Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
CAH-1-A	Carbonic Anhydrase (cluster #1 Of 2), Archaea	Archaea	190	0.59	Binding ≤ 10μM
CYNT-1-B	Carbonic Anhydrase (cluster #1 Of 3), Bacterial	Bacteria	2010	0.50	Binding ≤ 10μM
Y1284-1-B	Uncharacterized Protein Rv1284/MT1322 (cluster #1 Of 2), Bacterial	Bacteria	872	0.53	Binding ≤ 10μM
B5SU02-2-E	Alpha Carbonic Anhydrase (cluster #2 Of 6), Eukaryotic	Eukaryotes	431	0.56	Binding ≤ 10μM
C0IX24-1-E	Carbonic Anhydrase (cluster #1 Of 5), Eukaryotic	Eukaryotes	79	0.62	Binding ≤ 10μM
CAH1-5-E	Carbonic Anhydrase I (cluster #5 Of 12), Eukaryotic	Eukaryotes	374	0.56	Binding ≤ 10μM
CAH12-1-E	Carbonic Anhydrase XII (cluster #1 Of 9), Eukaryotic	Eukaryotes	56	0.63	Binding ≤ 10μM
CAH13-1-E	Carbonic Anhydrase XIII (cluster #1 Of 7), Eukaryotic	Eukaryotes	23	0.67	Binding ≤ 10μM
CAH14-1-E	Carbonic Anhydrase XIV (cluster #1 Of 8), Eukaryotic	Eukaryotes	345	0.57	Binding ≤ 10μM
CAH15-2-E	Carbonic Anhydrase 15 (cluster #2 Of 6), Eukaryotic	Eukaryotes	95	0.61	Binding ≤ 10μM
CAH2-6-E	Carbonic Anhydrase II (cluster #6 Of 15), Eukaryotic	Eukaryotes	9	0.70	Binding ≤ 10μM
CAH4-1-E	Carbonic Anhydrase IV (cluster #1 Of 16), Eukaryotic	Eukaryotes	380	0.56	Binding ≤ 10μM
CAH5A-1-E	Carbonic Anhydrase VA (cluster #1 Of 10), Eukaryotic	Eukaryotes	81	0.62	Binding ≤ 10μM
CAH5B-1-E	Carbonic Anhydrase VB (cluster #1 Of 9), Eukaryotic	Eukaryotes	91	0.62	Binding ≤ 10μM
CAH6-7-E	Carbonic Anhydrase VI (cluster #7 Of 8), Eukaryotic	Eukaryotes	79	0.62	Binding ≤ 10μM
CAH7-1-E	Carbonic Anhydrase VII (cluster #1 Of 8), Eukaryotic	Eukaryotes	6	0.72	Binding ≤ 10μM
CAH9-1-E	Carbonic Anhydrase IX (cluster #1 Of 11), Eukaryotic	Eukaryotes	501	0.55	Binding ≤ 10μM
CAH1-2-E	Carbonic Anhydrase I (cluster #2 Of 3), Eukaryotic	Eukaryotes	1200	0.52	Functional ≤ 10μM
CAH2-1-E	Carbonic Anhydrase II (cluster #1 Of 2), Eukaryotic	Eukaryotes	38	0.65	Functional ≤ 10μM
CAH4-1-E	Carbonic Anhydrase IV (cluster #1 Of 2), Eukaryotic	Eukaryotes	380	0.56	Functional ≤ 10μM
CAN-1-F	Carbonic Anhydrase (cluster #1 Of 3), Fungal	Fungi	103	0.61	Binding ≤ 10μM
Q5AJ71-1-F	Carbonic Anhydrase (cluster #1 Of 4), Fungal	Fungi	910	0.53	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
B5SU02_9CNID	B5SU02	Alpha Carbonic Anhydrase, 9cnid	431	0.56	Binding ≤ 1μM
CAN_YEAST	P53615	Carbonic Anhydrase, Yeast	103	0.61	Binding ≤ 1μM
C0IX24_9CNID	C0IX24	Carbonic Anhydrase, 9cnid	79	0.62	Binding ≤ 1μM
CAH_METTE	P40881	Carbonic Anhydrase, Mette	150	0.60	Binding ≤ 1μM
Q5AJ71_CANAL	Q5AJ71	Carbonic Anhydrase, Canal	38	0.65	Binding ≤ 1μM
CYNT_HELPY	O24855	Carbonic Anhydrase 1, Helpy	363	0.56	Binding ≤ 1μM
CAH15_MOUSE	Q99N23	Carbonic Anhydrase 15, Mouse	95	0.61	Binding ≤ 1μM
CAH1_HUMAN	P00915	Carbonic Anhydrase I, Human	25	0.67	Binding ≤ 1μM
CAH2_HUMAN	P00918	Carbonic Anhydrase II, Human	38	0.65	Binding ≤ 1μM
CAH4_BOVIN	Q95323	Carbonic Anhydrase IV, Bovin	380	0.56	Binding ≤ 1μM
CAH4_HUMAN	P22748	Carbonic Anhydrase IV, Human	95	0.61	Binding ≤ 1μM
CAH9_HUMAN	Q16790	Carbonic Anhydrase IX, Human	34	0.65	Binding ≤ 1μM
CAH5A_HUMAN	P35218	Carbonic Anhydrase VA, Human	630	0.54	Binding ≤ 1μM
CAH5A_MOUSE	P23589	Carbonic Anhydrase VA, Mouse	640	0.54	Binding ≤ 1μM
CAH5B_HUMAN	Q9Y2D0	Carbonic Anhydrase VB, Human	21	0.67	Binding ≤ 1μM
