| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 5th, 2005 | 24 | No |
Popular Name: Fluoxymesterone Fluoxymesterone
(11beta,17beta)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one
11-beta,17-beta-Dihydroxy-9-alpha-fluoro-17-alpha-methyl-4-androster-3-one
11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androsten-3-one
11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one
17-alpha-Methyl-9-alpha-fluoro-11-beta-hydroxytesterone
17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone
4-08-00-02057 (Beilstein Handbook Reference)
76-43-7; D00327; Fluoxymesterone (JP16/USP/INN); Halotestin (TN)
9-alpha-Fluoro-11-beta,17-beta-dihydroxy-17-alpha-methyl-4-androstene-3-one
9-alpha-Fluoro-11-beta-hydroxy-17-methyltestosterone
9-alpha-Fluoro-17-alpha-methyl-11-beta,17-dihydroxy-4-androsten-3-one
9-Fluoro-11-beta,17-beta-dihydroxy-17-methylandrost-4-en-3-one
9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one
9-fluoro-11beta,17beta-dihydroxy-17alpha-methylandrost-4-en-3-one
9.alpha.-Fluoro-11.beta.,17.beta.-dihydroxy-17.alpha.-methyl-4-androstene-3-one
9.alpha.-Fluoro-11.beta.-hydroxy-17-methyltestosterone
9alpha-fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one
9alpha-Fluoro-11beta,17beta-dihydroxy-17alpha-methyl-4-androstene-3-one
9alpha-Fluoro-11beta,17beta-dihydroxy-17alpha-methylandrost-4-en-3-one
9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone
9alpha-Fluoro-11beta-hydroxy-17alpha-methyltestosterone
9alpha-Fluoro-17alpha-methyl-11beta,17-dihydroxy-4-androsten-3-one
Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11.beta.,17.beta.)-
Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11beta,17beta)-
Androst-4-en-3-one, 9-fluoro-11-beta,17-beta-dihydroxy-17-methyl-
Androst-4-en-3-one, 9-fluoro-11.beta.,17.beta.-dihydroxy-17-methyl-
Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl-
Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl- (VAN)
Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl- (VAN) (8CI)
Fluoro-9-alpha dihydroxy-11-beta,17-beta methyl-17-alpha androstene-4 one-3
Fluoro-9-alpha dihydroxy-11-beta,17-beta methyl-17-alpha androstene-4 one-3 [French]
fluoximesterona; fluoxymesterone; fluoxymesteronum
Fluoxymesterone (JP15/USP/INN)
Testosterone, 9-fluoro-11.beta.-hydroxy-17-methyl-
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.76 | 5.39 | -8.66 | 2 | 3 | 0 | 58 | 336.447 | 0 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Mp [°C] | 240 | Acros Organics |
| ALOGPS_SOLUBILITY | 4.52e-02 g/l | DrugBank-Street Drugs |
| Patent Database Links | EP1537858; EP1538164; EP1580188; EP1717247; EP1803810; EP1862167; EP1900742; EP1938798; EP1990342; US2002165218; US2005002945; US2005130980; US2006014755; US2006030555; US2006035945; US2006040958; US2006041131; US2006069103; US2006094706; US2006106023; US | ChEBI |
| H phrase | H361d: Suspected of damaging the unborn child | Acros Organics |
| P phrase | P281: Use personal protective equipment as required | Acros Organics |
| R phrase | R63: Possible risk of harm to the unborn child. | Acros Organics |
| S phrase | S36/37: Wear suitable protective clothing and gloves. | Acros Organics |
| Hazard | XN: Harmful | Acros Organics |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ANDR-2-E | Androgen Receptor (cluster #2 Of 4), Eukaryotic | Eukaryotes | 4 | 0.49 | Binding ≤ 10μM |
| ANDR-2-E | Androgen Receptor (cluster #2 Of 4), Eukaryotic | Eukaryotes | 6 | 0.48 | Binding ≤ 10μM |
| ANDR-2-E | Androgen Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 0 | 0.00 | Functional ≤ 10μM |
| ANDR-2-E | Androgen Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 0 | 0.00 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ANDR_HUMAN | P10275 | Androgen Receptor, Human | 5.7 | 0.48 | Binding ≤ 1μM |
| ANDR_HUMAN | P10275 | Androgen Receptor, Human | 5.7 | 0.48 | Binding ≤ 10μM |
| ANDR_HUMAN | P10275 | Androgen Receptor, Human | 0.3 | 0.56 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Nuclear Receptor transcription pathway |
