| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 316 | 6 | 4 | 9 |
| Binding ≤ 1μM | 235 | 5 | 4 | 6 |
| Functional ≤ 10μM | 0 | 0 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_208597 | Cell surface interactions at the vascular wall | Bos taurus |
| REACT_220023 | Common Pathway | Bos taurus |
| REACT_209521 | G alpha (q) signalling events | Bos taurus |
| REACT_212120 | Gamma-carboxylation of protein precursors | Bos taurus |
| REACT_206454 | Intrinsic Pathway | Bos taurus |
| REACT_219025 | Peptide ligand-binding receptors | Bos taurus |
| REACT_217199 | Platelet Aggregation (Plug Formation) | Bos taurus |
| REACT_206584 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l | Bos taurus |
| REACT_216886 | Removal of aminoterminal propeptides from gamma-carboxylated proteins | Bos taurus |
| REACT_215912 | Thrombin signalling through proteinase activated receptors (PARs) | Bos taurus |
| REACT_216819 | Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu | Bos taurus |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FA10_BOVIN | P00743 | CHEMBL3656 | Coagulation Factor X, Bovin | 51 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FA10_BOVIN | P00743 | CHEMBL3656 | Coagulation Factor X, Bovin | 51 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FA10_BOVIN | P00743 | CHEMBL3656 | Coagulation Factor X, Bovin | 51 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FA10_BOVIN | P00743 | CHEMBL3656 | Coagulation Factor X, Bovin | 51 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FA10_BOVIN | P00743 | CHEMBL3656 | Coagulation Factor X, Bovin | 51 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| THRB_HUMAN | P00734 | CHEMBL204 | Thrombin, Human | 4,156 | 65 | 14 | 68 |
| THRB_MOUSE | P19221 | CHEMBL1075308 | Prothrombin, Mouse | 2 | 0 | 0 | 0 |
| THRB_RAT | P18292 | CHEMBL3078 | Thrombin, Rat | 64 | 3 | 2 | 7 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| THRB-1-E | Prothrombin (cluster #1 Of 8), Eukaryotic | 3,647 | 18 | 8 | 54 |
| THRB-2-E | Prothrombin (cluster #2 Of 8), Eukaryotic | 47 | 0 | 0 | 0 |
| THRB-3-E | Prothrombin (cluster #3 Of 8), Eukaryotic | 7 | 1 | 0 | 0 |
| THRB-4-E | Prothrombin (cluster #4 Of 8), Eukaryotic | 527 | 6 | 2 | 13 |
| THRB-5-E | Prothrombin (cluster #5 Of 8), Eukaryotic | 40 | 7 | 3 | 7 |
| THRB-6-E | Prothrombin (cluster #6 Of 8), Eukaryotic | 9 | 1 | 0 | 0 |
| THRB-7-E | Prothrombin (cluster #7 Of 8), Eukaryotic | 4 | 0 | 0 | 0 |
| THRB-8-E | Prothrombin (cluster #8 Of 8), Eukaryotic | 285 | 35 | 3 | 4 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| TRY1_BOVIN | P00760 | CHEMBL3769 | Trypsin I, Bovin | 80 |
| TRY2_BOVIN | Q29463 | CHEMBL4472 | Trypsin II, Bovin | 66 |
| PLMN_HUMAN | P00747 | CHEMBL1801 | Plasminogen, Human | 59 |
| FA10_BOVIN | P00743 | CHEMBL3656 | Coagulation Factor X, Bovin | 51 |
| THRB_HUMAN | P00734 | CHEMBL204 | Thrombin, Human | 25 |
| UROK_HUMAN | P00749 | CHEMBL3286 | Urokinase-type Plasminogen Activator, Human | 17 |
| TPA_HUMAN | P00750 | CHEMBL1873 | Tissue-type Plasminogen Activator, Human | 14 |
| TRY1_HUMAN | P07477 | CHEMBL209 | Trypsin I, Human | 11 |
| CATB_BOVIN | P07688 | CHEMBL2323 | Cathepsin B, Bovin | 8 |
| PLMN_BOVIN | P06868 | CHEMBL2957 | Plasminogen, Bovin | 8 |
| FA10_HUMAN | P00742 | CHEMBL244 | Coagulation Factor X, Human | 7 |
| KLKB1_HUMAN | P03952 | CHEMBL2000 | Plasma Kallikrein, Human | 3 |
| THRB_RAT | P18292 | CHEMBL3078 | Thrombin, Rat | 3 |
| TRY2_HUMAN | P07478 | CHEMBL3159 | Trypsin II, Human | 3 |
| TRY3_HUMAN | P35030 | CHEMBL4551 | Trypsin III, Human | 2 |
| ANT3_HUMAN | P01008 | CHEMBL1950 | Antithrombin-III Precursor, Human | 1 |
| TRYB1_HUMAN | Q15661 | CHEMBL2617 | Tryptase Beta-1, Human | 1 |
