|
activated TAK1 mediates p38 MAPK activation |
|
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Activation of ATR in response to replication stress |
|
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Activation of NF-kappaB in B cells |
|
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Activation of NIMA Kinases NEK9, NEK6, NEK7 |
|
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Activation of PPARGC1A (PGC-1alpha) by phosphorylation |
|
|
Activation of the AP-1 family of transcription factors |
|
|
Activation of the pre-replicative complex |
|
|
ADP signalling through P2Y purinoceptor 1 |
|
|
AKT phosphorylates targets in the cytosol |
|
|
APC truncation mutants have impaired AXIN binding |
|
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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins |
|
|
Apoptotic cleavage of cellular proteins |
|
|
ARMS-mediated activation |
|
|
AXIN missense mutants destabilize the destruction complex |
|
|
Beta-catenin phosphorylation cascade |
|
|
CD28 co-stimulation |
|
|
CD28 dependent PI3K/Akt signaling |
|
|
CD28 dependent Vav1 pathway |
|
|
CDK-mediated phosphorylation and removal of Cdc6 |
|
|
CDO in myogenesis |
|
|
Condensation of Prophase Chromosomes |
|
|
Constitutive PI3K/AKT Signaling in Cancer |
|
|
CREB phosphorylation through the activation of Ras |
|
|
CRMPs in Sema3A signaling |
|
|
CTLA4 inhibitory signaling |
|
|
Cyclin A/B1 associated events during G2/M transition |
|
|
Cyclin A:Cdk2-associated events at S phase entry |
|
|
Cyclin E associated events during G1/S transition |
|
|
DAP12 signaling |
|
|
Degradation of beta-catenin by the destruction complex |
|
|
disassembly of the destruction complex and recruitment of AXIN to the membrane |
|
|
DNA Damage/Telomere Stress Induced Senescence |
|
|
Downregulation of ERBB2:ERBB3 signaling |
|
|
Downstream TCR signaling |
|
|
DSCAM interactions |
|
|
EGFR downregulation |
|
|
EGFR interacts with phospholipase C-gamma |
|
|
EGFR Transactivation by Gastrin |
|
|
EPHA-mediated growth cone collapse |
|
|
EPHB-mediated forward signaling |
|
|
ERK/MAPK targets |
|
|
Factors involved in megakaryocyte development and platelet production |
|
|
FCERI mediated MAPK activation |
|
|
FCERI mediated NF-kB activation |
|
|
Frs2-mediated activation |
|
|
G alpha (12/13) signalling events |
|
|
G0 and Early G1 |
|
|
G2 Phase |
|
|
GAB1 signalosome |
|
|
Generation of second messenger molecules |
|
|
Golgi Cisternae Pericentriolar Stack Reorganization |
|
|
GPVI-mediated activation cascade |
|
|
GRB2 events in EGFR signaling |
|
|
GRB2 events in ERBB2 signaling |
|
|
GRB7 events in ERBB2 signaling |
|
|
IKK complex recruitment mediated by RIP1 |
|
|
Interleukin-1 signaling |
|
|
Interleukin-2 signaling |
|
|
IRAK1 recruits IKK complex |
|
|
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation |
|
|
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human |
|
|
KSRP destabilizes mRNA |
|
|
Loss of Nlp from mitotic centrosomes |
|
|
Loss of proteins required for interphase microtubule organization from the ce |
|
|
Meiotic recombination |
|
|
misspliced GSK3beta mutants stabilize beta-catenin |
|
|
Mitotic Metaphase/Anaphase Transition |
|
|
Mitotic Prometaphase |
|
|
Mitotic Telophase/Cytokinesis |
|
|
Nef and signal transduction |
|
|
Nef Mediated CD4 Down-regulation |
|
|
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
|
|
NF-kB is activated and signals survival |
|
|
NOD1/2 Signaling Pathway |
|
|
Orc1 removal from chromatin |
|
|
Oxidative Stress Induced Senescence |
|
|
p38MAPK events |
|
|
p53-Dependent G1 DNA Damage Response |
|
|
p75NTR recruits signalling complexes |
|
|
PD-1 signaling |
|
|
PECAM1 interactions |
|
|
Phosphorylation of CD3 and TCR zeta chains |
|
|
Phosphorylation of Emi1 |
|
|
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 |
|
|
Phosphorylation of the APC/C |
|
|
PI3K events in ERBB2 signaling |
|
|
PIP3 activates AKT signaling |
|
|
Platelet sensitization by LDL |
|
|
PLCG1 events in ERBB2 signaling |
|
|
Polo-like kinase mediated events |
|
|
Recruitment of mitotic centrosome proteins and complexes |
|
|
Regulation of APC/C activators between G1/S and early anaphase |
|
|
Regulation of HSF1-mediated heat shock response |
|
|
Regulation of KIT signaling |
|
|
Regulation of PLK1 Activity at G2/M Transition |
|
|
Resolution of Sister Chromatid Cohesion |
|
|
RIP-mediated NFkB activation via ZBP1 |
|
|
S33 mutants of beta-catenin aren't phosphorylated |
|
|
S37 mutants of beta-catenin aren't phosphorylated |
|
|
S45 mutants of beta-catenin aren't phosphorylated |
|
|
SCF(Skp2)-mediated degradation of p27/p21 |
|
|
Sema4D induced cell migration and growth-cone collapse |
|
|
Senescence-Associated Secretory Phenotype (SASP) |
|
|
Separation of Sister Chromatids |
|
|
SHC1 events in EGFR signaling |
|
|
SHC1 events in ERBB2 signaling |
|
|
Signal transduction by L1 |
|
|
Signaling by constitutively active EGFR |
|
|
Signaling by EGFR |
|
|
Signaling by ERBB2 |
|
|
Signaling by ERBB4 |
|
|
Signaling by SCF-KIT |
|
|
Signalling to p38 via RIT and RIN |
|
|
Spry regulation of FGF signaling |
|
|
Stimuli-sensing channels |
|
|
T41 mutants of beta-catenin aren't phosphorylated |
|
|
TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
|
|
TRAF6 mediated NF-kB activation |
|
|
Translocation of ZAP-70 to Immunological synapse |
|
|
truncations of AMER1 destabilize the destruction complex |
|
|
VEGFA-VEGFR2 Pathway |
|
