UCSF

ZINC00000655

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 23rd, 2004 23 Yes

Popular Name: Praziquantel Praziquantel

Find On: PubMed — Wikipedia — Google

CAS Numbers: 1246343-36-1 , 55268-74-1 , [55268-74-1]

Other Names:

(.+-)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1a)isoquinolin-4-one

(11bS)-2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one

(11bS)-2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one; 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-o

antel

135526-78-2

2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one

2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one

2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one

2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one

2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino(2,1a)isoquinolin-4-one

2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazinoe(2,1a)isoquinolin-4-one

2-Cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one

2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one

2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a) isoquinolin-4-one

46648_FLUKA

46648_RIEDEL

4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-

4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-

5-24-03-00361 (Beilstein Handbook Reference)

55268-74-1

55268-74-1; Biltricide (TN); D00471; Praziquantel (JAN/USP/INN)

55268-74-1; C07367; Praziquantel

55268-74-1; CPD000037139; PRAZIQUANTEL; SAM002264632

55268-74-1; Praziquantel; Prestwick_402

57452-31-0

8440, EMBAY

AB00052075

AC-11670

AC1L1J6N

AKOS000541869

Azinox

BAN

BAS 00347357

Bay-8440

Bayer Brand of Praziquantel

Biliricide

Biltricide

Biltricide (TN)

Biltricide, Droncit, Praziquantel

Bio-0456

BPBio1_000088

BRD-A21858158-001-05-2

BRD-A21858158-001-16-9

BRN 0761557

BSPBio_000080

BSPBio_002199

C07367

CCRIS 4114

Cesol

Cestocur

CHEMBL976

CID4891

Cisticid

CPD000037139

CPD000037139; Praziquantel; SAM002264632

Cutter

Cutter Tape Tabs

Cysticide

D00471

D011223

DAP000695

DB01058

DivK1c_000130

Droncit

Drontsit

EINECS 259-559-6

EINECS 260-741-2

Embay 8440

EMBAY-8440

EU-0100909

FDA

HMS1568D22

HMS1920J06

HMS2090J19

HMS2092A09

HMS500G12

I06-0088

IDI1_000130

InChI=1/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H

INN

JAN

KBio1_000130

KBio2_001599

KBio2_004167

KBio2_006735

KBio3_001699

KBioGR_000963

KBioSS_001599

LS-23174

LS-7155

Merck Brand of Praziquantel

MFCD00058531

MLS000028528

MLS000038419

MLS001201812

MLS001304085

MolPort-001-926-470

NCGC00015818-05

NCGC00015818-11

NCGC00089733-02

NCGC00089733-03

NCGC00089733-04

NCGC00089733-05

NINDS_000130

NPFAPI-02

Oprea1_163497

OR-5538

P 4668

P4668_SIGMA

Prasiquantel

Praziquantel (BAN

Praziquantel (Biltricide)

Praziquantel (FDA

Praziquantel (JAN/USP/INN)

Praziquantel D11

Praziquantel [USAN:INN:BAN:JAN]

Praziquantel, (+-)-Isomer

Praziquantel, (R)-Isomer

Praziquantel, (S)-Isomer

Praziquantel, Antibiotic for Culture Media Use Only

Praziquantelum

Praziquantelum [INN-Latin]

Prestwick0_000260

Prestwick1_000260

Prestwick2_000260

Prestwick3_000260

Prestwick_402

Pyquiton

S1691_Selleck

SAM002264632

SMR000037139

SPBio_001295

SPBio_002299

SPECTRUM1500494

Spectrum2_001288

Spectrum3_000550

Spectrum4_000482

Spectrum5_001064

Spectrum_001119

STK030186

Traziquantel

UNII-6490C9U457

USAN

USP)

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.74 8.72 -10.26 0 4 0 41 312.413 1 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 3.81e-01 g/l DrugBank-approved
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
biological_use Anthelmintic IBScreen Bioactives
therap anthelmintic; EMBAY-8440 MicroSource Spectrum
Target Antifection Selleck Chemicals
mechanism Causes in susceptible worms: loss of intracellular calcium IBScreen Bioactives
mechanism disintegration of the schistosome tegument. IBScreen Bioactives
mechanism massive contractions IBScreen Bioactives
mechanism Membrane permeabilizer IBScreen Bioactives IBScreen Bioactives
mechanism musculature paralysis IBScreen Bioactives
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : P-1997 NIH Clinical Collection via PubChem
Target Others Selleck Chemicals
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: P-1997 NIH Clinical Collection via PubChem
mechanism vacuolization IBScreen Bioactives

Activity (Go SEA)

Rings

Analogs ( Draw Identity 99% 90% 80% 70% )