UCSF

Beta Amyloid A4 Protein, Human (224 Compounds)

Swissprot:
A4_HUMAN
Stitch:
A4_HUMAN
UniProt:
P05067
ChEMBL:
CHEMBL2487
Reactome:
REACT_25195
REACT_75925
REACT_163773
REACT_163906
REACT_21264
REACT_19231
REACT_18283
REACT_318
REACT_118563
REACT_21281
REACT_75808
REACT_24969
PDB:
1AAP (DOCK)
1AMB (DOCK)
1AMC (DOCK)
1AML (DOCK)
1BA4 (DOCK)
1BA6 (DOCK)
1BJB (DOCK)
1BJC (DOCK)
1BRC (DOCK)
1CA0 (DOCK)
1HZ3 (DOCK)
1IYT (DOCK)
1MWP (DOCK)
1OWT (DOCK)
1QCM (DOCK)
1QWP (DOCK)
1QXC (DOCK)
1QYT (DOCK)
1TAW (DOCK)
1TKN (DOCK)
1UO7 (DOCK)
1UO8 (DOCK)
1UOA (DOCK)
1UOI (DOCK)
1X11 (DOCK)
1Z0Q (DOCK)
1ZE7 (DOCK)
1ZE9 (DOCK)
1ZJD (DOCK)
2BEG (DOCK)
2BOM (DOCK)
2BP4 (DOCK)
2FJZ (DOCK)
2FK1 (DOCK)
2FK2 (DOCK)
2FK3 (DOCK)
2FKL (DOCK)
2FMA (DOCK)
2G47 (DOCK)
2IPU (DOCK)
2LFM (DOCK)
2LMN (DOCK)
2LMO (DOCK)
2LMP (DOCK)
2LMQ (DOCK)
2OTK (DOCK)
2R0W (DOCK)
2WK3 (DOCK)
2Y29 (DOCK)
2Y2A (DOCK)
2Y3J (DOCK)
2Y3K (DOCK)
2Y3L (DOCK)
3AYU (DOCK)
3DXC (DOCK)
3DXD (DOCK)
3DXE (DOCK)
3GCI (DOCK)
3IFL (DOCK)
3IFN (DOCK)
3IFO (DOCK)
3IFP (DOCK)
3JTI (DOCK)
3KTM (DOCK)
3L33 (DOCK)
3L81 (DOCK)
3MOQ (DOCK)
3MXC (DOCK)
3MXY (DOCK)
3NYJ (DOCK)
3NYL (DOCK)
3OVJ (DOCK)
3OW9 (DOCK)
3U0T (DOCK)
3UMH (DOCK)
3UMI (DOCK)
3UMK (DOCK)
APP

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 224 33 3 1
Binding ≤ 1μM 190 30 3 1
Functional ≤ 10μM 21 0 0 0

Reactome Network (12)

Reactome ID Description Species
REACT_25195 Advanced glycosylation endproduct receptor signaling Homo sapiens
REACT_75925 Amyloids Homo sapiens
REACT_163773 DEx/H-box helicases activate type I IFN and inflammatory cytokines production Homo sapiens
REACT_163906 ECM proteoglycans Homo sapiens
REACT_21264 Formyl peptide receptors bind formyl peptides and many other ligands Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_318 Platelet degranulation Homo sapiens
REACT_118563 RIP-mediated NFkB activation via ZBP1 Homo sapiens
REACT_21281 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Homo sapiens
REACT_75808 The NLRP3 inflammasome Homo sapiens
REACT_24969 TRAF6 mediated NF-kB activation Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
A1Z199_HUMAN A1Z199 CHEMBL6105 BCR/ABL P210 Fusion Protein, Human 24 2 1 1
A8K327_HUMAN A8K327 CHEMBL3046 Sialidase 3, Human 51 11 3 14
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 2,632 98 19 17
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 2,605 153 29 23
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 1,141 51 14 12
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2,729 151 60 41
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 14 14 5 9
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 16 2 0 1
AAKG1_HUMAN P54619 CHEMBL2393 AMP-activated Protein Kinase, Gamma-1 Subunit, Human 14 2 0 1
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 12 11 4 5
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 21 9 2 4
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 39 8 3 4
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 84 8 5 5
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 83 30 35 9
ABD12_HUMAN Q8N2K0 CHEMBL5516 Monoacylglycerol Lipase ABHD12, Human 1 1 1 1
ABHGA_HUMAN O95870 CHEMBL6168 Protein BAT5, Human 1 1 1 1
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 930 96 23 42
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 110 20 10 14
