINK1_HUMAN | Q8N4C8 | Misshapen-like Kinase 1, Human | 0.49 | 0.37 | Binding ≤ 10μM |
| MK15_HUMAN | Q8TD08 | Mitogen-activated Protein Kinase 15, Human | 35 | 0.30 | Binding ≤ 10μM |
| MK07_HUMAN | Q13164 | Mitogen-activated Protein Kinase 7, Human | 1600 | 0.23 | Binding ≤ 10μM |
| M3K10_HUMAN | Q02779 | Mitogen-activated Protein Kinase Kinase Kinase 10, Human | 52 | 0.29 | Binding ≤ 10μM |
| M3K11_HUMAN | Q16584 | Mitogen-activated Protein Kinase Kinase Kinase 11, Human | 20 | 0.31 | Binding ≤ 10μM |
| M3K14_HUMAN | Q99558 | Mitogen-activated Protein Kinase Kinase Kinase 14, Human | 2300 | 0.23 | Binding ≤ 10μM |
| M3K4_HUMAN | Q9Y6R4 | Mitogen-activated Protein Kinase Kinase Kinase 4, Human | 1200 | 0.24 | Binding ≤ 10μM |
| M3K5_HUMAN | Q99683 | Mitogen-activated Protein Kinase Kinase Kinase 5, Human | 1000 | 0.24 | Binding ≤ 10μM |
| M3K7_HUMAN | O43318 | Mitogen-activated Protein Kinase Kinase Kinase 7, Human | 35 | 0.30 | Binding ≤ 10μM |
| TAB1_HUMAN | Q15750 | Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1, Human | 35 | 0.30 | Binding ≤ 10μM |
| M3K9_HUMAN | P80192 | Mitogen-activated Protein Kinase Kinase Kinase 9, Human | 10 | 0.32 | Binding ≤ 10μM |
| M4K1_HUMAN | Q92918 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human | 4.3 | 0.33 | Binding ≤ 10μM |
| M4K3_HUMAN | Q8IVH8 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human | 8.2 | 0.32 | Binding ≤ 10μM |
| M4K4_HUMAN | O95819 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human | 24 | 0.30 | Binding ≤ 10μM |
| M4K5_HUMAN | Q9Y4K4 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human | 18 | 0.31 | Binding ≤ 10μM |
| MUSK_HUMAN | O15146 | Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human | 86 | 0.28 | Binding ≤ 10μM |
| MYO3A_HUMAN | Q8NEV4 | Myosin IIIA, Human | 500 | 0.25 | Binding ≤ 10μM |
| MYLK2_HUMAN | Q9H1R3 | Myosin Light Chain Kinase 2, Human | 110 | 0.28 | Binding ≤ 10μM |
| MYLK4_HUMAN | Q86YV6 | Myosin Light Chain Kinase Family Member 4, Human | 470 | 0.25 | Binding ≤ 10μM |
| MYLK_CHICK | P11799 | Myosin Light Chain Kinase, Smooth Muscle, Chick | 10 | 0.32 | Binding ≤ 10μM |
| MYLK_HUMAN | Q15746 | Myosin Light Chain Kinase, Smooth Muscle, Human | 10 | 0.32 | Binding ≤ 10μM |
| MYO3B_HUMAN | Q8WXR4 | Myosin-IIIB, Human | 300 | 0.26 | Binding ≤ 10μM |
| DMPK_HUMAN | Q09013 | Myotonin-protein Kinase, Human | 3.5 | 0.34 | Binding ≤ 10μM |
| NTRK1_HUMAN | P04629 | Nerve Growth Factor Receptor Trk-A, Human | 1.7 | 0.35 | Binding ≤ 10μM |
| NTRK2_HUMAN | Q16620 | Neurotrophic Tyrosine Kinase Receptor Type 2, Human | 3.8 | 0.34 | Binding ≤ 10μM |
| TNK1_HUMAN | Q13470 | Non-receptor Tyrosine-protein Kinase TNK1, Human | 2.5 | 0.34 | Binding ≤ 10μM |
| NTRK3_HUMAN | Q16288 | NT-3 Growth Factor Receptor, Human | 17 | 0.31 | Binding ≤ 10μM |
| NUAK1_HUMAN | O60285 | NUAK Family SNF1-like Kinase 1, Human | 4.4 | 0.33 | Binding ≤ 10μM |
| NUAK2_HUMAN | Q9H093 | NUAK Family SNF1-like Kinase 2, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| PI51A_HUMAN | Q99755 | Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human | 43 | 0.29 | Binding ≤ 10μM |
| PI42B_HUMAN | P78356 | Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human | 77 | 0.28 | Binding ≤ 10μM |
| KPB2_HUMAN | P46019 | Phosphorylase Kinase Alpha L Subunit, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| KPB1_HUMAN | P46020 | Phosphorylase Kinase Alpha M Subunit, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| KPBB_HUMAN | Q93100 | Phosphorylase Kinase Beta Subunit, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| PHKG1_HUMAN | Q16816 | Phosphorylase Kinase Gamma Subunit 1, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| PHKG2_HUMAN | P15735 | Phosphorylase Kinase Gamma Subunit 2, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| PGFRA_HUMAN | P16234 | Platelet-derived Growth Factor Receptor Alpha, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| PGFRA_MOUSE | P26618 | Platelet-derived Growth Factor Receptor Alpha, Mouse | 2 | 0.35 | Binding ≤ 10μM |
| PGFRB_MOUSE | P05622 | Platelet-derived Growth Factor Receptor Beta, Mouse | 2 | 0.35 | Binding ≤ 10μM |
| PGFRB_HUMAN | P09619 | Platelet-derived Growth Factor Receptor Beta, Human | 1.8 | 0.35 | Binding ≤ 10μM |
| KPCA_RAT | P05696 | Protein Kinase C Alpha, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCA_HUMAN | P17252 | Protein Kinase C Alpha, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCB_HUMAN | P05771 | Protein Kinase C Beta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCB_RAT | P68403 | Protein Kinase C Beta, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCD_HUMAN | Q05655 | Protein Kinase C Delta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCD_RAT | P09215 | Protein Kinase C Delta, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCE_RAT | P09216 | Protein Kinase C Epsilon, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCE_HUMAN | Q02156 | Protein Kinase C Epsilon, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCL_RAT | Q64617 | Protein Kinase C Eta, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCL_HUMAN | P24723 | Protein Kinase C Eta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCG_RAT | P63319 | Protein Kinase C Gamma, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCG_HUMAN | P05129 | Protein Kinase C Gamma, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCI_HUMAN | P41743 | Protein Kinase C Iota, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCD1_HUMAN | Q15139 | Protein Kinase C Mu, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCD3_HUMAN | O94806 | Protein Kinase C Nu, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCT_HUMAN | Q04759 | Protein Kinase C Theta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCT_RAT | Q9WTQ0 | Protein Kinase C Theta, Rat | 10 | 0.32 | Binding ≤ 10μM |
| KPCZ_HUMAN | Q05513 | Protein Kinase C Zeta, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KPCZ_RAT | P09217 | Protein Kinase C Zeta, Rat | 10 | 0.32 | Binding ≤ 10μM |
| PKN1_HUMAN | Q16512 | Protein Kinase N1, Human | 1.3 | 0.36 | Binding ≤ 10μM |
| PKN2_HUMAN | Q16513 | Protein Kinase N2, Human | 2.5 | 0.34 | Binding ≤ 10μM |
| P90584_PLAFA | P90584 | Protein Kinase Pfmrk, Plafa | 4000 | 0.22 | Binding ≤ 10μM |
| FAK2_HUMAN | Q14289 | Protein Tyrosine Kinase 2 Beta, Human | 3.5 | 0.34 | Binding ≤ 10μM |
| MERTK_HUMAN | Q12866 | Proto-oncogene Tyrosine-protein Kinase MER, Human | 6.4 | 0.33 | Binding ≤ 10μM |
| ROS1_HUMAN | P08922 | Proto-oncogene Tyrosine-protein Kinase ROS, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| ERBB4_HUMAN | Q15303 | Receptor Protein-tyrosine Kinase ErbB-4, Human | 282 | 0.26 | Binding ≤ 10μM |
| ROCK1_HUMAN | Q13464 | Rho-associated Protein Kinase 1, Human | 1.1 | 0.36 | Binding ≤ 10μM |
| KS6B1_HUMAN | P23443 | Ribosomal Protein S6 Kinase 1, Human | 5 | 0.33 | Binding ≤ 10μM |
| KS6B2_HUMAN | Q9UBS0 | Ribosomal Protein S6 Kinase 2, Human | 5 | 0.33 | Binding ≤ 10μM |
| KS6A1_HUMAN | Q15418 | Ribosomal Protein S6 Kinase Alpha 1, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| KS6A2_HUMAN | Q15349 | Ribosomal Protein S6 Kinase Alpha 2, Human | 10 | 0.32 | Binding ≤ 10μM |
| KS6A3_HUMAN | P51812 | Ribosomal Protein S6 Kinase Alpha 3, Human | 5 | 0.33 | Binding ≤ 10μM |
| KS6A4_HUMAN | O75676 | Ribosomal Protein S6 Kinase Alpha 4, Human | 120 | 0.28 | Binding ≤ 10μM |
| KS6A5_HUMAN | O75582 | Ribosomal Protein S6 Kinase Alpha 5, Human | 20 | 0.31 | Binding ≤ 10μM |
| KS6A6_HUMAN | Q9UK32 | Ribosomal Protein S6 Kinase Alpha 6, Human | 18 | 0.31 | Binding ≤ 10μM |
| NLK_HUMAN | Q9UBE8 | Serine/threonine Protein Kinase NLK, Human | 220 | 0.27 | Binding ≤ 10μM |
| STK10_HUMAN | O94804 | Serine/threonine-protein Kinase 10, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| STK11_HUMAN | Q15831 | Serine/threonine-protein Kinase 11, Human | 61 | 0.29 | Binding ≤ 10μM |
| STK16_HUMAN | O75716 | Serine/threonine-protein Kinase 16, Human | 200 | 0.27 | Binding ≤ 10μM |
| ST17A_HUMAN | Q9UEE5 | Serine/threonine-protein Kinase 17A, Human | 14 | 0.31 | Binding ≤ 10μM |
| ST17B_HUMAN | O94768 | Serine/threonine-protein Kinase 17B, Human | 21 | 0.31 | Binding ≤ 10μM |
| SLK_HUMAN | Q9H2G2 | Serine/threonine-protein Kinase 2, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| STK24_HUMAN | Q9Y6E0 | Serine/threonine-protein Kinase 24, Human | 120 | 0.28 | Binding ≤ 10μM |
| STK25_HUMAN | O00506 | Serine/threonine-protein Kinase 25, Human | 110 | 0.28 | Binding ≤ 10μM |
| ST32B_HUMAN | Q9NY57 | Serine/threonine-protein Kinase 32B, Human | 98 | 0.28 | Binding ≤ 10μM |
| ST32C_HUMAN | Q86UX6 | Serine/threonine-protein Kinase 32C, Human | 310 | 0.26 | Binding ≤ 10μM |
| STK33_HUMAN | Q9BYT3 | Serine/threonine-protein Kinase 33, Human | 1.8 | 0.35 | Binding ≤ 10μM |
| STK36_HUMAN | Q9NRP7 | Serine/threonine-protein Kinase 36, Human | 2900 | 0.22 | Binding ≤ 10μM |
| ST38L_HUMAN | Q9Y2H1 | Serine/threonine-protein Kinase 38-like, Human | 28 | 0.30 | Binding ≤ 10μM |
| AKT1_HUMAN | P31749 | Serine/threonine-protein Kinase AKT, Human | 1.5 | 0.35 | Binding ≤ 10μM |
| AKT2_HUMAN | P31751 | Serine/threonine-protein Kinase AKT2, Human | 44 | 0.29 | Binding ≤ 10μM |
| AKT3_HUMAN | Q9Y243 | Serine/threonine-protein Kinase AKT3, Human | 0.64 | 0.37 | Binding ≤ 10μM |
