| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 17 | Yes |
Popular Name: Lidocaine Lidocaine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 137-58-6 , 6108-05-0 , 6108-05-0, 73-78-9 , 6108-05-0, 73-78-9 [anhydrous], 137-58-6 [lidocaine] , 73-78-9 , [137-58-6] , [73-78-9]
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
2',6'-Acetoxylidide, 2-(diethylamino)-
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide, 97.5%
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride hydrate
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (mono-hydrochloride, mono-hydrate)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0; D08127; Lidocaine (TN); Lidocaine hydrochloride monohydrate
73-78-9; Lidoca ne hydrochloride; Prestwick_296
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride, monohydrate
After Burn Double Strength Gel
After Burn Double Strength Spray
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
Alphacaine N; Alphacaine SP; Anestacon; Esracaine; Lidocaton; Lidopen
Alphacaine, Xylocaine, lignocaine
CPD000058189; LIDOCAINE; SAM001247018
Diethylaminoaceto-2,6-xylidide
DIMETHYLPHENYLDIETHYLGLYCINAMID
EPINEPHRINE; IONTOCAINE; LIDOCAINE HYDROCHLORIDE; LS-187941
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
Lidocaine hydrochloride monohydrate
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-Dimethylphenyl)-N2,N2-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
N1-(2,6-dimethylphenyl)-2-(diethylamino)acetamide
N1-(2,6-Dimethylphenyl)-N2,N2-diethylglycinamide
Solarcaine aloe extra burn relief cream
USP); Lidocaine Hydrochloride (FDA); Lignocaine (BAN)
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.13 | 7.96 | -37.59 | 2 | 3 | 1 | 34 | 235.351 | 5 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| biological_use | Local anaesthetic | ZereneX Building Blocks |
| BP | 182 / 4 | TCI |
| ALOGPS_SOLUBILITY | 5.93e-01 g/l | DrugBank-approved |
| Mp [°C] | 66 - 69 | Acros Organics |
| MP | 69 | TCI |
| Purity | 98% | APIChem |
| therap | anesthetic (local), antiarrhythmic | MicroSource Spectrum |
| Indications | anesthetic, antiarrhythmic | KeyOrganics Bioactives |
| Therapy | Anti-arrhythmic; local anesthetic | SMDC Iconix |
| biological_use | Antiarrhythmic agent | IBScreen Bioactives |
| Patent Database Links | EP0826685; EP1405646; EP1438962; EP1488789; EP1514539; EP1559418; EP1576953; EP1586347; EP1586349; EP1629852; EP1637132; EP1639994; EP1685843; EP1700616; EP1702597; EP1710256; EP1716868; EP1731142; EP1743635; EP1762226; EP1762236; EP1764111; EP1772767; EP | ChEBI |
| Patent Database Links | EP1582220; US2004002549; US2007184076; US2007207193; US2007232574; US2007244294; WO2007098408 | ChEBI |
| UniProt Database Links | GLIC_GLOVI; S22A1_BOVIN; S22A1_HUMAN; S22A1_MOUSE; S22A1_PIG; S22A1_RABIT; S22A1_RAT | ChEBI |
| H phrase | H302: Harmful if swallowed | Acros Organics |
| Target | Histamine Receptor | Selleck Chemicals |
| Warnings | IRRITANT | Matrix Scientific |
| biological_use | Local anaesthetic | IBScreen Bioactives IBScreen Bioactives |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : Tocris Cookson Ltd.; NCC_SUPPLIER_STRUCTURE_ID : 101620 | NIH Clinical Collection via PubChem |
| P phrase | P264: Wash face, hands and any exposed skin thoroughly after handling; P270: Do not eat, drink or smoke when using this product; P301+ P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell; P330: Rinse mouth | Acros Organics |
| mechanism | Potassium channel (K ATP and K Vol ) blocker | IBScreen Bioactives |
| R phrase | R22: Harmful if swallowed. | Acros Organics |
| S phrase | S24/25: Avoid contact with skin and eyes. | Acros Organics |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: Tocris Bioscience; SUPPLIER_STRUCTURE_ID: 101620 | NIH Clinical Collection via PubChem |
| Hazard | XN: Harmful | Acros Organics |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50425-3-O | Plasmodium Falciparum (cluster #3 Of 22), Other | Other | 10000 | 0.41 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50425 | Z50425 | Plasmodium Falciparum | 10000 | 0.41 | Functional ≤ 10μM |
