Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.96	10.21	-43.73	1	1	1	4	254.378	0	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.96	7.8	-6.77	0	1	0	3	253.37	0	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1-1-E	Dopamine D1 Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	840	0.47	Binding ≤ 10μM
DRD3-1-E	Dopamine D3 Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	840	0.47	Binding ≤ 10μM
DRD4-3-E	Dopamine D4 Receptor (cluster #3 Of 4), Eukaryotic	Eukaryotes	840	0.47	Binding ≤ 10μM
DRD5-1-E	Dopamine D5 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	840	0.47	Binding ≤ 10μM
DRD2-17-E	Dopamine D2 Receptor (cluster #17 Of 24), Eukaryotic	Eukaryotes	840	0.47	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1_BOVIN	Q95136	Dopamine D1 Receptor, Bovin	840	0.47	Binding ≤ 1μM
DRD2_BOVIN	P20288	Dopamine D2 Receptor, Bovin	840	0.47	Binding ≤ 1μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	840	0.47	Binding ≤ 1μM
DRD4_HUMAN	P21917	Dopamine D4 Receptor, Human	840	0.47	Binding ≤ 1μM
DRD5_HUMAN	P21918	Dopamine D5 Receptor, Human	840	0.47	Binding ≤ 1μM
DRD1_BOVIN	Q95136	Dopamine D1 Receptor, Bovin	7000	0.40	Binding ≤ 10μM
DRD2_BOVIN	P20288	Dopamine D2 Receptor, Bovin	7000	0.40	Binding ≤ 10μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	7000	0.40	Binding ≤ 10μM
DRD4_HUMAN	P21917	Dopamine D4 Receptor, Human	7000	0.40	Binding ≤ 10μM
DRD5_HUMAN	P21918	Dopamine D5 Receptor, Human	7000	0.40	Binding ≤ 10μM

Description	Species
Dopamine receptors	Homo sapiens (DRD4_HUMAN) Bos taurus (DRD1_BOVIN)
G alpha (i) signalling events	Homo sapiens (DRD4_HUMAN)
G alpha (s) signalling events	Homo sapiens (DRD5_HUMAN) Bos taurus (DRD1_BOVIN)