Annotation Type | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|
ADME/T ≤ 10μM | 270 | 62 | 37 | 15 |
Reactome ID | Description | Species |
---|---|---|
REACT_228214 | Aflatoxin activation and detoxification | Homo sapiens |
REACT_13721 | Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 | Homo sapiens |
REACT_6946 | Methylation | Homo sapiens |
REACT_150134 | Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) | Homo sapiens |
REACT_150417 | Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) | Homo sapiens |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
CP3A4_HUMAN | P08684 | CHEMBL340 | Cytochrome P450 3A4, Human | 87 |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
CP1A1_HUMAN | P04798 | CHEMBL2231 | Cytochrome P450 1A1, Human | 42 |
CP1B1_HUMAN | Q16678 | CHEMBL4878 | Cytochrome P450 1B1, Human | 41 |
CP2C8_HUMAN | P10632 | CHEMBL3721 | Cytochrome P450 2C8, Human | 3 |
CP2C9_HUMAN | P11712 | CHEMBL3397 | Cytochrome P450 2C9, Human | 87 |
CP2CJ_HUMAN | P33261 | CHEMBL3622 | Cytochrome P450 2C19, Human | 60 |
CP4AB_HUMAN | Q02928 | CHEMBL3978 | Cytochrome P450 4A11, Human | 23 |
CP4F2_HUMAN | P78329 | CHEMBL3379 | Cytochrome P450 4F2, Human | 23 |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
CP1A1_HUMAN | P04798 | CHEMBL2231 | Cytochrome P450 1A1, Human | 42 |
CP1B1_HUMAN | Q16678 | CHEMBL4878 | Cytochrome P450 1B1, Human | 41 |
CP2C8_HUMAN | P10632 | CHEMBL3721 | Cytochrome P450 2C8, Human | 3 |
CP2C9_HUMAN | P11712 | CHEMBL3397 | Cytochrome P450 2C9, Human | 87 |
CP2CJ_HUMAN | P33261 | CHEMBL3622 | Cytochrome P450 2C19, Human | 60 |
HYES_HUMAN | P34913 | CHEMBL2409 | Epoxide Hydratase, Human | 1 |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
CP2C9_HUMAN | P11712 | CHEMBL3397 | Cytochrome P450 2C9, Human | 87 |
CP3A4_HUMAN | P08684 | CHEMBL340 | Cytochrome P450 3A4, Human | 87 |
CP2D6_HUMAN | P10635 | CHEMBL289 | Cytochrome P450 2D6, Human | 66 |
CP2CJ_HUMAN | P33261 | CHEMBL3622 | Cytochrome P450 2C19, Human | 60 |
CP1A1_HUMAN | P04798 | CHEMBL2231 | Cytochrome P450 1A1, Human | 42 |
CP1B1_HUMAN | Q16678 | CHEMBL4878 | Cytochrome P450 1B1, Human | 35 |
CP2B6_HUMAN | P20813 | CHEMBL4729 | Cytochrome P450 2B6, Human | 6 |
CP2C8_HUMAN | P10632 | CHEMBL3721 | Cytochrome P450 2C8, Human | 3 |
CP2A5_MOUSE | P20852 | CHEMBL4085 | Cytochrome P450 2A5, Mouse | 2 |
CP2A6_HUMAN | P11509 | CHEMBL5282 | Cytochrome P450 2A6, Human | 2 |
Z102164 | Z102164 | CHEMBL613373 | Liver Microsomes | 2 |
Z102178 | Z102178 | CHEMBL613694 | Liver Microsomes | 2 |
CP2E1_HUMAN | P05181 | CHEMBL5281 | Cytochrome P450 2E1, Human | 1 |
Z81115 | Z81115 | CHEMBL398 | KB (Squamous Cell Carcinoma) | 1 |