ZINC 12

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Swissprot:: FPPS_HUMAN
Stitch:: FPPS_HUMAN
UniProt:: P14324
ChEMBL:: CHEMBL1782
Reactome:: REACT_147904; REACT_9405
PDB:: 1YQ7 (DOCK); 1YV5 (DOCK); 1ZW5 (DOCK); 2F7M (DOCK); 2F89 (DOCK); 2F8C (DOCK); 2F8Z (DOCK); 2F92 (DOCK); 2F94 (DOCK); 2F9K (DOCK); 2OPM (DOCK); 2OPN (DOCK); 2QIS (DOCK); 2RAH (DOCK); 2VF6 (DOCK); 3B7L (DOCK); 3CP6 (DOCK); 3N1V (DOCK); 3N1W (DOCK); 3N3L (DOCK); 3N45 (DOCK); 3N46 (DOCK); 3N49 (DOCK); 3N5H (DOCK); 3N5J (DOCK); 3N6K (DOCK); 3RYE (DOCK); 3S4J (DOCK); FDPS

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	122	14	8	13
Binding ≤ 1μM	101	12	8	13

Reactome ID	Description	Species
REACT_147904	Activation of gene expression by SREBF (SREBP)	Homo sapiens
REACT_9405	Cholesterol biosynthesis	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	2
GGPPS_HUMAN	O95749	CHEMBL4769	Geranylgeranyl Pyrophosphate Synthetase, Human	16

Uniprot	Swissprot	Chembl	Description	Number Shared
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	2
GGPPS_HUMAN	O95749	CHEMBL4769	Geranylgeranyl Pyrophosphate Synthetase, Human	16

Uniprot	Swissprot	Chembl	Description	Number Shared
Q0GKD7_LEIDO	Q0GKD7	CHEMBL3693	Farnesyl Pyrophosphate Synthase, Leido	32
GGPPS_HUMAN	O95749	CHEMBL4769	Geranylgeranyl Pyrophosphate Synthetase, Human	16
ISPA_ECOLI	P22939	CHEMBL1075078	Geranyltranstransferase, Ecoli	3
Q8ST54_TRYCR	Q8ST54	CHEMBL4151	Hexokinase, Trycr	3
DXR_ECOLI	P45568	CHEMBL4091	1-deoxyxylulose-5-phosphate Reductoisomerase, Ecoli	2
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	2
GGPPS_YEAST	Q12051	CHEMBL1075251	Geranylgeranyl Pyrophosphate Synthase, Yeast	2
Q8MTZ4_9TRYP	Q8MTZ4	CHEMBL4386	Vacuolar-type Proton Translocating Pyrophosphatase 1, 9tryp	2
Q8WS26_TRYCR	Q8WS26	CHEMBL4752	Farnesyl Diphosphate Synthase, Trycr	2
FDFT_RAT	Q02769	CHEMBL3815	Squalene Synthetase, Rat	1
Q197X6_TOXGO	Q197X6	CHEMBL5831	Farnesyl Diphosphate Synthase, Toxgo	1
UPPS_STRPN	Q97SR4	CHEMBL1075025	Undecaprenyl Pyrophosphate Synthase, Strpn	1