| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 27th, 2005 | 24 | Yes |
Popular Name: Norastemizole Norastemizole
Find On: PubMed — Wikipedia — Google
CAS Number: 75970-99-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.26 | 11.33 | -50.34 | 3 | 4 | 1 | 46 | 325.411 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNH2-3-E | HERG (cluster #3 Of 5), Eukaryotic | Eukaryotes | 7550 | 0.30 | Binding ≤ 10μM |
| KCNH2-1-E | HERG (cluster #1 Of 2), Eukaryotic | Eukaryotes | 28 | 0.44 | Functional ≤ 10μM |
| Z50425-3-O | Plasmodium Falciparum (cluster #3 Of 22), Other | Other | 2230 | 0.33 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNH2_HUMAN | Q12809 | HERG, Human | 27.542287 | 0.44 | Binding ≤ 1μM |
| KCNH2_HUMAN | Q12809 | HERG, Human | 27.542287 | 0.44 | Binding ≤ 10μM |
| KCNH2_HUMAN | Q12809 | HERG, Human | 28 | 0.44 | Functional ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 2230 | 0.33 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Voltage gated Potassium channels |
No pre-computed analogs available. Try a structural similarity search.