| AURKA_HUMAN | O14965 | Serine/threonine-protein Kinase Aurora-A, Human | 110 | 0.28 | Binding ≤ 10μM |
| AURKB_HUMAN | Q96GD4 | Serine/threonine-protein Kinase Aurora-B, Human | 19 | 0.31 | Binding ≤ 10μM |
| AURKC_HUMAN | Q9UQB9 | Serine/threonine-protein Kinase Aurora-C, Human | 11 | 0.32 | Binding ≤ 10μM |
| MARK3_HUMAN | P27448 | Serine/threonine-protein Kinase C-TAK1, Human | 3 | 0.34 | Binding ≤ 10μM |
| CHK1_HUMAN | O14757 | Serine/threonine-protein Kinase Chk1, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| CHK2_HUMAN | O96017 | Serine/threonine-protein Kinase Chk2, Human | 27 | 0.30 | Binding ≤ 10μM |
| KPCD2_HUMAN | Q9BZL6 | Serine/threonine-protein Kinase D2, Human | 72 | 0.29 | Binding ≤ 10μM |
| DCLK1_HUMAN | O15075 | Serine/threonine-protein Kinase DCLK1, Human | 110 | 0.28 | Binding ≤ 10μM |
| DCLK2_HUMAN | Q8N568 | Serine/threonine-protein Kinase DCLK2, Human | 73 | 0.29 | Binding ≤ 10μM |
| DCLK3_HUMAN | Q9C098 | Serine/threonine-protein Kinase DCLK3, Human | 17 | 0.31 | Binding ≤ 10μM |
| GAK_HUMAN | O14976 | Serine/threonine-protein Kinase GAK, Human | 17 | 0.31 | Binding ≤ 10μM |
| LATS1_HUMAN | O95835 | Serine/threonine-protein Kinase LATS1, Human | 42 | 0.30 | Binding ≤ 10μM |
| LATS2_HUMAN | Q9NRM7 | Serine/threonine-protein Kinase LATS2, Human | 17 | 0.31 | Binding ≤ 10μM |
| MARK1_HUMAN | Q9P0L2 | Serine/threonine-protein Kinase MARK1, Human | 4 | 0.34 | Binding ≤ 10μM |
| MRCKB_HUMAN | Q9Y5S2 | Serine/threonine-protein Kinase MRCK Beta, Human | 42 | 0.30 | Binding ≤ 10μM |
| MRCKG_HUMAN | Q6DT37 | Serine/threonine-protein Kinase MRCK Gamma, Human | 37 | 0.30 | Binding ≤ 10μM |
| MRCKA_HUMAN | Q5VT25 | Serine/threonine-protein Kinase MRCK-A, Human | 57 | 0.29 | Binding ≤ 10μM |
| STK4_HUMAN | Q13043 | Serine/threonine-protein Kinase MST1, Human | 0.19 | 0.39 | Binding ≤ 10μM |
| STK3_MOUSE | Q9JI10 | Serine/threonine-protein Kinase MST2, Mouse | 0.15 | 0.39 | Binding ≤ 10μM |
| STK3_HUMAN | Q13188 | Serine/threonine-protein Kinase MST2, Human | 0.18 | 0.39 | Binding ≤ 10μM |
| MST4_HUMAN | Q9P289 | Serine/threonine-protein Kinase MST4, Human | 140 | 0.27 | Binding ≤ 10μM |
| NEK1_HUMAN | Q96PY6 | Serine/threonine-protein Kinase Nek1, Human | 860 | 0.24 | Binding ≤ 10μM |
| NEK2_HUMAN | P51955 | Serine/threonine-protein Kinase NEK2, Human | 740 | 0.25 | Binding ≤ 10μM |
| NEK5_HUMAN | Q6P3R8 | Serine/threonine-protein Kinase Nek5, Human | 810 | 0.24 | Binding ≤ 10μM |
| NEK7_HUMAN | Q8TDX7 | Serine/threonine-protein Kinase NEK7, Human | 4500 | 0.21 | Binding ≤ 10μM |
| NEK9_HUMAN | Q8TD19 | Serine/threonine-protein Kinase NEK9, Human | 3100 | 0.22 | Binding ≤ 10μM |
| PAK1_HUMAN | Q13153 | Serine/threonine-protein Kinase PAK 1, Human | 0.57 | 0.37 | Binding ≤ 10μM |
| PAK2_HUMAN | Q13177 | Serine/threonine-protein Kinase PAK 2, Human | 1 | 0.36 | Binding ≤ 10μM |
| PAK3_HUMAN | O75914 | Serine/threonine-protein Kinase PAK 3, Human | 0.5 | 0.37 | Binding ≤ 10μM |
| PAK4_HUMAN | O96013 | Serine/threonine-protein Kinase PAK 4, Human | 6.3 | 0.33 | Binding ≤ 10μM |
| PAK6_HUMAN | Q9NQU5 | Serine/threonine-protein Kinase PAK6, Human | 0.4 | 0.38 | Binding ≤ 10μM |
| PAK7_HUMAN | Q9P286 | Serine/threonine-protein Kinase PAK7, Human | 1.2 | 0.36 | Binding ≤ 10μM |
| CDK16_HUMAN | Q00536 | Serine/threonine-protein Kinase PCTAIRE-1, Human | 24 | 0.30 | Binding ≤ 10μM |
| CDK17_HUMAN | Q00537 | Serine/threonine-protein Kinase PCTAIRE-2, Human | 96 | 0.28 | Binding ≤ 10μM |
| CDK18_HUMAN | Q07002 | Serine/threonine-protein Kinase PCTAIRE-3, Human | 270 | 0.26 | Binding ≤ 10μM |
| CDK14_HUMAN | O94921 | Serine/threonine-protein Kinase PFTAIRE-1, Human | 160 | 0.27 | Binding ≤ 10μM |
| PIM1_HUMAN | P11309 | Serine/threonine-protein Kinase PIM1, Human | 1.4 | 0.35 | Binding ≤ 10μM |
| PIM2_HUMAN | Q9P1W9 | Serine/threonine-protein Kinase PIM2, Human | 1.9 | 0.35 | Binding ≤ 10μM |
| PIM3_HUMAN | Q86V86 | Serine/threonine-protein Kinase PIM3, Human | 0.51 | 0.37 | Binding ≤ 10μM |
| PLK1_HUMAN | P53350 | Serine/threonine-protein Kinase PLK1, Human | 190 | 0.27 | Binding ≤ 10μM |
| PLK2_HUMAN | Q9NYY3 | Serine/threonine-protein Kinase PLK2, Human | 197 | 0.27 | Binding ≤ 10μM |
| PLK3_HUMAN | Q9H4B4 | Serine/threonine-protein Kinase PLK3, Human | 910 | 0.24 | Binding ≤ 10μM |
| PLK4_HUMAN | O00444 | Serine/threonine-protein Kinase PLK4, Human | 0.75 | 0.36 | Binding ≤ 10μM |
| PRKX_HUMAN | P51817 | Serine/threonine-protein Kinase PRKX, Human | 13 | 0.32 | Binding ≤ 10μM |
| RAF1_HUMAN | P04049 | Serine/threonine-protein Kinase RAF, Human | 140 | 0.27 | Binding ≤ 10μM |
