Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.99	9.59	-10.04	2	5	0	51	443.378	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.99	11.82	-48.3	3	5	1	53	444.386	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
5HT1A-4-E	Serotonin 1a (5-HT1a) Receptor (cluster #4 Of 4), Eukaryotic	Eukaryotes	193	0.31	Binding ≤ 10μM
DRD1-2-E	Dopamine D1 Receptor (cluster #2 Of 4), Eukaryotic	Eukaryotes	931	0.28	Binding ≤ 10μM
DRD3-1-E	Dopamine D3 Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
DRD4-4-E	Dopamine D4 Receptor (cluster #4 Of 4), Eukaryotic	Eukaryotes	640	0.29	Binding ≤ 10μM
DRD3-1-E	Dopamine D3 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.38	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1_HUMAN	P21728	Dopamine D1 Receptor, Human	931	0.28	Binding ≤ 1μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	0.44	0.44	Binding ≤ 1μM
DRD4_HUMAN	P21917	Dopamine D4 Receptor, Human	640	0.29	Binding ≤ 1μM
5HT1A_HUMAN	P08908	Serotonin 1a (5-HT1a) Receptor, Human	193	0.31	Binding ≤ 1μM
DRD1_HUMAN	P21728	Dopamine D1 Receptor, Human	931	0.28	Binding ≤ 10μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	0.44	0.44	Binding ≤ 10μM
DRD4_HUMAN	P21917	Dopamine D4 Receptor, Human	640	0.29	Binding ≤ 10μM
5HT1A_HUMAN	P08908	Serotonin 1a (5-HT1a) Receptor, Human	193	0.31	Binding ≤ 10μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	7	0.38	Functional ≤ 10μM