UCSF

PKChem

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 10μM Targets with Highest Number of Available Compounds (15 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
GRM5_RAT P31424 CHEMBL2564 Metabotropic glutamate receptor 5 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_MOUSE P37238 CHEMBL2459 Peroxisome proliferator-activated receptor gamma 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic glutamate receptor 5 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
TOP3_BACSU P96583 CHEMBL4320 DNA topoisomerase III 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPO3_BACSU P13267 CHEMBL3897 DNA polymerase III 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal growth factor receptor erbB1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor protein-tyrosine kinase erbB-2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LUCI_PHOPE Q27757 CHEMBL5150 Luciferin 4-monooxygenase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LUCI_PHOPY P08659 CHEMBL5567 Luciferin 4-monooxygenase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_MOUSE P42337 CHEMBL2499 PI3-kinase p110-alpha subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase p110-beta subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase p110-delta subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier protein reductase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SHH_MOUSE Q62226 CHEMBL5387 Sonic hedgehog protein 1 Annotations Catalogs SMILES SDF Mol2 Flexibase