| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 7th, 2005 | 25 | Yes |
Popular Name: Anandamide Anandamide
Find On: PubMed — Wikipedia — Google
CAS Numbers: 924894-98-4 , 94421-68-8
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.65 | 10.06 | -9.33 | 2 | 3 | 0 | 49 | 347.543 | 16 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| UniProt Database Links | ABHD4_BOVIN; ABHD4_HUMAN; ABHD4_MOUSE; CNR1_FELCA; CNR1_HUMAN; CNR1_MACMU; CNR1_MOUSE; CNR1_PANTR; CNR1_RAT; FAAH1_CAEEL; FAAH1_HUMAN; FAAH1_MOUSE; FAAH1_PIG; FAAH1_RAT; FAAH2_HUMAN; FAAH_ARATH; FAH2A_DANRE; FAH2B_DANRE; HRSL5_HUMAN; HRSL5_MOUSE; NAPEP_BO | ChEBI |
| Patent Database Links | EP1645270; EP1775286; US2002091153; US2002187542; US2004048907; US2004122089; US2004265958; US2006281742; US2007244200; US2007248702; US2007254862; US2007254863; WO2007124169; WO2007125048; WO2007125049 | ChEBI |
| Reactome Database Links | REACT_18279 | ChEBI |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CNR1-3-E | Cannabinoid CB1 Receptor (cluster #3 Of 5), Eukaryotic | Eukaryotes | 89 | 0.39 | Binding ≤ 10μM |
| CNR2-2-E | Cannabinoid CB2 Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 78 | 0.40 | Binding ≤ 10μM |
| FAAH1-6-E | Anandamide Amidohydrolase (cluster #6 Of 7), Eukaryotic | Eukaryotes | 3000 | 0.31 | Binding ≤ 10μM |
| TRPV1-3-E | Vanilloid Receptor (cluster #3 Of 3), Eukaryotic | Eukaryotes | 169 | 0.38 | Binding ≤ 10μM |
| TRPV1-3-E | Vanilloid Receptor (cluster #3 Of 4), Eukaryotic | Eukaryotes | 490 | 0.35 | Functional ≤ 10μM |
| Z50594-4-O | Mus Musculus (cluster #4 Of 9), Other | Other | 53 | 0.41 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CNR1_MOUSE | P47746 | Cannabinoid CB1 Receptor, Mouse | 360 | 0.36 | Binding ≤ 1μM |
| CNR1_HUMAN | P21554 | Cannabinoid CB1 Receptor, Human | 11 | 0.45 | Binding ≤ 1μM |
| CNR1_RAT | P20272 | Cannabinoid CB1 Receptor, Rat | 132 | 0.39 | Binding ≤ 1μM |
| CNR2_RAT | Q9QZN9 | Cannabinoid CB2 Receptor, Rat | 25 | 0.43 | Binding ≤ 1μM |
| CNR2_MOUSE | P47936 | Cannabinoid CB2 Receptor, Mouse | 370 | 0.36 | Binding ≤ 1μM |
| CNR2_HUMAN | P34972 | Cannabinoid CB2 Receptor, Human | 168 | 0.38 | Binding ≤ 1μM |
| TRPV1_RAT | O35433 | Vanilloid Receptor, Rat | 169 | 0.38 | Binding ≤ 1μM |
| FAAH1_HUMAN | O00519 | Anandamide Amidohydrolase, Human | 3400 | 0.31 | Binding ≤ 10μM |
| FAAH1_RAT | P97612 | Anandamide Amidohydrolase, Rat | 3000 | 0.31 | Binding ≤ 10μM |
| CNR1_MOUSE | P47746 | Cannabinoid CB1 Receptor, Mouse | 360 | 0.36 | Binding ≤ 10μM |
| CNR1_HUMAN | P21554 | Cannabinoid CB1 Receptor, Human | 11 | 0.45 | Binding ≤ 10μM |
| CNR1_RAT | P20272 | Cannabinoid CB1 Receptor, Rat | 132 | 0.39 | Binding ≤ 10μM |
| CNR2_MOUSE | P47936 | Cannabinoid CB2 Receptor, Mouse | 1926 | 0.32 | Binding ≤ 10μM |
| CNR2_HUMAN | P34972 | Cannabinoid CB2 Receptor, Human | 168 | 0.38 | Binding ≤ 10μM |
| CNR2_RAT | Q9QZN9 | Cannabinoid CB2 Receptor, Rat | 25 | 0.43 | Binding ≤ 10μM |
| TRPV1_RAT | O35433 | Vanilloid Receptor, Rat | 169 | 0.38 | Binding ≤ 10μM |
| Z50594 | Z50594 | Mus Musculus | 52 | 0.41 | Functional ≤ 10μM |
| TRPV1_HUMAN | Q8NER1 | Vanilloid Receptor, Human | 200 | 0.38 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (i) signalling events | |
| TRP channels |