ABP1_HUMAN P19801 CHEMBL2118 Diamine Oxidase, Human 20 5 0 1
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 279 0 0 0
ACACB_HUMAN O00763 CHEMBL4829 Acetyl-CoA Carboxylase 2, Human 452 1 0 0
ACCN2_HUMAN P78348 CHEMBL1628477 Amiloride-sensitive Cation Channel 2, Neuronal, Human 1 0 0 0
ACCN3_HUMAN Q9UHC3 CHEMBL5368 Amiloride-sensitive Cation Channel 3, Human 37 2 1 1
ACE2_HUMAN Q9BYF1 CHEMBL3736 Angiotensin-converting Enzyme 2, Human 205 16 5 5
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1,893 166 81 42
ACE_HUMAN P12821 CHEMBL1808 Angiotensin-converting Enzyme, Human 1,168 112 39 37
ACH10_HUMAN Q9GZZ6 CHEMBL2551 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human 5 3 1 0
ACHA2_HUMAN Q15822 CHEMBL1794 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human 24 6 4 4
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 84 15 7 7
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 140 21 4 4
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 5 3 1 0
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 5 3 1 0
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 142 31 15 10
ACHA9_HUMAN Q9UGM1 CHEMBL2184 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human 1 1 0 0
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 8 3 1 0
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 64 13 8 7
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 24 5 3 2
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 43 8 6 5
ACHB_HUMAN P11230 CHEMBL3355 Acetylcholine Receptor Protein Beta Chain, Human 4 2 1 0
ACHD_HUMAN Q07001 CHEMBL3011 Acetylcholine Receptor Protein Delta Chain, Human 17 4 3 1
ACHE_HUMAN Q04844 CHEMBL2484 Acetylcholine Receptor Protein Epsilon Chain, Human 6 3 2 1
ACHG_HUMAN P07510 CHEMBL2613 Acetylcholine Receptor Protein Gamma Chain, Human 4 2 1 0
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 67 8 5 7
ACLY_HUMAN P53396 CHEMBL3720 ATP-citrate Synthase, Human 37 1 0 0
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1,053 70 41 43
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1,202 58 34 37
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1,056 55 33 35
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 536 44 30 27
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 470 45 23 24
ACOD_HUMAN O00767 CHEMBL5555 Acyl-CoA Desaturase, Human 286 4 0 0
ACV1B_HUMAN P36896 CHEMBL5310 Activin Receptor Type-1B, Human 6 6 2 3
ACVL1_HUMAN P37023 CHEMBL5311 Serine/threonine-protein Kinase Receptor R3, Human 3 3 2 2
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 8 8 6 6
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 168 1 1 2
ADA12_HUMAN O43184 CHEMBL5030 ADAM12, Human 8 8 1 1
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 1,592 7 5 20
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1,217 94 55 50
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1,203 86 55 50
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1,085 77 49 46
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 690 104 52 54
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 422 76 40 40
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 620 92 51 50
ADA33_HUMAN Q9BZ11 CHEMBL6121 Disintegrin And Metalloproteinase Domain-containing Protein 33, Human 3 0 0 1
