Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1-1-E	Dopamine D1 Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	83	0.58	Binding ≤ 10μM
DRD3-1-E	Dopamine D3 Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	83	0.58	Binding ≤ 10μM
DRD4-3-E	Dopamine D4 Receptor (cluster #3 Of 4), Eukaryotic	Eukaryotes	83	0.58	Binding ≤ 10μM
DRD5-1-E	Dopamine D5 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	83	0.58	Binding ≤ 10μM
Q9WTR4-1-E	Norepinephrine Transporter (cluster #1 Of 2), Eukaryotic	Eukaryotes	270	0.54	Binding ≤ 10μM
SC6A2-1-E	Norepinephrine Transporter (cluster #1 Of 2), Eukaryotic	Eukaryotes	660	0.51	Binding ≤ 10μM
SC6A3-1-E	Dopamine Transporter (cluster #1 Of 3), Eukaryotic	Eukaryotes	79	0.58	Binding ≤ 10μM
SC6A3-1-E	Dopamine Transporter (cluster #1 Of 3), Eukaryotic	Eukaryotes	88	0.58	Binding ≤ 10μM
SC6A4-3-E	Serotonin Transporter (cluster #3 Of 4), Eukaryotic	Eukaryotes	5100	0.44	Binding ≤ 10μM
SC6A2-1-E	Norepinephrine Transporter (cluster #1 Of 3), Eukaryotic	Eukaryotes	51	0.60	Functional ≤ 10μM
SC6A3-1-E	Dopamine Transporter (cluster #1 Of 1), Eukaryotic	Eukaryotes	20	0.63	Functional ≤ 10μM
Z50597-1-O	Rattus Norvegicus (cluster #1 Of 12), Other	Other	171	0.56	Functional ≤ 10μM
Z50597-1-O	Rattus Norvegicus (cluster #1 Of 12), Other	Other	438	0.52	Functional ≤ 10μM
DRD2-2-E	Dopamine D2 Receptor (cluster #2 Of 24), Eukaryotic	Eukaryotes	83	0.58	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1_RAT	P18901	Dopamine D1 Receptor, Rat	164	0.56	Binding ≤ 1μM
DRD2_RAT	P61169	Dopamine D2 Receptor, Rat	164	0.56	Binding ≤ 1μM
DRD3_RAT	P19020	Dopamine D3 Receptor, Rat	164	0.56	Binding ≤ 1μM
DRD4_RAT	P30729	Dopamine D4 Receptor, Rat	164	0.56	Binding ≤ 1μM
DRD5_RAT	P25115	Dopamine D5 Receptor, Rat	164	0.56	Binding ≤ 1μM
SC6A3_HUMAN	Q01959	Dopamine Transporter, Human	121.7	0.57	Binding ≤ 1μM
SC6A3_RAT	P23977	Dopamine Transporter, Rat	83	0.58	Binding ≤ 1μM
Q9WTR4_RAT	Q9WTR4	Norepinephrine Transporter, Rat	989	0.49	Binding ≤ 1μM
SC6A2_HUMAN	P23975	Norepinephrine Transporter, Human	788	0.50	Binding ≤ 1μM
DRD1_RAT	P18901	Dopamine D1 Receptor, Rat	164	0.56	Binding ≤ 10μM
DRD2_RAT	P61169	Dopamine D2 Receptor, Rat	164	0.56	Binding ≤ 10μM
DRD3_RAT	P19020	Dopamine D3 Receptor, Rat	164	0.56	Binding ≤ 10μM
DRD4_RAT	P30729	Dopamine D4 Receptor, Rat	164	0.56	Binding ≤ 10μM
DRD5_RAT	P25115	Dopamine D5 Receptor, Rat	164	0.56	Binding ≤ 10μM
SC6A3_HUMAN	Q01959	Dopamine Transporter, Human	121.7	0.57	Binding ≤ 10μM
SC6A3_RAT	P23977	Dopamine Transporter, Rat	83	0.58	Binding ≤ 10μM
SC6A2_HUMAN	P23975	Norepinephrine Transporter, Human	788	0.50	Binding ≤ 10μM
Q9WTR4_RAT	Q9WTR4	Norepinephrine Transporter, Rat	989	0.49	Binding ≤ 10μM
SC6A4_HUMAN	P31645	Serotonin Transporter, Human	5100	0.44	Binding ≤ 10μM
SC6A3_HUMAN	Q01959	Dopamine Transporter, Human	19.9	0.63	Functional ≤ 10μM
SC6A2_HUMAN	P23975	Norepinephrine Transporter, Human	51	0.60	Functional ≤ 10μM
Z50597	Z50597	Rattus Norvegicus	171	0.56	Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description	Species
Dopamine clearance from the synaptic cleft	Homo sapiens (SC6A3_HUMAN) Rattus norvegicus (SC6A3_RAT)
Dopamine receptors	Rattus norvegicus (DRD3_RAT)
G alpha (i) signalling events	Rattus norvegicus (DRD3_RAT)
Na+/Cl- dependent neurotransmitter transporters	Homo sapiens (SC6A2_HUMAN) Rattus norvegicus (SC6A3_RAT)

Analogs ( Draw Identity 99% 90% 80% 70% )

1267

Synonyms (123)
Vendors (9)
Annotations (25)
Representations (1)
Notes (3)
Targets (22)
Clustered (14)
Reactome (4)
Rings (0)
Analogs (1)