Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.82	15.07	-49.22	2	6	1	55	515.509	9	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.82	12.84	-12.35	1	6	0	53	514.501	9	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
5HT2A-1-E	Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 3), Eukaryotic	Eukaryotes	58	0.29	Binding ≤ 10μM
5HT2C-1-E	Serotonin 2c (5-HT2c) Receptor (cluster #1 Of 3), Eukaryotic	Eukaryotes	639	0.25	Binding ≤ 10μM
KCNH2-1-E	HERG (cluster #1 Of 5), Eukaryotic	Eukaryotes	1000	0.24	Binding ≤ 10μM
SC6A4-1-E	Serotonin Transporter (cluster #1 Of 4), Eukaryotic	Eukaryotes	397	0.26	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
KCNH2_HUMAN	Q12809	HERG, Human	1000	0.24	Binding ≤ 1μM
5HT2A_HUMAN	P28223	Serotonin 2a (5-HT2a) Receptor, Human	58	0.29	Binding ≤ 1μM
5HT2C_HUMAN	P28335	Serotonin 2c (5-HT2c) Receptor, Human	639	0.25	Binding ≤ 1μM
SC6A4_HUMAN	P31645	Serotonin Transporter, Human	397	0.26	Binding ≤ 1μM
KCNH2_HUMAN	Q12809	HERG, Human	1000	0.24	Binding ≤ 10μM
5HT2A_HUMAN	P28223	Serotonin 2a (5-HT2a) Receptor, Human	58	0.29	Binding ≤ 10μM
5HT2C_HUMAN	P28335	Serotonin 2c (5-HT2c) Receptor, Human	639	0.25	Binding ≤ 10μM
SC6A4_HUMAN	P31645	Serotonin Transporter, Human	397	0.26	Binding ≤ 10μM

Description	Species
G alpha (q) signalling events	Homo sapiens (5HT2A_HUMAN)
Serotonin receptors	Homo sapiens (5HT2A_HUMAN)
Voltage gated Potassium channels	Homo sapiens (KCNH2_HUMAN)