UCSF

Cyclooxygenase-1, Sheep (198 Compounds)

Swissprot:
PGH1_SHEEP
Stitch:
PGH1_SHEEP
UniProt:
P05979
ChEMBL:
CHEMBL2949
PDB:
1CQE (DOCK)
1DIY (DOCK)
1DJJ (DOCK)
1EBV (DOCK)
1EQG (DOCK)
1EQH (DOCK)
1FE2 (DOCK)
1HT5 (DOCK)
1HT8 (DOCK)
1IGX (DOCK)
1IGZ (DOCK)
1PGE (DOCK)
1PGF (DOCK)
1PGG (DOCK)
1PRH (DOCK)
1PTH (DOCK)
1Q4G (DOCK)
1U67 (DOCK)
2AYL (DOCK)
2OYE (DOCK)
2OYU (DOCK)
3KK6 (DOCK)
3N8V (DOCK)
3N8W (DOCK)
3N8X (DOCK)
3N8Y (DOCK)
3N8Z (DOCK)
PTGS1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 198 36 21 23
Binding ≤ 1μM 89 14 9 14

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 100 16 12 12
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 969 95 65 44
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 37 7 3 3
PGH1_RABIT O97554 CHEMBL3334 Cyclooxygenase-1, Rabit 9 1 1 1
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 252 34 20 18
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 284 34 17 15

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
PGH1-1-E Cyclooxygenase-1 (cluster #1 Of 6), Eukaryotic 834 44 17 19
PGH1-2-E Cyclooxygenase-1 (cluster #2 Of 6), Eukaryotic 351 70 53 38
PGH1-3-E Cyclooxygenase-1 (cluster #3 Of 6), Eukaryotic 70 17 5 3
PGH1-4-E Cyclooxygenase-1 (cluster #4 Of 6), Eukaryotic 47 7 6 3
PGH1-5-E Cyclooxygenase-1 (cluster #5 Of 6), Eukaryotic 108 5 6 0
PGH1-6-E Cyclooxygenase-1 (cluster #6 Of 6), Eukaryotic 61 7 6 7
Uniprot Swissprot Chembl Description Number Shared
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 79
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 74
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 30
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 24
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 12
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 11
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 8
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 8
O49150_SOLTU O49150 CHEMBL3317 5-lipoxygenase, Soltu 8
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 6
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 6
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 6
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 6
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 6
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 6
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 5
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 5
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 5
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 5
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 5
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 4
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 4
PGH2_BOVIN O62698 CHEMBL3331 Cyclooxygenase-2, Bovin 4
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 3
IL8_HUMAN P10145 CHEMBL2157 Interleukin-8, Human 3
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 2
ALBU_BOVIN P02769 CHEMBL3728 Serum Albumin, Bovin 2
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 2
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 2
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 2
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 2
S22A6_MOUSE Q8VC69 CHEMBL5653 Solute Carrier Family 22 Member 6, Mouse 2
S22AK_MOUSE Q80UJ1 CHEMBL5269 Solute Carrier Family 22 Member 20, Mouse 2
AHR_RABIT O02747 CHEMBL4725 Aryl Hydrocarbon Receptor, Rabit 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
B5SU02_9CNID B5SU02 CHEMBL1075028 Alpha Carbonic Anhydrase, 9cnid 1
C0IX24_9CNID C0IX24 CHEMBL1649055 Carbonic Anhydrase, 9cnid 1
CAH4_BOVIN Q95323 CHEMBL281 Carbonic Anhydrase IV, Bovin 1
CAH_METTE P40881 CHEMBL3932 Carbonic Anhydrase, Mette 1
CAN_YEAST P53615 CHEMBL5931 Carbonic Anhydrase, Yeast 1
CISD1_HUMAN Q9NZ45 CHEMBL1795168 CDGSH Iron-sulfur Domain-containing Protein 1, Human 1
CLTR2_HUMAN Q9NS75 CHEMBL4330 Cysteinyl Leukotriene Receptor 2, Human 1
COX2_SHEEP O78750 CHEMBL1250404 Cytochrome C Oxidase Subunit 2, Sheep 1
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 1
CYNT_MYCTU O53573 CHEMBL6068 Carbonic Anhydrase, Myctu 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
LIPS_RAT P15304 CHEMBL5582 Hormone-sensitive Lipase, Rat 1
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
NQO2_HUMAN P16083 CHEMBL3959 Quinone Reductase 2, Human 1
PTGDS_MOUSE O09114 CHEMBL4334 Prostaglandin-H2 D-isomerase, Mouse 1
Q2PCB5_DICLA Q2PCB5 CHEMBL1795125 Carbonic Anhydrase, Dicla 1
Q5AJ71_CANAL Q5AJ71 CHEMBL5337 Carbonic Anhydrase, Canal 1
Q8HZR1_CANFA Q8HZR1 CHEMBL4133 Cyclooxygenase-1, Canine 1
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 1