UCSF

Cytochrome P450 1A2, Human (270 Compounds)

Swissprot:
CP1A2_HUMAN
Stitch:
CP1A2_HUMAN
UniProt:
P05177
ChEMBL:
CHEMBL3356
Reactome:
REACT_228214
REACT_13721
REACT_6946
REACT_150134
REACT_150417
PDB:
2HI4 (DOCK)
CYP1A2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
ADME/T ≤ 10μM 270 62 37 15
Uniprot Swissprot Chembl Description Number Shared
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 87

Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)

Uniprot Swissprot Chembl Description Number Shared
CP1A1_HUMAN P04798 CHEMBL2231 Cytochrome P450 1A1, Human 42
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 41
CP2C8_HUMAN P10632 CHEMBL3721 Cytochrome P450 2C8, Human 3
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9, Human 87
CP2CJ_HUMAN P33261 CHEMBL3622 Cytochrome P450 2C19, Human 60
CP4AB_HUMAN Q02928 CHEMBL3978 Cytochrome P450 4A11, Human 23
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 23

Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)

Uniprot Swissprot Chembl Description Number Shared
CP1A1_HUMAN P04798 CHEMBL2231 Cytochrome P450 1A1, Human 42
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 41
CP2C8_HUMAN P10632 CHEMBL3721 Cytochrome P450 2C8, Human 3
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9, Human 87
CP2CJ_HUMAN P33261 CHEMBL3622 Cytochrome P450 2C19, Human 60
HYES_HUMAN P34913 CHEMBL2409 Epoxide Hydratase, Human 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9, Human 87
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 87
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 66
CP2CJ_HUMAN P33261 CHEMBL3622 Cytochrome P450 2C19, Human 60
CP1A1_HUMAN P04798 CHEMBL2231 Cytochrome P450 1A1, Human 42
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 35
CP2B6_HUMAN P20813 CHEMBL4729 Cytochrome P450 2B6, Human 6
CP2C8_HUMAN P10632 CHEMBL3721 Cytochrome P450 2C8, Human 3
CP2A5_MOUSE P20852 CHEMBL4085 Cytochrome P450 2A5, Mouse 2
CP2A6_HUMAN P11509 CHEMBL5282 Cytochrome P450 2A6, Human 2
Z102164 Z102164 CHEMBL613373 Liver Microsomes 2
Z102178 Z102178 CHEMBL613694 Liver Microsomes 2
CP2E1_HUMAN P05181 CHEMBL5281 Cytochrome P450 2E1, Human 1
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 1