| RIOK1_HUMAN | Q9BRS2 | Serine/threonine-protein Kinase RIO1, Human | 130 | 0.28 | Binding ≤ 10μM |
| RIOK3_HUMAN | O14730 | Serine/threonine-protein Kinase RIO3, Human | 76 | 0.28 | Binding ≤ 10μM |
| RIPK2_HUMAN | O43353 | Serine/threonine-protein Kinase RIPK2, Human | 5100 | 0.21 | Binding ≤ 10μM |
| SIK1_HUMAN | P57059 | Serine/threonine-protein Kinase SIK1, Human | 2.2 | 0.35 | Binding ≤ 10μM |
| SIK2_HUMAN | Q9H0K1 | Serine/threonine-protein Kinase SIK2, Human | 1.1 | 0.36 | Binding ≤ 10μM |
| SRPK1_HUMAN | Q96SB4 | Serine/threonine-protein Kinase SRPK1, Human | 5.5 | 0.33 | Binding ≤ 10μM |
| SRPK2_HUMAN | P78362 | Serine/threonine-protein Kinase SRPK2, Human | 67 | 0.29 | Binding ≤ 10μM |
| TNI3K_HUMAN | Q59H18 | Serine/threonine-protein Kinase TNNI3K, Human | 1000 | 0.24 | Binding ≤ 10μM |
| TLK1_HUMAN | Q9UKI8 | Serine/threonine-protein Kinase Tousled-like 1, Human | 27 | 0.30 | Binding ≤ 10μM |
| TLK2_HUMAN | Q86UE8 | Serine/threonine-protein Kinase Tousled-like 2, Human | 16 | 0.31 | Binding ≤ 10μM |
| WEE1_HUMAN | P30291 | Serine/threonine-protein Kinase WEE1, Human | 1600 | 0.23 | Binding ≤ 10μM |
| KIT_HUMAN | P10721 | Stem Cell Growth Factor Receptor, Human | 0.64 | 0.37 | Binding ≤ 10μM |
| TSSK1_HUMAN | Q9BXA7 | Testis-specific Serine/threonine-protein Kinase 1, Human | 24 | 0.30 | Binding ≤ 10μM |
| TGFR1_HUMAN | P36897 | TGF-beta Receptor Type I, Human | 2000 | 0.23 | Binding ≤ 10μM |
| TNIK_HUMAN | Q9UKE5 | TRAF2- And NCK-interacting Kinase, Human | 4.7 | 0.33 | Binding ≤ 10μM |
| TBA1A_RAT | P68370 | Tubulin Alpha-1 Chain, Rat | 770 | 0.24 | Binding ≤ 10μM |
| ACK1_HUMAN | Q07912 | Tyrosine Kinase Non-receptor Protein 2, Human | 16 | 0.31 | Binding ≤ 10μM |
| ABL1_HUMAN | P00519 | Tyrosine-protein Kinase ABL, Human | 100 | 0.28 | Binding ≤ 10μM |
| ABL2_HUMAN | P42684 | Tyrosine-protein Kinase ABL2, Human | 100 | 0.28 | Binding ≤ 10μM |
| BLK_MOUSE | P16277 | Tyrosine-protein Kinase BLK, Mouse | 400 | 0.26 | Binding ≤ 10μM |
| BLK_HUMAN | P51451 | Tyrosine-protein Kinase BLK, Human | 15 | 0.31 | Binding ≤ 10μM |
| BMX_HUMAN | P51813 | Tyrosine-protein Kinase BMX, Human | 170 | 0.27 | Binding ≤ 10μM |
| PTK6_HUMAN | Q13882 | Tyrosine-protein Kinase BRK, Human | 2300 | 0.23 | Binding ≤ 10μM |
| BTK_HUMAN | Q06187 | Tyrosine-protein Kinase BTK, Human | 210 | 0.27 | Binding ≤ 10μM |
| CSK_HUMAN | P41240 | Tyrosine-protein Kinase CSK, Human | 330 | 0.26 | Binding ≤ 10μM |
| FER_HUMAN | P16591 | Tyrosine-protein Kinase FER, Human | 24 | 0.30 | Binding ≤ 10μM |
| FES_HUMAN | P07332 | Tyrosine-protein Kinase FES, Human | 23 | 0.31 | Binding ≤ 10μM |
| FGR_HUMAN | P09769 | Tyrosine-protein Kinase FGR, Human | 17 | 0.31 | Binding ≤ 10μM |
| FRK_HUMAN | P42685 | Tyrosine-protein Kinase FRK, Human | 260 | 0.26 | Binding ≤ 10μM |
| FYN_HUMAN | P06241 | Tyrosine-protein Kinase FYN, Human | 15 | 0.31 | Binding ≤ 10μM |
| HCK_HUMAN | P08631 | Tyrosine-protein Kinase HCK, Human | 12 | 0.32 | Binding ≤ 10μM |
| ITK_HUMAN | Q08881 | Tyrosine-protein Kinase ITK/TSK, Human | 19 | 0.31 | Binding ≤ 10μM |
| JAK2_HUMAN | O60674 | Tyrosine-protein Kinase JAK2, Human | 11 | 0.32 | Binding ≤ 10μM |
| JAK3_HUMAN | P52333 | Tyrosine-protein Kinase JAK3, Human | 0.15 | 0.39 | Binding ≤ 10μM |
| LCK_HUMAN | P06239 | Tyrosine-protein Kinase LCK, Human | 1.5 | 0.35 | Binding ≤ 10μM |
| LYN_HUMAN | P07948 | Tyrosine-protein Kinase Lyn, Human | 0.49 | 0.37 | Binding ≤ 10μM |
| FLT3_HUMAN | P36888 | Tyrosine-protein Kinase Receptor FLT3, Human | 1 | 0.36 | Binding ≤ 10μM |
| RET_HUMAN | P07949 | Tyrosine-protein Kinase Receptor RET, Human | 0.46 | 0.37 | Binding ≤ 10μM |
| TIE1_HUMAN | P35590 | Tyrosine-protein Kinase Receptor Tie-1, Human | 65 | 0.29 | Binding ≤ 10μM |
| TYRO3_HUMAN | Q06418 | Tyrosine-protein Kinase Receptor TYRO3, Human | 280 | 0.26 | Binding ≤ 10μM |
| UFO_HUMAN | P30530 | Tyrosine-protein Kinase Receptor UFO, Human | 6.8 | 0.33 | Binding ≤ 10μM |
| SRC_HUMAN | P12931 | Tyrosine-protein Kinase SRC, Human | 1 | 0.36 | Binding ≤ 10μM |
| SRMS_HUMAN | Q9H3Y6 | Tyrosine-protein Kinase Srms, Human | 740 | 0.25 | Binding ≤ 10μM |
| KSYK_HUMAN | P43405 | Tyrosine-protein Kinase SYK, Human | 0.1 | 0.40 | Binding ≤ 10μM |
| TEC_HUMAN | P42680 | Tyrosine-protein Kinase TEC, Human | 1300 | 0.24 | Binding ≤ 10μM |
| TIE2_HUMAN | Q02763 | Tyrosine-protein Kinase TIE-2, Human | 140 | 0.27 | Binding ≤ 10μM |
| TXK_HUMAN | P42681 | Tyrosine-protein Kinase TXK, Human | 230 | 0.27 | Binding ≤ 10μM |
| TYK2_HUMAN | P29597 | Tyrosine-protein Kinase TYK2, Human | 56 | 0.29 | Binding ≤ 10μM |
| YES_HUMAN | P07947 | Tyrosine-protein Kinase YES, Human | 49 | 0.29 | Binding ≤ 10μM |
