UCSF

Tyrosine-protein Kinase JAK3, Mouse (2 Compounds)

Swissprot:
JAK3_MOUSE
Stitch:
JAK3_MOUSE
UniProt:
Q62137
ChEMBL:
CHEMBL5250
Reactome:
REACT_210793
REACT_261365
REACT_198701
PDB:
Jak3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2 1 1 1
Binding ≤ 1μM 1 1 1 1
Functional ≤ 10μM 1 1 0 1

Reactome Network (3)

Reactome ID Description Species
REACT_210793 Interleukin receptor SHC signaling Mus musculus
REACT_261365 Interleukin-2 signaling Mus musculus
REACT_198701 Interleukin-7 signaling Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 474 27 8 19
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
JAK1_MOUSE P52332 CHEMBL2968 Tyrosine-protein Kinase JAK1, Mouse 1 1 0 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
JAK3-1-E Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic 334 18 6 12
JAK3-2-E Tyrosine-protein Kinase JAK3 (cluster #2 Of 2), Eukaryotic 143 9 2 7
Uniprot Swissprot Chembl Description Number Shared
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 2
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
JAK1_MOUSE P52332 CHEMBL2968 Tyrosine-protein Kinase JAK1, Mouse 1
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 1
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 1
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 1
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 1
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 1
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 1
Z80109 Z80109 CHEMBL614565 CTLL (Cytotoxic T-cells) 1