Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.73	9.46	-86.61	3	9	2	88	562.07	8	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	5.73	6.58	-13.15	1	9	0	85	560.054	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.73	9.31	-85.01	3	9	2	88	562.07	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.73	6.99	-42.68	2	9	1	86	561.062	8	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	101	0.24	Functional ≤ 10μM
Z81057-1-O	HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other	Other	101	0.24	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
Z81057	Z81057	HUVEC (Umbilical Vein Endothelial Cells)	10	0.28	Functional ≤ 10μM
VGFR2_HUMAN	P35968	Vascular Endothelial Growth Factor Receptor 2, Human	0.5	0.33	Functional ≤ 10μM

Description	Species
EPHA-mediated growth cone collapse	Homo sapiens (VGFR2_HUMAN)
Integrin cell surface interactions	Homo sapiens (VGFR2_HUMAN)
Neurophilin interactions with VEGF and VEGFR	Homo sapiens (VGFR2_HUMAN)
VEGF binds to VEGFR leading to receptor dimerization	Homo sapiens (VGFR2_HUMAN)
VEGFA-VEGFR2 Pathway	Homo sapiens (VGFR2_HUMAN)
VEGFR2 mediated cell proliferation	Homo sapiens (VGFR2_HUMAN)