UCSF
Image of 2,10-dihydropyrazolo[3,4-b][1,4]benzodiazepine

Identity 99% 90% 80% 70% Substructure

2,10-dihydropyrazolo[3,4-b][1,4]benzodiazepine

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
3 1 14 10 4 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 0 0 22 0 0 2012-04-17

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80427 Z80427 CHEMBL614879 RKO (Colon Carcinoma) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase