| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 30th, 2008 | 43 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.05 | 12.14 | -44.12 | 4 | 9 | 1 | 107 | 594.593 | 7 | ↓ |
| Mid Mid (pH 6-8) | 5.05 | 12 | -41.68 | 4 | 9 | 1 | 107 | 594.593 | 7 | ↓ |
| Mid Mid (pH 6-8) | 5.05 | 9.66 | -11.87 | 3 | 9 | 0 | 105 | 593.585 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10-1-E | Coagulation Factor X (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 0.86 | 0.30 | Binding ≤ 1μM |
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 0.86 | 0.30 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Common Pathway | |
| Extrinsic Pathway | |
| Gamma-carboxylation of protein precursors | |
| Intrinsic Pathway | |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu |
![2-indoxazen-5-yl-N-[4-[2-(piperazinomethyl)phenyl]phenyl]pyrazole-3-carboxamide](http://zinc12.docking.org/img/rings/138568.gif)
