UCSF

ZINC00896681

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
September 30th, 2005 21 Yes

Popular Name: Trimeprazine tartrate Trimeprazine tartrate

Find On: PubMed — Wikipedia — Google

CAS Numbers: 4330-99-8 , 4330-99-8, 41375-66-0 [replaced], 84-96-8 [trimeprazine] , 4330-99-8, 84-96-8 [trime , 84-96-8

Other Names:

(+-)-Alimemazine

(+-)-Trimeprazine

10-(2-Methyl-3-dimethylaminopropyl)-phenothiazine

10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine

10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine tartrate (2:1); 10H-Phenothiazine-10-propanamine N,N,beta-trimethyl-, (R-(R*,R*))-2,3-dihydroxybutanedioate (2:1); Alimemazin (RR)-tartrat; Alimemazine tartrate; Bayer 1219; C18H22N2S.C4H6O6; EINECS 224-3

10-(3-Dimethylamino-2-methylpropyl)phenothiazine

10H-Phenothiazine-10-propanamine, N,N,.beta.-trimethyl-

10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-

4330-99-8; Alimemazine tartrate (JP16); Alimezine (TN); D02245; Trimeprazine tartrate (USP)

4330-99-8; Prestwick_144; Trimeprazine tartrate

84-96-8

84-96-8; Alimemazine (INN); D07125; Repeltin (TN); Trimeprazine (BAN)

84-96-8; Alimemazine; C07172; Methylpromazine; Trimeprazine

AB00053560

AC-19920

AC1L1KNH

Alimemazina

Alimemazina [INN-Spanish]

Alimemazine

Alimemazine (BAN

Alimemazine (INN

Alimemazine (INN)

Alimemazine S,S-dioxide

Alimemazine [INN:BAN]

Alimemazine;Methylpromazine;Trimeperazine

Alimemazinum

Alimemazinum [INN-Latin]

Alimezine

BAN); Alimemazine Tartrate (JAN); Trimeprazine Tartrate (FDA

Bayer 1219

C07172

CHEBI:157833

CHEMBL829

CID5574

D07125

DAP001077

DB01246

dl-Trimeprazine

Dosegran

Doxergan

Dysedon

EINECS 201-577-3

HSDB 3197

Imakol

INN); Trimeprazine Tartrate (FDA

Isobutrazine

L000989

Levoprome

LS-105476

Methylpromazine

MolPort-005-938-362

N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine

N,N,2-trimethyl-3-phenothiazin-10-ylpropan-1-amine

N,N,beta-Trimethyl-10H-phenothiazine-10-propanamine

nchembio.154-comp18

NSC17475

NSC17476

Oxomemazin

Oxomemazina [INN-Spanish]

Oxomemazine

Oxomemazine [DCF:INN]

Oxomemazinum [INN-Latin]

Oxymemazine

Panectyl

Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-

QTL1_000086

Repeltin

Repeltin (TN)

Repetin

Temaril

Teralen

Theralene

Trimeperazine

Trimeprazine

Trimeprazine (BAN)

Trimeprazine 5,5-dioxide

Trimeprazine hemi-(+)tartrate

Trimeprazine Tartrat

UNII-76H78MJJ52

USP)

USP); Alimemazine Tartrate (JAN)

Vallergan

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.85 11.77 -38.72 1 2 1 9 299.463 4 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 8.35e-03 g/l DrugBank-approved
Therapy antipruritic SMDC MicroSource

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDR5-1-F Pleiotropic ABC Efflux Transporter Of Multiple Drugs (cluster #1 Of 1), Fungal Fungi 9600 0.33 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDR5_YEAST P33302 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 9600 0.33 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )