Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.97	6.95	-98.99	5	10	0	150	535.711	12	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-1.97	7.41	-97.16	5	10	-1	150	534.703	12	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-1.97	6.62	-65.49	4	10	-1	148	534.703	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-1.97	7.78	-184.53	6	10	1	154	536.719	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-1.97	7.47	-94.27	5	10	0	152	535.711	12	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTA-1-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	2	0.33	Binding ≤ 10μM
FNTB-1-E	Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	2	0.33	Binding ≤ 10μM
Z80951-1-O	NIH3T3 (Fibroblasts) (cluster #1 Of 4), Other	Other	1800	0.22	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	1.8	0.33	Binding ≤ 1μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	1.8	0.33	Binding ≤ 1μM
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	1.8	0.33	Binding ≤ 10μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	1.8	0.33	Binding ≤ 10μM
Z80951	Z80951	NIH3T3 (Fibroblasts)	1800	0.22	Functional ≤ 10μM

Description	Species
Apoptotic cleavage of cellular proteins	Homo sapiens (FNTA_HUMAN)
Inactivation, recovery and regulation of the phototransduction cascade	Homo sapiens (FNTA_HUMAN)