ADAM8_HUMAN P78325 CHEMBL5665 Disintegrin And Metalloproteinase Domain-containing Protein 8, Human 1 0 0 0
ADAM9_HUMAN Q13443 CHEMBL5982 ADAM9, Human 66 1 1 1
ADA_HUMAN P00813 CHEMBL1910 Adenosine Deaminase, Human 57 6 3 12
ADCK3_HUMAN Q8NI60 CHEMBL5550 Chaperone Activity Of Bc1 Complex-like, Mitochondrial, Human 6 5 3 4
ADCK4_HUMAN Q96D53 CHEMBL5753 Uncharacterized AarF Domain-containing Protein Kinase 4, Human 8 7 3 5
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 75 8 8 7
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 30 7 7 6
ADCY3_HUMAN O60266 CHEMBL3164 Adenylate Cyclase Type III, Human 24 1 1 0
ADCY4_HUMAN Q8NFM4 CHEMBL2533 Adenylate Cyclase Type IV, Human 23 0 0 0
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 46 3 1 0
ADCY6_HUMAN O43306 CHEMBL3221 Adenylate Cyclase Type VI, Human 24 1 1 0
ADCY7_HUMAN P51828 CHEMBL4922 Adenylate Cyclase Type VII, Human 24 1 1 0
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 30 7 7 6
ADCY9_HUMAN O60503 CHEMBL2655 Adenylate Cyclase Type IX, Human 24 1 1 0
ADCYA_HUMAN Q96PN6 CHEMBL5854 Adenylate Cyclase Type 10, Human 5 4 1 1
ADH1A_HUMAN P07327 CHEMBL1970 Alcohol Dehydrogenase Alpha Chain, Human 26 6 2 5
ADH1B_HUMAN P00325 CHEMBL3284 Alcohol Dehydrogenase Beta Chain, Human 14 5 2 5
ADH1G_HUMAN P00326 CHEMBL3285 Alcohol Dehydrogenase Gamma Chain, Human 11 2 2 4
ADH4_HUMAN P08319 CHEMBL2990 Alcohol Dehydrogenase Class II, Human 3 0 0 0
ADH6_HUMAN P28332 CHEMBL4765 Alcohol Dehydrogenase 6, Human 4 0 0 0
ADH7_HUMAN P40394 CHEMBL3867 Alcohol Dehydrogenase Class IV, Human 5 0 0 1
ADHX_HUMAN P11766 CHEMBL4116 Alcohol Dehydrogenase Class III, Human 4 0 0 0
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 416 8 1 7
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 760 58 28 26
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 834 83 38 41
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 495 33 9 11
AGAL_HUMAN P06280 CHEMBL2524 Alpha-galactosidase A, Human 2 2 1 1
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 1,045 14 9 13
AGTR2_HUMAN P50052 CHEMBL4607 Angiotensin II Type 2 (AT-2) Receptor, Human 493 12 7 4
AHR_HUMAN P35869 CHEMBL3201 Aryl Hydrocarbon Receptor, Human 1 1 1 1
AK1A1_HUMAN P14550 CHEMBL2246 Aldehyde Reductase, Human 23 6 7 7
AK1BA_HUMAN O60218 CHEMBL5983 Aldo-keto Reductase Family 1 Member B10, Human 9 8 5 5
AK1C1_HUMAN Q04828 CHEMBL5905 Aldo-keto Reductase Family 1 Member C1, Human 17 6 2 1
AK1C2_HUMAN P52895 CHEMBL5847 Aldo-keto Reductase Family 1 Member C2, Human 19 9 3 1
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 37 13 4 4
AKAP1_HUMAN Q92667 CHEMBL3678 Protein Kinase A Anchoring Protein 1, Human 13 1 1 1
AKAP2_HUMAN Q9Y2D5 CHEMBL3899 Protein Kinase A Anchoring Protein 2, Human 13 1 1 1
AKIP_HUMAN Q9NWT8 CHEMBL5910 Aurora Kinase A-interacting Protein, Human 2 1 0 0
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1,046 20 3 13
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 390 13 2 14
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 152 9 1 7
AKTS1_HUMAN Q96B36 CHEMBL1255161 Proline-rich AKT1 Substrate 1, Human 3 0 0 0
AL5AP_HUMAN P20292 CHEMBL4550 5-lipoxygenase Activating Protein, Human 181 1 1 1
ALBU_HUMAN P02768 CHEMBL3253 Serum Albumin, Human 11 0 0 0
ALDH2_HUMAN P05091 CHEMBL1935 Aldehyde Dehydrogenase, Human 54 17 8 4
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 630 58 22 25
