| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 247 | 1 | 0 | 0 |
| Binding ≤ 1μM | 192 | 1 | 0 | 0 |
| Functional ≤ 10μM | 142 | 2 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_118572 | Degradation of the extracellular matrix | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| NICA_HUMAN | Q92542 | CHEMBL3418 | Nicastrin, Human | 384 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| PSN2_HUMAN | P49810 | CHEMBL3708 | Presenilin 2, Human | 246 | 0 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| APH1A_HUMAN | Q96BI3 | CHEMBL2362 | Gamma-secretase Subunit APH-1A, Human | 384 |
| NICA_HUMAN | Q92542 | CHEMBL3418 | Nicastrin, Human | 384 |
| PEN2_HUMAN | Q9NZ42 | CHEMBL2374 | Gamma-secretase Subunit PEN-2, Human | 384 |
| PSN2_HUMAN | P49810 | CHEMBL3708 | Presenilin 2, Human | 384 |
| APH1B_HUMAN | Q8WW43 | CHEMBL2385 | Gamma-secretase Subunit APH-1B, Human | 315 |
| BACE1_HUMAN | P56817 | CHEMBL4822 | Beta-secretase 1, Human | 3 |
| Z80936 | Z80936 | CHEMBL614818 | HEK293 (Embryonic Kidney Fibroblasts) | 3 |
