UCSF

ADAM17, Mouse (1 Compounds)

Swissprot:
ADA17_MOUSE
Stitch:
ADA17_MOUSE
UniProt:
Q9Z0F8
ChEMBL:
CHEMBL4379
Reactome:
REACT_199055
REACT_198614
REACT_198574
REACT_218614
REACT_247063
REACT_242976
REACT_256171
PDB:
Adam17

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 0 0 1
Binding ≤ 1μM 0 0 0 0

Reactome Network (7)

Reactome ID Description Species
REACT_199055 Collagen degradation Mus musculus
REACT_198614 Growth hormone receptor signaling Mus musculus
REACT_198574 Nuclear signaling by ERBB4 Mus musculus
REACT_218614 Regulated proteolysis of p75NTR Mus musculus
REACT_247063 Release of Hh-Np from the secreting cell Mus musculus
REACT_242976 Signaling by EGFR Mus musculus
REACT_256171 TNF signaling Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 1,592 7 5 20
ADA17_PIG O77636 CHEMBL3332 ADAM17, Pig 418 0 0 1
ADA17_RAT Q9Z1K9 CHEMBL2523 ADAM17, Rat 7 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 4 4 4 3
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 4 4 4 3
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4 4 4 3
ADA_MOUSE P03958 CHEMBL3206 Adenosine Deaminase, Mouse 6 1 4 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
ADA17-1-E ADAM17 (cluster #1 Of 2), Eukaryotic 1,066 3 3 8
ADA17-2-E ADAM17 (cluster #2 Of 2), Eukaryotic 911 4 2 14
Uniprot Swissprot Chembl Description Number Shared
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 1
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 1