| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 28 | Yes |
Popular Name: 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenyl-pentyl]cyclopentyl]heptanoic 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.92 | 6.08 | -52.29 | 3 | 5 | -1 | 101 | 391.528 | 13 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R1-2-E | Prostanoid EP1 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5600 | 0.26 | Binding ≤ 10μM |
| PE2R2-2-E | Prostanoid EP2 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 2500 | 0.28 | Binding ≤ 10μM |
| PF2R-1-E | Prostaglandin F2-alpha Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 82 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PF2R_HUMAN | P43088 | Prostanoid FP Receptor, Human | 570 | 0.31 | Binding ≤ 1μM |
| PE2R1_HUMAN | P34995 | Prostanoid EP1 Receptor, Human | 1100 | 0.30 | Binding ≤ 10μM |
| PE2R2_HUMAN | P43116 | Prostanoid EP2 Receptor, Human | 2500 | 0.28 | Binding ≤ 10μM |
| PF2R_HUMAN | P43088 | Prostanoid FP Receptor, Human | 570 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