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 188 39 12 16
AMD_HUMAN P19021 CHEMBL2544 Peptidyl-glycine Alpha-amidating Monooxygenase, Human 2 1 0 0
AMPB_HUMAN Q9H4A4 CHEMBL2432 Aminopeptidase B, Human 23 3 1 2
AMPD1_HUMAN P23109 CHEMBL2869 AMP Deaminase 1, Human 65 0 1 0
AMPD2_HUMAN Q01433 CHEMBL2997 AMP Deaminase 2, Human 127 0 1 0
AMPD3_HUMAN Q01432 CHEMBL2912 AMP Deaminase 3, Human 158 0 2 2
AMPE_HUMAN Q07075 CHEMBL3439 Aminopeptidase A, Human 94 2 2 2
AMPL_HUMAN P28838 CHEMBL3965 Leucine Aminopeptidase, Human 71 14 4 5
AMPM1_HUMAN P53582 CHEMBL2474 Methionine Aminopeptidase 1, Human 36 12 2 2
AMPM2_HUMAN P50579 CHEMBL3922 Methionine Aminopeptidase 2, Human 343 13 2 10
AMPN_HUMAN P15144 CHEMBL1907 Aminopeptidase N, Human 297 4 3 9
AMY1_HUMAN P04745 CHEMBL2478 Salivary Alpha-amylase, Human 1 1 1 0
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1,635 98 33 25
ANF_HUMAN P01160 CHEMBL1293193 Atrial Natriuretic Factor, Human 11 0 0 1
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 10 9 3 4
ANM1_HUMAN Q99873 CHEMBL5524 Protein-arginine N-methyltransferase 1, Human 9 4 1 1
ANM3_HUMAN O60678 CHEMBL5891 Protein Arginine N-methyltransferase 3, Human 0 0 0 0
ANPRA_HUMAN P16066 CHEMBL1988 Atrial Natriuretic Peptide Receptor A, Human 2 1 0 0
ANPRC_HUMAN P17342 CHEMBL2247 Atrial Natriuretic Peptide Receptor C, Human 1 0 0 0
ANT3_HUMAN P01008 CHEMBL1950 Antithrombin-III Precursor, Human 1 1 0 0
ANXA2_HUMAN P07355 CHEMBL1764938 Annexin A2, Human 53 9 0 0
AOC2_HUMAN O75106 CHEMBL4112 Retina-specific Amine Oxidase, Copper Containing, Human 8 0 0 0
AOC3_HUMAN Q16853 CHEMBL3437 Amine Oxidase, Copper Containing, Human 100 26 1 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 437 102 46 17
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 606 196 53 32
APEX1_HUMAN P27695 CHEMBL5619 DNA-(apurinic Or Apyrimidinic Site) Lyase, Human 38 18 4 0
APH1A_HUMAN Q96BI3 CHEMBL2362 Gamma-secretase Subunit APH-1A, Human 278 0 0 0
APH1B_HUMAN Q8WW43 CHEMBL2385 Gamma-secretase Subunit APH-1B, Human 277 3 0 0
APOB_HUMAN P04114 CHEMBL4549 Apolipoprotein B-100, Human 79 0 0 0
APOH_HUMAN P02749 CHEMBL2859 Apolipoprotein H, Human 3 0 0 0
ARBK1_HUMAN P25098 CHEMBL4079 G-protein Coupled Receptor Kinase 2, Human 1 1 1 0
ARBK2_HUMAN P35626 CHEMBL1075166 Beta-adrenergic Receptor Kinase 2, Human 1 1 1 0
ARF1_HUMAN P84077 CHEMBL5985 ADP-ribosylation Factor 1, Human 1 1 0 0
ARGI1_HUMAN P05089 CHEMBL1075097 Arginase-1, Human 1 0 0 0
ARGI2_HUMAN P78540 CHEMBL1795148 Arginase-2, Mitochondrial, Human 0 0 0 0
ARY1_HUMAN P18440 CHEMBL5101 Arylamine N-acetyltransferase 1, Human 10 8 0 0
ASND1_HUMAN Q9NWL6 CHEMBL3765 HCV NS3-transactivated Protein 1, Human 15 0 0 0
ASNS_HUMAN P08243 CHEMBL3120 Asparagine Synthetase, Human 1 0 0 0
AT12A_HUMAN P54707 CHEMBL2933 Potassium-transporting ATPase Alpha Chain 2, Human 49 1 1 2
AT1A1_HUMAN P05023 CHEMBL1807 Sodium/potassium-transporting ATPase Alpha-1 Chain, Human 396 5 5 5
AT1A2_HUMAN P50993 CHEMBL2715 Sodium/potassium-transporting ATPase Alpha-2 Chain, Human 396 5 5 5
AT1A3_HUMAN P13637 CHEMBL4052 Sodium/potassium-transporting ATPase Alpha-3 Chain, Human 396 5 5 5
AT1A4_HUMAN Q13733 CHEMBL4053 Sodium/potassium-transporting ATPase Alpha-4 Chain, Human 396 5 5 5
AT1B1_HUMAN P05026 CHEMBL2379 Sodium/potassium-transporting ATPase Beta-1 Chain, Human 392 5 5 4
