Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.97	11.24	-44.89	4	7	1	77	534.109	6	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	4.97	8.88	-11.89	3	7	0	76	533.101	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.97	11.12	-48.37	4	7	1	77	534.109	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
KIT-1-E	Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	921	0.23	Binding ≤ 10μM
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	199	0.25	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
KIT_HUMAN	P10721	Stem Cell Growth Factor Receptor, Human	921	0.23	Binding ≤ 1μM
VGFR2_HUMAN	P35968	Vascular Endothelial Growth Factor Receptor 2, Human	199	0.25	Binding ≤ 1μM
KIT_HUMAN	P10721	Stem Cell Growth Factor Receptor, Human	921	0.23	Binding ≤ 10μM
VGFR2_HUMAN	P35968	Vascular Endothelial Growth Factor Receptor 2, Human	199	0.25	Binding ≤ 10μM

Description	Species
Constitutive PI3K/AKT Signaling in Cancer	Homo sapiens (KIT_HUMAN)
EPHA-mediated growth cone collapse	Homo sapiens (VGFR2_HUMAN)
Integrin cell surface interactions	Homo sapiens (VGFR2_HUMAN)
Neurophilin interactions with VEGF and VEGFR	Homo sapiens (VGFR2_HUMAN)
PIP3 activates AKT signaling	Homo sapiens (KIT_HUMAN)
Regulation of KIT signaling	Homo sapiens (KIT_HUMAN)
Signaling by SCF-KIT	Homo sapiens (KIT_HUMAN)
VEGF binds to VEGFR leading to receptor dimerization	Homo sapiens (VGFR2_HUMAN)
VEGFA-VEGFR2 Pathway	Homo sapiens (VGFR2_HUMAN)
VEGFR2 mediated cell proliferation	Homo sapiens (VGFR2_HUMAN)