| ZAP70_HUMAN | P43403 | Tyrosine-protein Kinase ZAP-70, Human | 44 | 0.29 | Binding ≤ 10μM |
| ULK3_MOUSE | Q3U3Q1 | ULK3 Kinase, Mouse | 3 | 0.34 | Binding ≤ 10μM |
| VGFR1_MOUSE | P35969 | Vascular Endothelial Growth Factor Receptor 1, Mouse | 14 | 0.31 | Binding ≤ 10μM |
| VGFR1_HUMAN | P17948 | Vascular Endothelial Growth Factor Receptor 1, Human | 150 | 0.27 | Binding ≤ 10μM |
| VGFR2_HUMAN | P35968 | Vascular Endothelial Growth Factor Receptor 2, Human | 1.2 | 0.36 | Binding ≤ 10μM |
| VGFR2_MOUSE | P35918 | Vascular Endothelial Growth Factor Receptor 2, Mouse | 14 | 0.31 | Binding ≤ 10μM |
| VGFR3_MOUSE | P35917 | Vascular Endothelial Growth Factor Receptor 3, Mouse | 14 | 0.31 | Binding ≤ 10μM |
| VGFR3_HUMAN | P35916 | Vascular Endothelial Growth Factor Receptor 3, Human | 1.9 | 0.35 | Binding ≤ 10μM |
| Z50512 | Z50512 | Cavia Porcellus | 25 | 0.30 | Functional ≤ 10μM |
| Z80120 | Z80120 | DLD-1 (Colon Adenocarcinoma Cells) | 9 | 0.32 | Functional ≤ 10μM |
| Z80928 | Z80928 | HCT-116 (Colon Carcinoma Cells) | 6 | 0.33 | Functional ≤ 10μM |
| Z80936 | Z80936 | HEK293 (Embryonic Kidney Fibroblasts) | 77 | 0.28 | Functional ≤ 10μM |
| Z81247 | Z81247 | HeLa (Cervical Adenocarcinoma Cells) | 0.1 | 0.40 | Functional ≤ 10μM |
| Z80166 | Z80166 | HT-29 (Colon Adenocarcinoma Cells) | 2 | 0.35 | Functional ≤ 10μM |
| Z81057 | Z81057 | HUVEC (Umbilical Vein Endothelial Cells) | 4 | 0.34 | Functional ≤ 10μM |
| Z81072 | Z81072 | Jurkat (Acute Leukemic T-cells) | 311 | 0.26 | Functional ≤ 10μM |
| Z80211 | Z80211 | LoVo (Colon Adenocarcinoma Cells) | 1 | 0.36 | Functional ≤ 10μM |
| Z80224 | Z80224 | MCF7 (Breast Carcinoma Cells) | 50 | 0.29 | Functional ≤ 10μM |
| Z80800 | Z80800 | MIA PaCa-2 (Pancreatic Carcinoma Cells) | 370 | 0.26 | Functional ≤ 10μM |
| Z100081 | Z100081 | PBMC (Peripheral Blood Mononuclear Cells) | 16 | 0.31 | Functional ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 0.1 | 0.40 | Functional ≤ 10μM |
| KPCB_HUMAN | P05771 | Protein Kinase C Beta, Human | 77 | 0.28 | Functional ≤ 10μM |
| AKT1_HUMAN | P31749 | Serine/threonine-protein Kinase AKT, Human | 290 | 0.26 | Functional ≤ 10μM |
| Z100201 | Z100201 | Splenocytes (Spleen Cells) | 400 | 0.26 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Acetylcholine regulates insulin secretion | |
| Activated point mutants of FGFR2 | |
| activated TAK1 mediates p38 MAPK activation | |
| Activation of ATR in response to replication stress | |
| Activation of BAD and translocation to mitochondria | |
| Activation of BIM and translocation to mitochondria | |
| Activation of BMF and translocation to mitochondria | |
| Activation of CaMK IV | |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | |
| Activation of NF-kappaB in B cells | |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | |
| Activation of PKB | |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | |
| Activation of Rac | |
| Activation of the AP-1 family of transcription factors | |
| Activation of the pre-replicative complex | |
| ADP signalling through P2Y purinoceptor 1 | |
| Advanced glycosylation endproduct receptor signaling | |
| AKT phosphorylates targets in the cytosol | |
| AKT phosphorylates targets in the nucleus | |
| AKT-mediated inactivation of FOXO1A | |
| AMPK inhibits chREBP transcriptional activation activity | |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messenge | |
| APC truncation mutants have impaired AXIN binding | |
| APC/C:Cdc20 mediated degradation of Cyclin B | |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins | |
| Apoptotic cleavage of cellular proteins | |
| Apoptotic execution phase | |
| ARMS-mediated activation | |
| AXIN missense mutants destabilize the destruction complex | |
| Beta-catenin phosphorylation cascade | |
| betaKlotho-mediated ligand binding | |
| Butyrate Response Factor 1 (BRF1) destabilizes mRNA | |
| Ca2+ pathway | |
| Calmodulin induced events | |
| CaMK IV-mediated phosphorylation of CREB | |
| CD28 co-stimulation | |
| CD28 dependent PI3K/Akt signaling | |
| CD28 dependent Vav1 pathway | |
| CDK-mediated phosphorylation and removal of Cdc6 | |
| CDO in myogenesis | |
| Cell surface interactions at the vascular wall | |
| cGMP effects | |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |
| Circadian Clock | |
| Condensation of Prometaphase Chromosomes | |
| Condensation of Prophase Chromosomes | |
| Constitutive PI3K/AKT Signaling in Cancer | |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |
| CREB phosphorylation | |
| CREB phosphorylation through the activation of Adenylate Cyclase | |
| CREB phosphorylation through the activation of CaMKII | |
