| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 26th, 2005 | 33 | Yes |
Popular Name: DX-9065a DX-9065a
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.24 | -3.19 | -80.49 | 6 | 7 | 1 | 129 | 445.543 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10-2-E | Coagulation Factor X (cluster #2 Of 2), Eukaryotic | Eukaryotes | 41 | 0.31 | Binding ≤ 10μM |
| TRY1-1-E | Trypsin I (cluster #1 Of 5), Eukaryotic | Eukaryotes | 620 | 0.26 | Binding ≤ 10μM |
| TRY2-1-E | Trypsin II (cluster #1 Of 3), Eukaryotic | Eukaryotes | 620 | 0.26 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 130 | 0.29 | Binding ≤ 1μM |
| TRY1_HUMAN | P07477 | Trypsin I, Human | 190 | 0.29 | Binding ≤ 1μM |
| TRY2_HUMAN | P07478 | Trypsin II, Human | 620 | 0.26 | Binding ≤ 1μM |
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 130 | 0.29 | Binding ≤ 10μM |
| TRY1_HUMAN | P07477 | Trypsin I, Human | 190 | 0.29 | Binding ≤ 10μM |
| TRY2_HUMAN | P07478 | Trypsin II, Human | 2000 | 0.24 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Alpha-defensins | |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | |
| Collagen degradation | |
| Common Pathway | |
| Extrinsic Pathway | |
| Gamma-carboxylation of protein precursors | |
| Intrinsic Pathway | |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu |
