| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 5th, 2006 | 12 | Yes |
Popular Name: DNC014625 DNC014625
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -4.26 | -5.26 | -44.77 | 0 | 5 | 0 | 85 | 184.176 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GBRA1-8-E | GABA Receptor Alpha-1 Subunit (cluster #8 Of 8), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA2-6-E | GABA Receptor Alpha-2 Subunit (cluster #6 Of 8), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA3-5-E | GABA Receptor Alpha-3 Subunit (cluster #5 Of 8), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA4-5-E | GABA Receptor Alpha-4 Subunit (cluster #5 Of 7), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA5-4-E | GABA Receptor Alpha-5 Subunit (cluster #4 Of 8), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA6-4-E | GABA Receptor Alpha-6 Subunit (cluster #4 Of 8), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRB1-4-E | GABA Receptor Beta-1 Subunit (cluster #4 Of 6), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRB2-7-E | GABA Receptor Beta-2 Subunit (cluster #7 Of 7), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRB3-6-E | GABA Receptor Beta-3 Subunit (cluster #6 Of 6), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRG1-4-E | GABA Receptor Gamma-1 Subunit (cluster #4 Of 7), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRG2-7-E | GABA Receptor Gamma-2 Subunit (cluster #7 Of 7), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRG3-5-E | GABA Receptor Gamma-3 Subunit (cluster #5 Of 7), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| GBRP-6-E | GABA Receptor Pi Subunit (cluster #6 Of 6), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| Q91ZM7-3-E | GABA Receptor Theta Subunit (cluster #3 Of 3), Eukaryotic | Eukaryotes | 5000 | 0.62 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GBRA1_RAT | P62813 | GABA Receptor Alpha-1 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA2_RAT | P23576 | GABA Receptor Alpha-2 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA3_RAT | P20236 | GABA Receptor Alpha-3 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA4_RAT | P28471 | GABA Receptor Alpha-4 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA5_RAT | P19969 | GABA Receptor Alpha-5 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRA6_RAT | P30191 | GABA Receptor Alpha-6 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRB1_RAT | P15431 | GABA Receptor Beta-1 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRB2_RAT | P63138 | GABA Receptor Beta-2 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRB3_RAT | P63079 | GABA Receptor Beta-3 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRG1_RAT | P23574 | GABA Receptor Gamma-1 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRG2_RAT | P18508 | GABA Receptor Gamma-2 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRG3_RAT | P28473 | GABA Receptor Gamma-3 Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| GBRP_RAT | O09028 | GABA Receptor Pi Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| Q91ZM7_RAT | Q91ZM7 | GABA Receptor Theta Subunit, Rat | 5000 | 0.62 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| GABA A receptor activation | |
| Ligand-gated ion channel transport |