| CREB phosphorylation through the activation of CaMKK | |
| CREB phosphorylation through the activation of Ras | |
| CRMPs in Sema3A signaling | |
| CTLA4 inhibitory signaling | |
| Cyclin A/B1 associated events during G2/M transition | |
| Cyclin A:Cdk2-associated events at S phase entry | |
| Cyclin B2 mediated events | |
| Cyclin D associated events in G1 | |
| Cyclin E associated events during G1/S transition | |
| Cytosolic tRNA aminoacylation | |
| DAG and IP3 signaling | |
| DAP12 signaling | |
| DARPP-32 events | |
| DCC mediated attractive signaling | |
| deactivation of the beta-catenin transactivating complex | |
| Degradation of beta-catenin by the destruction complex | |
| Depolymerisation of the Nuclear Lamina | |
| disassembly of the destruction complex and recruitment of AXIN to the membrane | |
| Disinhibition of SNARE formation | |
| DNA Damage/Telomere Stress Induced Senescence | |
| Downregulation of ERBB2:ERBB3 signaling | |
| Downregulation of TGF-beta receptor signaling | |
| Downstream signal transduction | |
| Downstream TCR signaling | |
| DSCAM interactions | |
| Dual incision reaction in GG-NER | |
| Dual incision reaction in TC-NER | |
| E2F mediated regulation of DNA replication | |
| E2F-enabled inhibition of pre-replication complex formation | |
| ECM proteoglycans | |
| Effects of PIP2 hydrolysis | |
| EGFR downregulation | |
| EGFR interacts with phospholipase C-gamma | |
| EGFR Transactivation by Gastrin | |
| eNOS activation | |
| EPH-ephrin mediated repulsion of cells | |
| EPH-Ephrin signaling | |
| EPHA-mediated growth cone collapse | |
| EPHB-mediated forward signaling | |
| Ephrin signaling | |
| ERK/MAPK targets | |
| ERK1 activation | |
| ERK2 activation | |
| ERKs are inactivated | |
| Factors involved in megakaryocyte development and platelet production | |
| Fc epsilon receptor (FCERI) signaling | |
| FCERI mediated Ca+2 mobilization | |
| FCERI mediated MAPK activation | |
| FCERI mediated NF-kB activation | |
| FCGR activation | |
| FGFR4 ligand binding and activation | |
| Formation of HIV elongation complex in the absence of HIV Tat | |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | |
| Formation of incision complex in GG-NER | |
| Formation of RNA Pol II elongation complex | |
| Formation of the Early Elongation Complex | |
| Formation of the HIV-1 Early Elongation Complex | |
| Formation of transcription-coupled NER (TC-NER) repair complex | |
| Formation of tubulin folding intermediates by CCT/TriC | |
| Frs2-mediated activation | |
| FRS2-mediated cascade | |
| G alpha (12/13) signalling events | |
| G alpha (z) signalling events | |
| G beta:gamma signalling through PI3Kgamma | |
| G0 and Early G1 | |
| G1/S-Specific Transcription | |
| G2 Phase | |
| G2/M DNA damage checkpoint | |
| G2/M DNA replication checkpoint | |
| GAB1 signalosome | |
| Gap junction assembly | |
| Gastrin-CREB signalling pathway via PKC and MAPK | |
| Generation of second messenger molecules | |
| Generic Transcription Pathway | |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | |
| Gluconeogenesis | |
| Glycogen breakdown (glycogenolysis) | |
| Golgi Associated Vesicle Biogenesis | |
| Golgi Cisternae Pericentriolar Stack Reorganization | |
| GP1b-IX-V activation signalling | |
| GPVI-mediated activation cascade | |
| GRB2 events in EGFR signaling | |
| GRB2 events in ERBB2 signaling | |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | |
| Growth hormone receptor signaling | |
| HIV elongation arrest and recovery | |
| HIV Transcription Initiation | |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |
| HSF1-dependent transactivation | |
| HuR stabilizes mRNA | |
| IKK complex recruitment mediated by RIP1 | |
| Import of palmitoyl-CoA into the mitochondrial matrix | |
| Inactivation, recovery and regulation of the phototransduction cascade | |
| Inhibition of PKR | |
| Inhibition of TSC complex formation by PKB | |
| Insulin receptor recycling | |
| Integrin alphaIIb beta3 signaling | |
| Integrin cell surface interactions | |
| Interactions of Tat with host cellular proteins | |
| Interferon alpha/beta signaling | |
| Interferon gamma signaling | |
| Interleukin receptor SHC signaling | |
| Interleukin-1 signaling | |
| Interleukin-2 signaling | |
| Interleukin-3, 5 and GM-CSF signaling | |
| Interleukin-6 signaling | |
| Interleukin-7 signaling | |
| IRAK1 recruits IKK complex | |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | |
| IRAK2 mediated activation of TAK1 complex | |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | |
| IRS activation | |
| IRS-related events triggered by IGF1R | |
