UCSF

Heat Shock Protein HSP 90 (HSP82), Yeast (11 Compounds)

Swissprot:
HSP82_YEAST
Stitch:
HSP82_YEAST
UniProt:
P02829
ChEMBL:
CHEMBL3536
Reactome:
REACT_247584
REACT_209789
REACT_219346
REACT_189032
REACT_189008
REACT_189238
REACT_241435
PDB:
1A4H (DOCK)
1AH6 (DOCK)
1AH8 (DOCK)
1AM1 (DOCK)
1AMW (DOCK)
1BGQ (DOCK)
1HK7 (DOCK)
1US7 (DOCK)
1USU (DOCK)
1USV (DOCK)
1ZW9 (DOCK)
1ZWH (DOCK)
2AKP (DOCK)
2BRC (DOCK)
2BRE (DOCK)
2CG9 (DOCK)
2CGE (DOCK)
2CGF (DOCK)
2FXS (DOCK)
2IWS (DOCK)
2IWU (DOCK)
2IWX (DOCK)
2VW5 (DOCK)
2VWC (DOCK)
2WEP (DOCK)
2WEQ (DOCK)
2WER (DOCK)
2XD6 (DOCK)
2XX2 (DOCK)
2XX4 (DOCK)
2XX5 (DOCK)
2YGA (DOCK)
2YGE (DOCK)
2YGF (DOCK)
3C0E (DOCK)
3C11 (DOCK)
3FP2 (DOCK)
HSP82

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 11 3 2 1
Binding ≤ 1μM 4 1 1 0

Reactome Network (7)

Reactome ID Description Species
REACT_247584 eNOS activation Saccharomyces cerevisiae
REACT_209789 HSF1 activation Saccharomyces cerevisiae
REACT_219346 HSF1-dependent transactivation Saccharomyces cerevisiae
REACT_189032 Signaling by constitutively active EGFR Saccharomyces cerevisiae
REACT_189008 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Saccharomyces cerevisiae
REACT_189238 The NLRP3 inflammasome Saccharomyces cerevisiae
REACT_241435 VEGFR2 mediated vascular permeability Saccharomyces cerevisiae
Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

HSF1 activation

Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

HSF1-dependent transactivation

Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

Signaling by constitutively active EGFR

Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

The NLRP3 inflammasome

Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

VEGFR2 mediated vascular permeability

Uniprot Swissprot Chembl Description Number Shared
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 10
HS90A_HUMAN P07900 CHEMBL3880 Heat Shock Protein HSP 90-alpha, Human 4
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 3
HS90B_HUMAN P08238 CHEMBL4303 Heat Shock Protein HSP 90-beta, Human 2
CBR1_HUMAN P16152 CHEMBL5586 Carbonyl Reductase [NADPH] 1, Human 1
HSP90_RABIT P11500 CHEMBL1667702 Heat Shock Protein HSP 90, Rabit 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
SRC_RAT Q9WUD9 CHEMBL3014 Tyrosine-protein Kinase SRC, Rat 1