UCSF

AKOS (make-on-demand)

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

ADME/T 10μM Targets with Highest Number of Available Compounds (36 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2DQ_RAT P10634 CHEMBL2483 Cytochrome P450 2D2 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_HUMAN Q06278 CHEMBL3257 Aldehyde oxidase 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
S15A2_HUMAN Q16348 CHEMBL1743125 Solute carrier family 15 member 2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80409 Z80409 CHEMBL614385 R2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80583 Z80583 CHEMBL391 Vero (Kidney cells) 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_RABIT P80456 CHEMBL1641356 Aldehyde oxidase 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2B6_HUMAN P20813 CHEMBL4729 Cytochrome P450 2B6 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81135 Z81135 CHEMBL614793 L6 (Skeletal muscle myoblast cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_MACFA Q5FB27 CHEMBL1641357 Aldehyde oxidase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_MOUSE O54754 CHEMBL1641354 Aldehyde oxidase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_RAT Q9Z0U5 CHEMBL1641355 Aldehyde oxidase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2A6_HUMAN P11509 CHEMBL5282 Cytochrome P450 2A6 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2B1_RAT P00176 CHEMBL3335 Cytochrome P450 2B1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2B4_RABIT P00178 CHEMBL1743542 Cytochrome P450 2B4 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2C8_HUMAN P10632 CHEMBL3721 Cytochrome P450 2C8 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2DI_RAT Q64680 CHEMBL4982 Cytochrome P450 2D18 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2E1_HUMAN P05181 CHEMBL5281 Cytochrome P450 2E1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80192 Z80192 CHEMBL614709 KM12 (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80253 Z80253 CHEMBL614342 MEF (Embryonic fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80384 Z80384 CHEMBL614233 PBL (Peripheral blood lymphocytes) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80390 Z80390 CHEMBL390 PC-3 (Prostate carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80874 Z80874 CHEMBL393 CEM (T-cell leukemia) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80897 Z80897 CHEMBL614806 H9 (T-lymphoid cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80901 Z80901 CHEMBL614392 HaCaT (Keratinocytes) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80954 Z80954 CHEMBL614071 HFF (Foreskin fibroblasts) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81115 Z81115 CHEMBL398 KB (Squamous cell carcinoma) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate carcinoma) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase