| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 22 | 1 | 0 | 0 |
| Binding ≤ 1μM | 22 | 1 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_235261 | CD28 dependent PI3K/Akt signaling | Rattus norvegicus |
| REACT_198729 | Constitutive PI3K/AKT Signaling in Cancer | Rattus norvegicus |
| REACT_216105 | HSF1-dependent transactivation | Rattus norvegicus |
| REACT_239343 | mTOR signalling | Rattus norvegicus |
| REACT_257653 | PIP3 activates AKT signaling | Rattus norvegicus |
| REACT_231506 | Release of eIF4E | Rattus norvegicus |
| REACT_242748 | S6K1-mediated signalling | Rattus norvegicus |
| REACT_256841 | VEGFR2 mediated vascular permeability | Rattus norvegicus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| MTOR_HUMAN | P42345 | CHEMBL2842 | FK506 Binding Protein 12, Human | 912 | 27 | 2 | 6 |
| MTOR_MOUSE | Q9JLN9 | CHEMBL1255165 | Serine/threonine-protein Kinase MTOR, Mouse | 58 | 2 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| MTOR-1-E | Serine/threonine-protein Kinase MTOR (cluster #1 Of 3), Eukaryotic | 22 | 5 | 1 | 1 |
| MTOR-2-E | Serine/threonine-protein Kinase MTOR (cluster #2 Of 3), Eukaryotic | 899 | 22 | 1 | 5 |
| MTOR-3-E | Serine/threonine-protein Kinase MTOR (cluster #3 Of 3), Eukaryotic | 51 | 2 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PK3CA_HUMAN | P42336 | CHEMBL4005 | PI3-kinase P110-alpha Subunit, Human | 19 |
| PK3CB_HUMAN | P42338 | CHEMBL3145 | PI3-kinase P110-beta Subunit, Human | 1 |
| PK3CD_HUMAN | O00329 | CHEMBL3130 | PI3-kinase P110-delta Subunit, Human | 1 |
| PK3CG_HUMAN | P48736 | CHEMBL3267 | PI3-kinase P110-gamma Subunit, Human | 1 |