| ISG15 antiviral mechanism | |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human | |
| Kinesins | |
| KSRP destabilizes mRNA | |
| L1CAM interactions | |
| Loss of Nlp from mitotic centrosomes | |
| Loss of proteins required for interphase microtubule organization from the ce | |
| MASTL Facilitates Mitotic Progression | |
| Meiotic recombination | |
| MEK activation | |
| MHC class II antigen presentation | |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | |
| misspliced GSK3beta mutants stabilize beta-catenin | |
| Mitochondrial tRNA aminoacylation | |
| Mitotic Metaphase/Anaphase Transition | |
| Mitotic Prometaphase | |
| Mitotic Telophase/Cytokinesis | |
| mRNA Capping | |
| MyD88 cascade initiated on plasma membrane | |
| MyD88 dependent cascade initiated on endosome | |
| MyD88:Mal cascade initiated on plasma membrane | |
| NCAM signaling for neurite out-growth | |
| Nef and signal transduction | |
| Nef Mediated CD4 Down-regulation | |
| Negative regulation of FGFR signaling | |
| Negative regulation of the PI3K/AKT network | |
| Negative regulators of RIG-I/MDA5 signaling | |
| Nephrin interactions | |
| Netrin mediated repulsion signals | |
| Netrin-1 signaling | |
| Neurophilin interactions with VEGF and VEGFR | |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | |
| NF-kB is activated and signals survival | |
| NGF-independant TRKA activation | |
| NOD1/2 Signaling Pathway | |
| Non-integrin membrane-ECM interactions | |
| NoRC negatively regulates rRNA expression | |
| NOTCH1 Intracellular Domain Regulates Transcription | |
| NRAGE signals death through JNK | |
| NRIF signals cell death from the nucleus | |
| Nuclear Pore Complex (NPC) Disassembly | |
| Oncogene Induced Senescence | |
| Orc1 removal from chromatin | |
| Oxidative Stress Induced Senescence | |
| p130Cas linkage to MAPK signaling for integrins | |
| p38MAPK events | |
| p53-Dependent G1 DNA Damage Response | |
| p75NTR recruits signalling complexes | |
| Pausing and recovery of HIV elongation | |
| Pausing and recovery of Tat-mediated HIV elongation | |
| PD-1 signaling | |
| PDE3B signalling | |
| PECAM1 interactions | |
| phospho-PLA2 pathway | |
| Phospholipase C-mediated cascade | |
| Phosphorylation of CD3 and TCR zeta chains | |
| Phosphorylation of Emi1 | |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 | |
| Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 com | |
| Phosphorylation of the APC/C | |
| PI-3K cascade | |
| PI3K Cascade | |
| PI3K events in ERBB2 signaling | |
| PI3K/AKT activation | |
| PIP3 activates AKT signaling | |
| PKA activation | |
| PKA activation in glucagon signalling | |
| PKA-mediated phosphorylation of CREB | |
| PKA-mediated phosphorylation of key metabolic factors | |
| Platelet Adhesion to exposed collagen | |
| Platelet sensitization by LDL | |
| PLC-gamma1 signalling | |
| PLCG1 events in ERBB2 signaling | |
| Polo-like kinase mediated events | |
| Post-chaperonin tubulin folding pathway | |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | |
| PPARA activates gene expression | |
| Prefoldin mediated transfer of substrate to CCT/TriC | |
| Prolactin receptor signaling | |
| RAF activation | |
| RAF phosphorylates MEK | |
| Rap1 signalling | |
| Ras activation uopn Ca2+ infux through NMDA receptor | |
| Recruitment of mitotic centrosome proteins and complexes | |
| Recruitment of NuMA to mitotic centrosomes | |
| Recycling pathway of L1 | |
| Regulation of actin dynamics for phagocytic cup formation | |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | |
| Regulation of AMPK activity via LKB1 | |
| Regulation of APC/C activators between G1/S and early anaphase | |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex componen | |
| Regulation of HSF1-mediated heat shock response | |
| Regulation of IFNA signaling | |
| Regulation of IFNG signaling | |
| Regulation of insulin secretion | |
| Regulation of KIT signaling | |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | |
| Regulation of PLK1 Activity at G2/M Transition | |
| Regulation of Rheb GTPase activity by AMPK | |
| Regulation of signaling by CBL | |
| Regulation of signaling by NODAL | |
| Resolution of Sister Chromatid Cohesion | |
| Response to elevated platelet cytosolic Ca2+ | |
| Retrograde neurotrophin signalling | |
| RIP-mediated NFkB activation via ZBP1 | |
| RMTs methylate histone arginines | |
| RNA Pol II CTD phosphorylation and interaction with CE | |
| RNA Polymerase I Chain Elongation | |
| RNA Polymerase I Promoter Escape | |
| RNA Polymerase I Promoter Opening | |
| RNA Polymerase I Transcription Initiation | |
