UCSF

Disintegrin And Metalloproteinase Domain-containing Protein 8, Human (1 Compounds)

Swissprot:
ADAM8_HUMAN
Stitch:
ADAM8_HUMAN
UniProt:
P78325
ChEMBL:
CHEMBL5665
Reactome:
REACT_118572
PDB:
ADAM8

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 0
Binding ≤ 1μM 1 0 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_118572 Degradation of the extracellular matrix Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 1
MMP12_HUMAN P39900 CHEMBL4393 Matrix Metalloproteinase 12, Human 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 1
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 1
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADAM9_HUMAN Q13443 CHEMBL5982 ADAM9, Human 66 1 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 1
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 1
ADA33_HUMAN Q9BZ11 CHEMBL6121 Disintegrin And Metalloproteinase Domain-containing Protein 33, Human 1
MMP12_HUMAN P39900 CHEMBL4393 Matrix Metalloproteinase 12, Human 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 1
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 1
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1