UCSF

Glyoxalase I, Human (42 Compounds)

Swissprot:
LGUL_HUMAN
Stitch:
LGUL_HUMAN
UniProt:
Q04760
ChEMBL:
CHEMBL2424
PDB:
1BH5 (DOCK)
1FRO (DOCK)
1QIN (DOCK)
1QIP (DOCK)
GLO1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 42 14 6 3
Binding ≤ 1μM 18 5 1 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LGUL_YEAST P50107 CHEMBL6057 Lactoylglutathione Lyase, Yeast 7 1 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
LGUL-1-E Glyoxalase I (cluster #1 Of 2), Eukaryotic 34 10 1 0
LGUL-1-F Glyoxalase I (cluster #1 Of 1), Fungal 7 1 0 0
LGUL-2-E Glyoxalase I (cluster #2 Of 2), Eukaryotic 11 5 5 3
Uniprot Swissprot Chembl Description Number Shared
GLO2_HUMAN Q16775 CHEMBL2261 Glyoxalase II, Human 8
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 3
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 3
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 3
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 2
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 2
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 2
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 2
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 2
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 2
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 2
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 2
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 2
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 2
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 2
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 2
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 2
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 2
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 2
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 2
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 2
LGUL_YEAST P50107 CHEMBL6057 Lactoylglutathione Lyase, Yeast 2
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 2
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 2
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 2
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 2
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 2
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 2
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 1
A4_HUMAN P05067 CHEMBL2487 Beta Amyloid A4 Protein, Human 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AK1A1_RAT P51635 CHEMBL3871 Aldehyde Reductase, Rat 1
AK1CL_MOUSE Q91WR5 CHEMBL1075270 Aldo-keto Reductase Family 1 Member C21, Mouse 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 1
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 1
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 1
CAH13_MOUSE Q9D6N1 CHEMBL2186 Carbonic Anhydrase XIII, Mouse 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 1
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CD38_HUMAN P28907 CHEMBL4660 Lymphocyte Differentiation Antigen CD38, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 1
DHB3_RAT O54939 CHEMBL1075158 Testosterone 17-beta-dehydrogenase 3, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
FABI_ECOLI P0AEK4 CHEMBL1857 Enoyl-[acyl-carrier-protein] Reductase, Ecoli 1
FPS_FUJSV P00530 CHEMBL5708 Tyrosine-protein Kinase Transforming Protein FPS, Fujsv 1
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 1
KD4DL_HUMAN B2RXH2 CHEMBL1293226 Lysine-specific Demethylase 4D-like, Human 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 1
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 1
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 1
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 1
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
MDH_THETH P10584 CHEMBL4255 Malate Dehydrogenase, Theth 1
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1
MTSI_SPISQ P15840 CHEMBL4373 CpG DNA Methylase, Spisq 1
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 1
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 1
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 1
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 1
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 1
Q8HY88_BOVIN Q8HY88 CHEMBL1075183 Potassium Channel Subfamily K Member 2, Bovin 1
R1AB_CVHSA P0C6X7 CHEMBL5118 Replicase Polyprotein 1ab, Cvhsa 1
TOP1_RAT Q9WUL0 CHEMBL1075164 DNA Topoisomerase 1, Rat 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1

Most Common Rings