Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
3.90 |
11.76 |
-49.24 |
4 |
12 |
1 |
142 |
582.689 |
7 |
↓
|
Hi
High (pH 8-9.5)
|
3.90 |
11.61 |
-49.45 |
4 |
12 |
1 |
142 |
582.689 |
7 |
↓
|
Hi
High (pH 8-9.5)
|
3.90 |
9.41 |
-16.97 |
3 |
12 |
0 |
140 |
581.681 |
7 |
↓
|
Clustered Target Annotations
IGF1R-1-E |
Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
179 |
0.22 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
IRS-related events triggered by IGF1R |
|
SHC-related events triggered by IGF1R |
|
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) |
|
No pre-computed analogs available. Try a structural similarity search.