AT1B2_HUMAN P14415 CHEMBL2332 Sodium/potassium-transporting ATPase Beta-2 Chain, Human 392 5 5 4
AT1B3_HUMAN P54709 CHEMBL3256 Sodium/potassium-transporting ATPase Beta-3 Chain, Human 392 5 5 4
AT2A1_HUMAN O14983 CHEMBL3136 Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 1, Human 16 1 1 0
AT2A2_HUMAN P16615 CHEMBL3901 Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 2, Human 13 1 1 0
ATF1_HUMAN P18846 CHEMBL3255 Activating Transcription Factor 1, Human 18 1 0 0
ATM_HUMAN Q13315 CHEMBL3797 Serine-protein Kinase ATM, Human 22 2 1 0
ATNG_HUMAN P54710 CHEMBL4639 Sodium/potassium-transporting ATPase Gamma Chain, Human 156 5 5 4
ATP4A_HUMAN P20648 CHEMBL1802 Potassium-transporting ATPase Alpha Chain 1, Human 197 11 6 6
ATP4B_HUMAN P51164 CHEMBL5207 Potassium-transporting ATPase Beta Chain, Human 197 11 6 6
ATR_HUMAN Q13535 CHEMBL5024 Serine-protein Kinase ATR, Human 61 7 5 4
ATS1_HUMAN Q9UHI8 CHEMBL5133 ADAMTS1, Human 3 0 0 0
ATS4_HUMAN O75173 CHEMBL2318 ADAMTS4, Human 190 3 0 2
ATS5_HUMAN Q9UNA0 CHEMBL2285 ADAMTS5, Human 352 25 0 2
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 1,035 57 8 26
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 571 38 9 23
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 55 27 9 18
AVR2A_HUMAN P27037 CHEMBL5616 Activin Receptor Type-2A, Human 2 2 1 1
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 7 7 4 4

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
A4-1-E Beta Amyloid A4 Protein (cluster #1 Of 5), Eukaryotic 74 9 2 1
A4-2-E Beta Amyloid A4 Protein (cluster #2 Of 5), Eukaryotic 59 21 1 0
A4-3-E Beta Amyloid A4 Protein (cluster #3 Of 5), Eukaryotic 1 0 0 0
A4-4-E Beta Amyloid A4 Protein (cluster #4 Of 5), Eukaryotic 6 0 0 0
A4-5-E Beta Amyloid A4 Protein (cluster #5 Of 5), Eukaryotic 85 3 0 0
Uniprot Swissprot Chembl Description Number Shared
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 16
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 15
BACE2_HUMAN Q9Y5Z0 CHEMBL2525 Beta Secretase 2, Human 8
HCD2_HUMAN Q99714 CHEMBL4159 Endoplasmic Reticulum-associated Amyloid Beta-peptide-binding Protein, Human 2
LUCI_PHOPE Q27757 CHEMBL5150 Luciferin 4-monooxygenase, Phope 2
LUCI_PHOPY P08659 CHEMBL5567 Luciferin 4-monooxygenase, Phopy 2
APH1A_MOUSE Q8BVF7 CHEMBL3787 Gamma-secretase Subunit APH-1A, Mouse 1
APH1B_MOUSE Q8C7N7 CHEMBL3786 Gamma-secretase Subunit APH-1B, Mouse 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 1
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 1
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
DHB3_RAT O54939 CHEMBL1075158 Testosterone 17-beta-dehydrogenase 3, Rat 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1
MTSI_SPISQ P15840 CHEMBL4373 CpG DNA Methylase, Spisq 1
NICA_MOUSE P57716 CHEMBL4548 Nicastrin, Mouse 1
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 1
PEN2_MOUSE Q9CQR7 CHEMBL4539 Gamma-secretase Subunit PEN-2, Mouse 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PSN1_MOUSE P49769 CHEMBL5128 Presenilin-1, Mouse 1
PSN2_MOUSE Q61144 CHEMBL3483 Presenilin-2, Mouse 1
Q8HY88_BOVIN Q8HY88 CHEMBL1075183 Potassium Channel Subfamily K Member 2, Bovin 1
RENI_HUMAN P00797 CHEMBL286 Renin, Human 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 1
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 1

Most Common Rings