| RNA Polymerase I Transcription Termination | |
| RNA Polymerase II HIV Promoter Escape | |
| RNA Polymerase II Pre-transcription Events | |
| RNA Polymerase II Promoter Escape | |
| RNA Polymerase II Transcription Elongation | |
| RNA Polymerase II Transcription Initiation | |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | |
| Role of Abl in Robo-Slit signaling | |
| Role of DCC in regulating apoptosis | |
| Role of LAT2/NTAL/LAB on calcium mobilization | |
| Role of phospholipids in phagocytosis | |
| RSK activation | |
| S33 mutants of beta-catenin aren't phosphorylated | |
| S37 mutants of beta-catenin aren't phosphorylated | |
| S45 mutants of beta-catenin aren't phosphorylated | |
| S6K1 signalling | |
| S6K1-mediated signalling | |
| SCF(Skp2)-mediated degradation of p27/p21 | |
| Sema3A PAK dependent Axon repulsion | |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | |
| Sema4D induced cell migration and growth-cone collapse | |
| Sema4D mediated inhibition of cell attachment and migration | |
| Senescence-Associated Secretory Phenotype (SASP) | |
| Separation of Sister Chromatids | |
| SHC activation | |
| SHC-mediated cascade | |
| SHC-related events triggered by IGF1R | |
| SHC1 events in EGFR signaling | |
| SHC1 events in ERBB2 signaling | |
| Signal attenuation | |
| Signal regulatory protein (SIRP) family interactions | |
| Signal transduction by L1 | |
| Signaling by activated point mutants of FGFR1 | |
| Signaling by activated point mutants of FGFR3 | |
| Signaling by Activin | |
| Signaling by BMP | |
| Signaling by constitutively active EGFR | |
| Signaling by EGFR | |
| Signaling by ERBB2 | |
| Signaling by ERBB4 | |
| Signaling by FGFR | |
| Signaling by FGFR mutants | |
| Signaling by FGFR2 amplification mutants | |
| Signaling by FGFR3 mutants | |
| Signaling by FGFR4 mutants | |
| Signaling by Hippo | |
| Signaling by Insulin receptor | |
| Signaling by Leptin | |
| Signaling by NODAL | |
| Signaling by PDGF | |
| Signaling by SCF-KIT | |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | |
| Signalling to ERK5 | |
| Signalling to p38 via RIT and RIN | |
| Signalling to RAS | |
| Signalling to STAT3 | |
| SMAD2/3 MH2 Domain Mutants in Cancer | |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | |
| Smooth Muscle Contraction | |
| Sphingolipid de novo biosynthesis | |
| Spry regulation of FGF signaling | |
| Stimulation of the cell death response by PAK-2p34 | |
| Stimuli-sensing channels | |
| Syndecan interactions | |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | |
| Synthesis of PIPs at the plasma membrane | |
| t(4;14) translocations of FGFR3 | |
| T41 mutants of beta-catenin aren't phosphorylated | |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | |
| Tat-mediated elongation of the HIV-1 transcript | |
| Tat-mediated HIV elongation arrest and recovery | |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | |
| TGF-beta receptor signaling activates SMADs | |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | |
| TGFBR1 KD Mutants in Cancer | |
| TGFBR1 LBD Mutants in Cancer | |
| TGFBR2 Kinase Domain Mutants in Cancer | |
| Thrombin signalling through proteinase activated receptors (PARs) | |
| Tie2 Signaling | |
| Tight junction interactions | |
| TRAF3-dependent IRF activation pathway | |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | |
| TRAF6 mediated induction of TAK1 complex | |
| TRAF6 mediated IRF7 activation | |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | |
| TRAF6 mediated NF-kB activation | |
| Trafficking of AMPA receptors | |
| Trafficking of GluR2-containing AMPA receptors | |
| Transcription of the HIV genome | |
| Transcriptional activation of mitochondrial biogenesis | |
| Transcriptional regulation of white adipocyte differentiation | |
| Translocation of GLUT4 to the plasma membrane | |
| Translocation of ZAP-70 to Immunological synapse | |
| Tristetraprolin (TTP) destabilizes mRNA | |
| TRKA activation by NGF | |
| truncations of AMER1 destabilize the destruction complex | |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |
| Ubiquitin-dependent degradation of Cyclin D1 | |
| Unblocking of NMDA receptor, glutamate binding and activation | |
| Uptake and function of anthrax toxins | |
| Vasopressin regulates renal water homeostasis via Aquaporins | |
| VEGF binds to VEGFR leading to receptor dimerization | |
| VEGFA-VEGFR2 Pathway | |
| VEGFR2 mediated cell proliferation | |
| VEGFR2 mediated vascular permeability | |
| WNT mediated activation of DVL | |
| WNT5A-dependent internalization of FZD4 | |
| XBP1(S) activates chaperone genes |
