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AK1C2_HUMAN - Aldo-keto Reductase Family 1 Member C2, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Aldo-keto Reductase Family 1 Member C2, Human (19 Compounds)

Swissprot:
AK1C2_HUMAN
Stitch:
AK1C2_HUMAN
UniProt:
P52895
ChEMBL:
CHEMBL5847
Reactome:
REACT_11053
REACT_11048
REACT_11041
PDB:
1IHI (DOCK)
1J96 (DOCK)
1XJB (DOCK)
2HDJ (DOCK)
2IPJ (DOCK)
AKR1C2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 19 9 3 1
Binding ≤ 1μM 14 6 3 1

Reactome Network (3)

Reactome ID Description Species
REACT_11053 Synthesis of bile acids and bile salts via 24-hydroxycholesterol Homo sapiens
REACT_11048 Synthesis of bile acids and bile salts via 27-hydroxycholesterol Homo sapiens
REACT_11041 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AK1C1_HUMAN Q04828 CHEMBL5905 Aldo-keto Reductase Family 1 Member C1, Human 15
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 5

Synthesis of bile acids and bile salts via 27-hydroxycholesterol

Uniprot Swissprot Chembl Description Number Shared
AK1C1_HUMAN Q04828 CHEMBL5905 Aldo-keto Reductase Family 1 Member C1, Human 15
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 5

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Uniprot Swissprot Chembl Description Number Shared
AK1C1_HUMAN Q04828 CHEMBL5905 Aldo-keto Reductase Family 1 Member C1, Human 15
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 5
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AK1C1_HUMAN Q04828 CHEMBL5905 Aldo-keto Reductase Family 1 Member C1, Human 17 6 2 1
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 37 13 4 4

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AK1C1_HUMAN Q04828 CHEMBL5905 Aldo-keto Reductase Family 1 Member C1, Human 15
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 5
PERM_HUMAN P05164 CHEMBL2439 Myeloperoxidase, Human 1
TTHY_HUMAN P02766 CHEMBL3194 Transthyretin, Human 1