| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 23 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.40 | 12.45 | -50.87 | 0 | 2 | -1 | 40 | 301.365 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R2-1-E | Prostanoid EP2 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 8100 | 0.31 | Binding ≤ 10μM |
| PE2R3-3-E | Prostanoid EP3 Receptor (cluster #3 Of 3), Eukaryotic | Eukaryotes | 750 | 0.37 | Binding ≤ 10μM |
| PE2R4-1-E | Prostanoid EP4 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6000 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R3_HUMAN | P43115 | Prostanoid EP3 Receptor, Human | 750 | 0.37 | Binding ≤ 1μM |
| PE2R2_HUMAN | P43116 | Prostanoid EP2 Receptor, Human | 8100 | 0.31 | Binding ≤ 10μM |
| PE2R3_HUMAN | P43115 | Prostanoid EP3 Receptor, Human | 750 | 0.37 | Binding ≤ 10μM |
| PE2R4_HUMAN | P35408 | Prostanoid EP4 Receptor, Human | 6000 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
