Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.67	7.05	-80.03	3	9	0	105	487.586	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.67	6.77	-57.51	2	9	-1	103	486.578	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
MMP1-1-E	Matrix Metalloproteinase-1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1800	0.24	Binding ≤ 10μM
MMP3-1-E	Matrix Metalloproteinase 3 (cluster #1 Of 3), Eukaryotic	Eukaryotes	270	0.28	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
MMP3_HUMAN	P08254	Matrix Metalloproteinase 3, Human	270	0.28	Binding ≤ 1μM
MMP3_HUMAN	P08254	Matrix Metalloproteinase 3, Human	270	0.28	Binding ≤ 10μM
MMP1_HUMAN	P03956	Matrix Metalloproteinase-1, Human	1800	0.24	Binding ≤ 10μM

Description	Species
Activation of Matrix Metalloproteinases	Homo sapiens (MMP1_HUMAN)
Assembly of collagen fibrils and other multimeric structures	Homo sapiens (MMP3_HUMAN)
Basigin interactions	Homo sapiens (MMP1_HUMAN)
Collagen degradation	Homo sapiens (MMP1_HUMAN)
Degradation of the extracellular matrix	Homo sapiens (MMP1_HUMAN)
EGFR Transactivation by Gastrin	Homo sapiens (MMP3_HUMAN)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l	Homo sapiens (MMP1_HUMAN)