Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
0.54 |
2.94 |
-10.71 |
2 |
4 |
0 |
66 |
190.202 |
0 |
↓
|
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
GRID1-1-E |
Glutamate Receptor Delta-1 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMD3A-5-E |
Glutamate [NMDA] Receptor Subunit 3A (cluster #5 Of 6), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMD3B-5-E |
Glutamate [NMDA] Receptor Subunit 3B (cluster #5 Of 6), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMDE1-3-E |
Glutamate [NMDA] Receptor Subunit Epsilon 1 (cluster #3 Of 5), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMDE2-3-E |
Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #3 Of 5), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMDE3-2-E |
Glutamate [NMDA] Receptor Subunit Epsilon 3 (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMDE4-5-E |
Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #5 Of 6), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
NMDZ1-3-E |
Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #3 Of 6), Eukaryotic |
Eukaryotes |
2100 |
0.57 |
Binding ≤ 10μM
|
Z104302-4-O |
Glutamate NMDA Receptor (cluster #4 Of 7), Other |
Other |
2100 |
0.57 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
CREB phosphorylation through the activation of CaMKII |
|
EPHB-mediated forward signaling |
|
Ras activation uopn Ca2+ infux through NMDA receptor |
|
Unblocking of NMDA receptor, glutamate binding and activation |
|
No pre-computed analogs available. Try a structural similarity search.