| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 4th, 2005 | 16 | No |
Popular Name: Furazolidone Furazolidone
2-Furanmethanimine, 5-nitro-N-(2-oxo-3-oxazolidinyl)-
2-Oxazolidinone, 3-(((5-nitro-2-furanyl)methylene)amino)-
2-Oxazolidinone, 3-((5-nitrofurfurylidene)amino)-
2-Oxazolidinone, 3-((5-nitrofurfurylidine)amino)-
2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
3-(((5-Nitro-2-furanyl)methylene)amino)-2-oxazolidinone
3-((5-Nitrofurfurylidene)amino)-2-oxazolidinone
3-((5-Nitrofurfurylidene)amino)-2-oxazolidone
3-((5-Nitrofurylidene)amino)-2-oxazolidone
3-(5'-Nitrofurfuralamino)-2-oxazolidone
3-(5-Nitrofurfurylideneamino)-2-oxazolidinone
3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone
3-[(5-Nitrofurfurylidene)amino]-2-oxazolidone
3-[(5-Nitrofurylidene)amino]-2-oxazolidone
3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone
3-{[(5-Nitro-2-furanyl)methylene]amino}-2-oxazolidinone
3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one
3-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
3-{[(E)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
3-{[1-(5-Nitro-furan-2-yl)-meth-(E)-ylidene]-amino}-oxazolidin-2-one
5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine
67-45-8; D00830; Furazolidone (USP/INN); Furoxone (TN)
67-45-8; Furazolidone; Prestwick_1067
Furazolidone, Antibiotic for Culture Media Use Only
Furox Aerosol Powder (Veterinary)
InChI=1/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5
N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.83 | 2.48 | -32.24 | 0 | 8 | 0 | 101 | 225.16 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| biological_use | . | IBScreen Bioactives |
| Melting_Point | 254-256? dec. | Alfa-Aesar |
| Melting_Point | 254-256° dec. | Alfa-Aesar |
| ALOGPS_SOLUBILITY | 3.64e-01 g/l | DrugBank-approved |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| biological_use | Activity against: Escherichia coli | IBScreen Bioactives |
| therap | antibacterial | MicroSource Spectrum |
| Therapy | antimicrobial | SMDC Iconix |
| biological_use | Antiseptic, antiprotozoal and antibacterial agent | IBScreen Bioactives |
| biological_use | Enterobacter aerogenes | IBScreen Bioactives |
| biological_use | Giardia lamblia. | IBScreen Bioactives |
| mechanism | Interferes with several bacterial Enzyme systems | IBScreen Bioactives |
| biological_use | Proteus | IBScreen Bioactives |
| biological_use | Staphylococcus | IBScreen Bioactives |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50466-7-O | Trypanosoma Cruzi (cluster #7 Of 8), Other | Other | 400 | 0.56 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50466 | Z50466 | Trypanosoma Cruzi | 400 | 0.56 | Functional ≤ 10μM |
