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PSN1_HUMAN - Presenilin 1, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Presenilin 1, Human (247 Compounds)

Swissprot:
PSN1_HUMAN
Stitch:
PSN1_HUMAN
UniProt:
P49768
ChEMBL:
CHEMBL2473
Reactome:
REACT_118572
PDB:
2KR6 (DOCK)
PSEN1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 247 1 0 0
Binding ≤ 1μM 192 1 0 0
Functional ≤ 10μM 142 2 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_118572 Degradation of the extracellular matrix Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
NICA_HUMAN Q92542 CHEMBL3418 Nicastrin, Human 384
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PSN2_HUMAN P49810 CHEMBL3708 Presenilin 2, Human 246 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
APH1A_HUMAN Q96BI3 CHEMBL2362 Gamma-secretase Subunit APH-1A, Human 384
NICA_HUMAN Q92542 CHEMBL3418 Nicastrin, Human 384
PEN2_HUMAN Q9NZ42 CHEMBL2374 Gamma-secretase Subunit PEN-2, Human 384
PSN2_HUMAN P49810 CHEMBL3708 Presenilin 2, Human 384
APH1B_HUMAN Q8WW43 CHEMBL2385 Gamma-secretase Subunit APH-1B, Human 315
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 3
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 3

Most Common Rings