CAH5B_MOUSE	Q9QZA0	Carbonic Anhydrase VB, Mouse	640	0.54	Binding ≤ 1μM
CAH6_HUMAN	P23280	Carbonic Anhydrase VI, Human	134	0.60	Binding ≤ 1μM
CAH7_HUMAN	P43166	Carbonic Anhydrase VII, Human	26	0.66	Binding ≤ 1μM
CAH12_HUMAN	O43570	Carbonic Anhydrase XII, Human	50	0.64	Binding ≤ 1μM
CAH13_MOUSE	Q9D6N1	Carbonic Anhydrase XIII, Mouse	23	0.67	Binding ≤ 1μM
CAH13_HUMAN	Q8N1Q1	Carbonic Anhydrase XIII, Human	23	0.67	Binding ≤ 1μM
CAH14_HUMAN	Q9ULX7	Carbonic Anhydrase XIV, Human	345	0.57	Binding ≤ 1μM
Y1284_MYCTU	P64797	Uncharacterized Protein Rv1284/MT1322, Myctu	872	0.53	Binding ≤ 1μM
B5SU02_9CNID	B5SU02	Alpha Carbonic Anhydrase, 9cnid	431	0.56	Binding ≤ 10μM
Q5AJ71_CANAL	Q5AJ71	Carbonic Anhydrase, Canal	38	0.65	Binding ≤ 10μM
CYNT_MYCTU	O53573	Carbonic Anhydrase, Myctu	2010	0.50	Binding ≤ 10μM
CAN_YEAST	P53615	Carbonic Anhydrase, Yeast	103	0.61	Binding ≤ 10μM
C0IX24_9CNID	C0IX24	Carbonic Anhydrase, 9cnid	79	0.62	Binding ≤ 10μM
CAH_METTE	P40881	Carbonic Anhydrase, Mette	150	0.60	Binding ≤ 10μM
CYNT_HELPY	O24855	Carbonic Anhydrase 1, Helpy	363	0.56	Binding ≤ 10μM
CAH15_MOUSE	Q99N23	Carbonic Anhydrase 15, Mouse	95	0.61	Binding ≤ 10μM
CAH1_HUMAN	P00915	Carbonic Anhydrase I, Human	1200	0.52	Binding ≤ 10μM
CAH2_HUMAN	P00918	Carbonic Anhydrase II, Human	38	0.65	Binding ≤ 10μM
CAH4_BOVIN	Q95323	Carbonic Anhydrase IV, Bovin	380	0.56	Binding ≤ 10μM
CAH4_HUMAN	P22748	Carbonic Anhydrase IV, Human	95	0.61	Binding ≤ 10μM
CAH9_HUMAN	Q16790	Carbonic Anhydrase IX, Human	34	0.65	Binding ≤ 10μM
CAH5A_HUMAN	P35218	Carbonic Anhydrase VA, Human	630	0.54	Binding ≤ 10μM
CAH5A_MOUSE	P23589	Carbonic Anhydrase VA, Mouse	640	0.54	Binding ≤ 10μM
CAH5B_HUMAN	Q9Y2D0	Carbonic Anhydrase VB, Human	21	0.67	Binding ≤ 10μM
CAH5B_MOUSE	Q9QZA0	Carbonic Anhydrase VB, Mouse	640	0.54	Binding ≤ 10μM
CAH6_HUMAN	P23280	Carbonic Anhydrase VI, Human	134	0.60	Binding ≤ 10μM
CAH7_HUMAN	P43166	Carbonic Anhydrase VII, Human	26	0.66	Binding ≤ 10μM
CAH12_HUMAN	O43570	Carbonic Anhydrase XII, Human	50	0.64	Binding ≤ 10μM
CAH13_HUMAN	Q8N1Q1	Carbonic Anhydrase XIII, Human	23	0.67	Binding ≤ 10μM
CAH13_MOUSE	Q9D6N1	Carbonic Anhydrase XIII, Mouse	1450	0.51	Binding ≤ 10μM
CAH14_HUMAN	Q9ULX7	Carbonic Anhydrase XIV, Human	1540	0.51	Binding ≤ 10μM
Y1284_MYCTU	P64797	Uncharacterized Protein Rv1284/MT1322, Myctu	872	0.53	Binding ≤ 10μM
CAH1_HUMAN	P00915	Carbonic Anhydrase I, Human	1200	0.52	Functional ≤ 10μM
CAH2_HUMAN	P00918	Carbonic Anhydrase II, Human	38	0.65	Functional ≤ 10μM
CAH4_BOVIN	Q95323	Carbonic Anhydrase IV, Bovin	380	0.56	Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description	Species
Erythrocytes take up carbon dioxide and release oxygen	Bos taurus (CAH4_BOVIN) Homo sapiens (CAH1_HUMAN)
Erythrocytes take up oxygen and release carbon dioxide	Homo sapiens (CAH1_HUMAN) Bos taurus (CAH4_BOVIN)
Regulation of gene expression by Hypoxia-inducible Factor	Homo sapiens (CAH9_HUMAN)
Reversible hydration of carbon dioxide	Homo sapiens (CAH12_HUMAN) Bos taurus (CAH4_BOVIN) Mus musculus (CAH5A_MOUSE)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.

Synonyms (99)
Vendors (15)
Annotations (25)
Representations (1)
Notes (2)
Targets (50)
Clustered (22)
Reactome (4)
Rings (0)
Analogs (0)