UCSF

Transthyretin, Human (24 Compounds)

Swissprot:
TTHY_HUMAN
Stitch:
TTHY_HUMAN
UniProt:
P02766
ChEMBL:
CHEMBL3194
Reactome:
REACT_75925
REACT_163874
REACT_160130
REACT_24968
REACT_160156
PDB:
1BM7 (DOCK)
1BMZ (DOCK)
1BZ8 (DOCK)
1BZD (DOCK)
1BZE (DOCK)
1DVQ (DOCK)
1DVS (DOCK)
1DVT (DOCK)
1DVU (DOCK)
1DVX (DOCK)
1DVY (DOCK)
1DVZ (DOCK)
1E3F (DOCK)
1E4H (DOCK)
1E5A (DOCK)
1ETA (DOCK)
1ETB (DOCK)
1F41 (DOCK)
1F64 (DOCK)
1F86 (DOCK)
1FH2 (DOCK)
1FHN (DOCK)
1G1O (DOCK)
1GKO (DOCK)
1ICT (DOCK)
1III (DOCK)
1IIK (DOCK)
1IJN (DOCK)
1QAB (DOCK)
1QWH (DOCK)
1RLB (DOCK)
1SOK (DOCK)
1SOQ (DOCK)
1THA (DOCK)
1THC (DOCK)
1TLM (DOCK)
1TSH (DOCK)
1TT6 (DOCK)
1TTA (DOCK)
1TTB (DOCK)
1TTC (DOCK)
1TTR (DOCK)
1TYR (DOCK)
1TZ8 (DOCK)
1U21 (DOCK)
1X7S (DOCK)
1X7T (DOCK)
1Y1D (DOCK)
1Z7J (DOCK)
1ZCR (DOCK)
1ZD6 (DOCK)
2B14 (DOCK)
2B15 (DOCK)
2B16 (DOCK)
2B77 (DOCK)
2B9A (DOCK)
2F7I (DOCK)
2F8I (DOCK)
2FBR (DOCK)
2FLM (DOCK)
2G3X (DOCK)
2G3Z (DOCK)
2G4E (DOCK)
2G4G (DOCK)
2G5U (DOCK)
2G9K (DOCK)
2GAB (DOCK)
2H4E (DOCK)
2NOY (DOCK)
2PAB (DOCK)
2QEL (DOCK)
2QGB (DOCK)
2QGC (DOCK)
2QGD (DOCK)
2QGE (DOCK)
2ROX (DOCK)
2ROY (DOCK)
2TRH (DOCK)
2TRY (DOCK)
2WQA (DOCK)
3A4D (DOCK)
3A4E (DOCK)
3A4F (DOCK)
3B56 (DOCK)
3BSZ (DOCK)
3BT0 (DOCK)
3CBR (DOCK)
3CFM (DOCK)
3CFN (DOCK)
3CFQ (DOCK)
3CFT (DOCK)
3CN0 (DOCK)
3CN1 (DOCK)
3CN2 (DOCK)
3CN3 (DOCK)
3CN4 (DOCK)
3CXF (DOCK)
3D2T (DOCK)
3D7P (DOCK)
3DGD (DOCK)
3DID (DOCK)
3DJR (DOCK)
3DJS (DOCK)
3DJT (DOCK)
3DJZ (DOCK)
3DK0 (DOCK)
3DK2 (DOCK)
3DO4 (DOCK)
3ESN (DOCK)
3ESO (DOCK)
3ESP (DOCK)
3FC8 (DOCK)
3FCB (DOCK)
3GLZ (DOCK)
3GPS (DOCK)
3GRB (DOCK)
3GRG (DOCK)
3GS0 (DOCK)
3GS4 (DOCK)
3GS7 (DOCK)
3HJ0 (DOCK)
3I9A (DOCK)
3I9I (DOCK)
3I9P (DOCK)
3IMR (DOCK)
3IMS (DOCK)
3IMT (DOCK)
3IMU (DOCK)
3IMV (DOCK)
3IMW (DOCK)
3IPB (DOCK)
3IPE (DOCK)
3KGS (DOCK)
3KGT (DOCK)
3KGU (DOCK)
3M1O (DOCK)
3NEE (DOCK)
3NEO (DOCK)
3NES (DOCK)
3NEX (DOCK)
3NG5 (DOCK)
3OZK (DOCK)
3OZL (DOCK)
3P3R (DOCK)
3P3S (DOCK)
3P3T (DOCK)
3P3U (DOCK)
3SSG (DOCK)
3TFB (DOCK)
5TTR (DOCK)
TTR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 24 10 2 3
Binding ≤ 1μM 9 2 0 0
Functional ≤ 10μM 11 2 0 0
Uniprot Swissprot Chembl Description Number Shared
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
TTHY-1-E Transthyretin (cluster #1 Of 3), Eukaryotic 22 8 1 2
TTHY-2-E Transthyretin (cluster #2 Of 3), Eukaryotic 1 1 1 1
TTHY-3-E Transthyretin (cluster #3 Of 3), Eukaryotic 1 1 0 0
Uniprot Swissprot Chembl Description Number Shared
AK1C2_HUMAN P52895 CHEMBL5847 Aldo-keto Reductase Family 1 Member C2, Human 1
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 1
EST1_HUMAN P23141 CHEMBL2265 Acyl Coenzyme A:cholesterol Acyltransferase, Human 1
FABP4_HUMAN P15090 CHEMBL2083 Fatty Acid Binding Protein Adipocyte, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
PERM_HUMAN P05164 CHEMBL2439 Myeloperoxidase, Human 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1