| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 2nd, 2005 | 20 | No |
Popular Name: 2-(6-hydrazinopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 2-(6-hydrazinopurin-9-yl)-5-(hyd…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.09 | -14.75 | -16.19 | 6 | 10 | 0 | 151 | 282.26 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| PUBCHEM_PATENT_ID | EP0607367A1; EP0609375A1; EP0719275A1; US5430027; US5432164; US5578582; US5589467; WO1993008206A1; WO1995007921A1; WO1997033590A1; WO1997033591A1; WO1998001459A1; WO1998016539A1 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AA2AR-1-E | Adenosine A2a Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 7340 | 0.36 | Binding ≤ 10μM |
| Z50425-15-O | Plasmodium Falciparum (cluster #15 Of 22), Other | Other | 7920 | 0.36 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AA2AR_RAT | P30543 | Adenosine A2a Receptor, Rat | 7340 | 0.36 | Binding ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 7480 | 0.36 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Adenosine P1 receptors | |
| G alpha (s) signalling events | |
| NGF-independant TRKA activation |
