Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.92	4.44	-69	7	10	1	155	572.686	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	0.92	4.15	-34.13	6	10	0	154	571.678	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRD-1-E	Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic	Eukaryotes	28	0.25	Binding ≤ 10μM
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	3	0.28	Binding ≤ 10μM
Z50512-1-O	Cavia Porcellus (cluster #1 Of 7), Other	Other	12	0.26	Functional ≤ 10μM
Z50594-1-O	Mus Musculus (cluster #1 Of 9), Other	Other	32	0.25	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRD_RAT	P33533	Delta Opioid Receptor, Rat	28.3	0.25	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	2.74	0.29	Binding ≤ 1μM
OPRD_RAT	P33533	Delta Opioid Receptor, Rat	28.3	0.25	Binding ≤ 10μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	2.74	0.29	Binding ≤ 10μM
Z50512	Z50512	Cavia Porcellus	11.8	0.26	Functional ≤ 10μM
Z50594	Z50594	Mus Musculus	32.2	0.25	Functional ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRD_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRD_RAT)