Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-2.14	4.15	-105.46	7	10	0	172	507.657	12	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-2.14	4.61	-102.24	7	10	-1	172	506.649	12	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-2.14	3.83	-75.54	6	10	-1	171	506.649	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-2.14	4.72	-92.15	7	10	0	175	507.657	12	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTA-1-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
FNTB-1-E	Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	3	0.34	Binding ≤ 10μM
PGTB1-1-E	Geranylgeranyl Transferase Type I Beta Subunit (cluster #1 Of 2), Eukaryotic	Eukaryotes	1400	0.23	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTB_RAT	Q02293	Protein Farnesyltransferase Beta Subunit, Rat	2.8	0.34	Binding ≤ 1μM
FNTA_RAT	Q04631	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	2.8	0.34	Binding ≤ 1μM
PGTB1_HUMAN	P53609	Geranylgeranyl Transferase Type I Beta Subunit, Human	1400	0.23	Binding ≤ 10μM
FNTB_RAT	Q02293	Protein Farnesyltransferase Beta Subunit, Rat	2.8	0.34	Binding ≤ 10μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	1400	0.23	Binding ≤ 10μM
FNTA_RAT	Q04631	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	2.8	0.34	Binding ≤ 10μM

Description	Species
Apoptotic cleavage of cellular proteins	Homo sapiens (FNTA_HUMAN)
Inactivation, recovery and regulation of the phototransduction cascade	Homo sapiens (FNTA_HUMAN) Rattus norvegicus (FNTB_RAT)